BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 25008456)

  • 1. Design and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents.
    Zhao XB; Goto M; Song ZL; Morris-Natschke SL; Zhao Y; Wu D; Yang L; Li SG; Liu YQ; Zhu GX; Wu XB; Lee KH
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3850-3. PubMed ID: 25008456
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of novel 7-[(
    Song ZL; Yang GZ; Li JC; Liu YQ; Yang CJ; Goto M; Zhang ZJ; Morris-Natschke SL; Liu H; Lee KH
    Nat Prod Res; 2020 Jul; 34(14):2022-2029. PubMed ID: 30784310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agents.
    Zhao XB; Wu D; Wang MJ; Goto M; Morris-Natschke SL; Liu YQ; Wu XB; Song ZL; Zhu GX; Lee KH
    Bioorg Med Chem; 2014 Nov; 22(22):6453-8. PubMed ID: 25438769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction.
    Song ZL; Chen HL; Wang YH; Goto M; Gao WJ; Cheng PL; Morris-Natschke SL; Liu YQ; Zhu GX; Wang MJ; Lee KH
    Bioorg Med Chem Lett; 2015 Jul; 25(13):2690-3. PubMed ID: 25987370
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and cytotoxic activity of novel 7-substituted camptothecin derivatives incorporating piperazinyl-sulfonylamidine moieties.
    Yang CJ; Song ZL; Goto M; Liu YQ; Hsieh KY; Morris-Natschke SL; Zhao YL; Zhang JX; Lee KH
    Bioorg Med Chem Lett; 2017 Sep; 27(17):3959-3962. PubMed ID: 28789891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents.
    Liu YQ; Dai W; Wang CY; Morris-Natschke SL; Zhou XW; Yang L; Yang XM; Li WQ; Lee KH
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7659-61. PubMed ID: 23102893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, cytotoxic activity and molecular docking studies of new 20(S)-sulfonylamidine camptothecin derivatives.
    Song ZL; Wang MJ; Li L; Wu D; Wang YH; Yan LT; Morris-Natschke SL; Liu YQ; Zhao YL; Wang CY; Liu H; Goto M; Liu H; Zhu GX; Lee KH
    Eur J Med Chem; 2016 Jun; 115():109-20. PubMed ID: 26994847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives.
    Zhu GX; Cheng PL; Goto M; Zhang N; Morris-Natschke SL; Hsieh KY; Yang GZ; Yang QR; Liu YQ; Chen HL; Zhang XS; Lee KH
    Bioorg Med Chem Lett; 2017 Apr; 27(8):1750-1753. PubMed ID: 28285912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents.
    Zi CT; Yang L; Xu FQ; Dong FW; Ma RJ; Li Y; Zhou J; Ding ZT; Jiang ZH; Hu JM
    Bioorg Med Chem Lett; 2019 Jan; 29(2):234-237. PubMed ID: 30509782
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, semisynthesis and potent cytotoxic activity of novel 10-fluorocamptothecin derivatives.
    Yang CJ; Song ZL; Goto M; Hsu PL; Zhang XS; Yang QR; Liu YQ; Wang MJ; Morris-Natschke SL; Shang XF; Lee KH
    Bioorg Med Chem Lett; 2017 Oct; 27(20):4694-4697. PubMed ID: 28927790
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and antineoplastic activity of novel 20(S)-acylthiourea derivatives of camptothecin.
    Yang CJ; Li B; Zhang ZJ; Gao JM; Wang MJ; Zhao XB; Song ZL; Liu YQ; Li H; Chen Y; Lee KH; Morris-Natschke SL; Xu C
    Eur J Med Chem; 2020 Feb; 187():111971. PubMed ID: 31881457
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of novel 20(S)-α-aminophosphonate derivatives of camptothecin as potent antitumor agents.
    Chen YY; Bai YP; Li B; Zhao XB; Yang CJ; Liu YQ; Gao JM; Guo J; Li C; Peng JW; Zhao ZM; Zhang ZJ; Xu CR
    Bioorg Chem; 2021 Sep; 114():105065. PubMed ID: 34174631
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and cytotoxicity of novel 20-O-linked homocamptothecin ester derivatives as potent topoisomerase I inhibitors.
    Li DZ; Wang CY; Liu RH; Wang YM; Ji TF; Li YR; Pan XD
    J Asian Nat Prod Res; 2013 Nov; 15(11):1179-88. PubMed ID: 24215541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and cytotoxic activity of novel spin-labeled rotenone derivatives.
    Liu YQ; Ohkoshi E; Li LH; Yang L; Lee KH
    Bioorg Med Chem Lett; 2012 Jan; 22(2):920-3. PubMed ID: 22204911
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
    Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
    Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents.
    Wang MJ; Liu YQ; Chang LC; Wang CY; Zhao YL; Zhao XB; Qian K; Nan X; Yang L; Yang XM; Hung HY; Yang JS; Kuo DH; Goto M; Morris-Natschke SL; Pan SL; Teng CM; Kuo SC; Wu TS; Wu YC; Lee KH
    J Med Chem; 2014 Jul; 57(14):6008-18. PubMed ID: 25003995
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives.
    Li WQ; Wang XL; Qian K; Liu YQ; Wang CY; Yang L; Tian J; Morris-Natschke SL; Zhou XW; Lee KH
    Bioorg Med Chem; 2013 Apr; 21(8):2363-2369. PubMed ID: 23490151
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel 7-substituted camptothecins with potent antitumor activity.
    Dallavalle S; Delsoldato T; Ferrari A; Merlini L; Penco S; Carenini N; Perego P; De Cesare M; Pratesi G; Zunino F
    J Med Chem; 2000 Oct; 43(21):3963-9. PubMed ID: 11052801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, Synthesis and Biological Activity of (20S,21S)-7-Cyclohexyl-21-fluorocamptothecin Carbamates as Potential Antitumor Agents.
    Ma H; Chen B; Wang Y; Wang C; Yao J; Zhang W; Miao Z
    Chem Biodivers; 2020 Jul; 17(7):e2000068. PubMed ID: 32342605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators.
    Al-Oudat BA; Alqudah MA; Audat SA; Al-Balas QA; El-Elimat T; Hassan MA; Frhat IN; Azaizeh MM
    Drug Des Devel Ther; 2019; 13():423-433. PubMed ID: 30774307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.