These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 25006746)

  • 1. Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes.
    de Bruin G; Huber EM; Xin BT; van Rooden EJ; Al-Ayed K; Kim KB; Kisselev AF; Driessen C; van der Stelt M; van der Marel GA; Groll M; Overkleeft HS
    J Med Chem; 2014 Jul; 57(14):6197-209. PubMed ID: 25006746
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits.
    Maurits E; Degeling CG; Kisselev AF; Florea BI; Overkleeft HS
    Chembiochem; 2020 Nov; 21(22):3220-3224. PubMed ID: 32598532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes.
    Xin BT; de Bruin G; Huber EM; Besse A; Florea BI; Filippov DV; van der Marel GA; Kisselev AF; van der Stelt M; Driessen C; Groll M; Overkleeft HS
    J Med Chem; 2016 Aug; 59(15):7177-87. PubMed ID: 27438186
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits.
    Xin BT; Huber EM; de Bruin G; Heinemeyer W; Maurits E; Espinal C; Du Y; Janssens M; Weyburne ES; Kisselev AF; Florea BI; Driessen C; van der Marel GA; Groll M; Overkleeft HS
    J Med Chem; 2019 Feb; 62(3):1626-1642. PubMed ID: 30657666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of triaryl compounds as novel 20S proteasome inhibitors.
    Yang Y; Wang K; Wu B; Yang Y; Lai F; Chen X; Xiao Z
    Bioorg Med Chem Lett; 2020 Nov; 30(21):127508. PubMed ID: 32853683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome Subunit Selective Activity-Based Probes Report on Proteasome Core Particle Composition in a Native Polyacrylamide Gel Electrophoresis Fluorescence-Resonance Energy Transfer Assay.
    de Bruin G; Xin BT; Florea BI; Overkleeft HS
    J Am Chem Soc; 2016 Aug; 138(31):9874-80. PubMed ID: 27428761
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.
    de Bruin G; Xin BT; Kraus M; van der Stelt M; van der Marel GA; Kisselev AF; Driessen C; Florea BI; Overkleeft HS
    Angew Chem Int Ed Engl; 2016 Mar; 55(13):4199-203. PubMed ID: 26511210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors.
    Downey-Kopyscinski S; Daily EW; Gautier M; Bhatt A; Florea BI; Mitsiades CS; Richardson PG; Driessen C; Overkleeft HS; Kisselev AF
    Blood Adv; 2018 Oct; 2(19):2443-2451. PubMed ID: 30266819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
    Huber EM; de Bruin G; Heinemeyer W; Paniagua Soriano G; Overkleeft HS; Groll M
    J Am Chem Soc; 2015 Jun; 137(24):7835-42. PubMed ID: 26020686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Argyrin B, a non-competitive inhibitor of the human immunoproteasome exhibiting preference for β1i.
    Allardyce DJ; Bell CM; Loizidou EZ
    Chem Biol Drug Des; 2019 Aug; 94(2):1556-1567. PubMed ID: 31074944
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors.
    Maccari R; Ettari R; Adornato I; Naß A; Wolber G; Bitto A; Mannino F; Aliquò F; Bruno G; Nicolò F; Previti S; Grasso S; Zappalà M; Ottanà R
    Bioorg Med Chem Lett; 2018 Feb; 28(3):278-283. PubMed ID: 29292224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two-Step Bioorthogonal Activity-Based Protein Profiling of Individual Human Proteasome Catalytic Sites.
    Xin BT; Espinal C; de Bruin G; Filippov DV; van der Marel GA; Florea BI; Overkleeft HS
    Chembiochem; 2020 Jan; 21(1-2):248-255. PubMed ID: 31597011
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors.
    Singh PK; Fan H; Jiang X; Shi L; Nathan CF; Lin G
    ChemMedChem; 2016 Oct; 11(19):2127-2131. PubMed ID: 27561172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of isoquinolinone derivatives as immunoproteasome inhibitors.
    Ettari R; Iraci N; Di Chio C; Previti S; Danzè M; Zappalà M
    Bioorg Med Chem Lett; 2022 Jan; 55():128478. PubMed ID: 34838650
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Minimal β-Lactone Fragment for Selective β5c or β5i Proteasome Inhibitors.
    Groll M; Korotkov VS; Huber EM; de Meijere A; Ludwig A
    Angew Chem Int Ed Engl; 2015 Jun; 54(27):7810-4. PubMed ID: 25973989
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes.
    Ettari R; Cerchia C; Maiorana S; Guccione M; Novellino E; Bitto A; Grasso S; Lavecchia A; Zappalà M
    ChemMedChem; 2019 Apr; 14(8):842-852. PubMed ID: 30829448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of peptide epoxyketones as selective immunoproteasome inhibitors.
    Li X; Hong D; Zhang M; Xu L; Zhou Y; Li J; Liu T
    Eur J Med Chem; 2021 Oct; 221():113556. PubMed ID: 34087498
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome.
    Culletta G; Tutone M; Ettari R; Perricone U; Di Chio C; Almerico AM; Zappalà M
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37445688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes.
    Villoutreix BO; Khatib AM; Cheng Y; Miteva MA; Maréchal X; Vidal J; Reboud-Ravaux M
    Oncotarget; 2017 Feb; 8(6):10437-10449. PubMed ID: 28060729
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optimization of α-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 (β5i)/LMP2 (β1i) dual inhibitor.
    Arai Y; Shitama H; Yamagishi M; Ono S; Kashima A; Hiraizumi M; Tsuda N; Katayama K; Tanaka K; Koda Y; Kato S; Sakata K; Nureki O; Miyazaki H
    Bioorg Med Chem; 2024 Jul; 109():117790. PubMed ID: 38906067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.