These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
225 related articles for article (PubMed ID: 25011481)
1. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. Zhang L; Nosak C; Sollazzo P; Odisho T; Volchuk A BMC Cell Biol; 2014 Jul; 15():29. PubMed ID: 25011481 [TBL] [Abstract][Full Text] [Related]
2. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin. Hartley T; Siva M; Lai E; Teodoro T; Zhang L; Volchuk A BMC Cell Biol; 2010 Jul; 11():59. PubMed ID: 20659334 [TBL] [Abstract][Full Text] [Related]
3. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells. Tiwari A; Schuiki I; Zhang L; Allister EM; Wheeler MB; Volchuk A J Cell Sci; 2013 May; 126(Pt 9):1962-8. PubMed ID: 23444373 [TBL] [Abstract][Full Text] [Related]
4. Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death. Blanc M; Habbouche L; Xiao P; Lebeaupin C; Janona M; Vaillant N; Irondelle M; Gilleron J; Murcy F; Rousseau D; Luci C; Barouillet T; Marchetti S; Lacas-Gervais S; Yvan-Charvet L; Gual P; Cardozo AK; Bailly-Maitre B Cell Death Dis; 2024 May; 15(5):334. PubMed ID: 38744890 [TBL] [Abstract][Full Text] [Related]
5. Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues. Zhang H; Nakajima S; Kato H; Gu L; Yoshitomi T; Nagai K; Shinmori H; Kokubo S; Kitamura M Br J Pharmacol; 2013 Oct; 170(4):822-34. PubMed ID: 23869584 [TBL] [Abstract][Full Text] [Related]
6. A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus Aspergillus fumigatus and Suggests Noncanonical Functions within the Pathway. Guirao-Abad JP; Weichert M; Albee A; Deck K; Askew DS mSphere; 2020 Oct; 5(5):. PubMed ID: 33087521 [TBL] [Abstract][Full Text] [Related]
7. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival. Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195 [TBL] [Abstract][Full Text] [Related]
8. Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells. Linssen MM; van Raalte DH; Toonen EJ; Alkema W; van der Zon GC; Dokter WH; Diamant M; Guigas B; Ouwens DM Cell Signal; 2011 Nov; 23(11):1708-15. PubMed ID: 21689745 [TBL] [Abstract][Full Text] [Related]
9. Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity. Zhang P; Su C; Jiang Z; Zheng C J Virol; 2017 Feb; 91(4):. PubMed ID: 27928013 [TBL] [Abstract][Full Text] [Related]
10. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Lipson KL; Fonseca SG; Ishigaki S; Nguyen LX; Foss E; Bortell R; Rossini AA; Urano F Cell Metab; 2006 Sep; 4(3):245-54. PubMed ID: 16950141 [TBL] [Abstract][Full Text] [Related]
11. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479 [TBL] [Abstract][Full Text] [Related]
12. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response. Sommerweiss D; Gorski T; Richter S; Garten A; Kiess W Biochem Biophys Res Commun; 2013 Nov; 441(4):770-6. PubMed ID: 24189472 [TBL] [Abstract][Full Text] [Related]
13. Pancreatic β-cells depend on basal expression of active ATF6α-p50 for cell survival even under nonstress conditions. Teodoro T; Odisho T; Sidorova E; Volchuk A Am J Physiol Cell Physiol; 2012 Apr; 302(7):C992-1003. PubMed ID: 22189555 [TBL] [Abstract][Full Text] [Related]
14. Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes. Herlea-Pana O; Eeda V; Undi RB; Lim HY; Wang W Front Endocrinol (Lausanne); 2021; 12():749879. PubMed ID: 34675883 [TBL] [Abstract][Full Text] [Related]
15. [Pathogenic Mechanism of Diabetes Development Due to Dysfunction of Unfolded Protein Response]. Tsuchiya Y; Saito M; Kohno K Yakugaku Zasshi; 2016; 136(6):817-25. PubMed ID: 27252061 [TBL] [Abstract][Full Text] [Related]
16. ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells. Odisho T; Zhang L; Volchuk A Exp Cell Res; 2015 Jan; 330(1):111-22. PubMed ID: 25447309 [TBL] [Abstract][Full Text] [Related]
17. IRE1-dependent activation of AMPK in response to nitric oxide. Meares GP; Hughes KJ; Naatz A; Papa FR; Urano F; Hansen PA; Benveniste EN; Corbett JA Mol Cell Biol; 2011 Nov; 31(21):4286-97. PubMed ID: 21896783 [TBL] [Abstract][Full Text] [Related]
18. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion. Cunningham CN; He K; Arunagiri A; Paton AW; Paton JC; Arvan P; Tsai B Diabetes; 2017 Mar; 66(3):741-753. PubMed ID: 28028074 [TBL] [Abstract][Full Text] [Related]