BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 25015099)

  • 21. Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.
    Phani NM; Adhikari P; Nagri SK; D'Souza SC; Satyamoorthy K; Rai PS
    PLoS One; 2016; 11(6):e0157364. PubMed ID: 27310578
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Association of TCF7L2 SNPs with age at onset of type 2 diabetes and proinsulin/insulin ratio but not with glucagon-like peptide 1.
    Silbernagel G; Renner W; Grammer TB; Hügl SR; Bertram J; Kleber ME; Hoffmann MM; Winkelmann BR; März W; Boehm BO
    Diabetes Metab Res Rev; 2011 Jul; 27(5):499-505. PubMed ID: 21384500
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.
    Kulzer JR; Stitzel ML; Morken MA; Huyghe JR; Fuchsberger C; Kuusisto J; Laakso M; Boehnke M; Collins FS; Mohlke KL
    Am J Hum Genet; 2014 Feb; 94(2):186-97. PubMed ID: 24439111
    [TBL] [Abstract][Full Text] [Related]  

  • 24. PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration.
    Zhu Y; Liu Q; Zhou Z; Ikeda Y
    Stem Cell Res Ther; 2017 Nov; 8(1):240. PubMed ID: 29096722
    [TBL] [Abstract][Full Text] [Related]  

  • 25. TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study.
    Stolerman ES; Manning AK; McAteer JB; Fox CS; Dupuis J; Meigs JB; Florez JC
    Diabetologia; 2009 Apr; 52(4):614-20. PubMed ID: 19183934
    [TBL] [Abstract][Full Text] [Related]  

  • 26. HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.
    Zhou Y; Oskolkov N; Shcherbina L; Ratti J; Kock KH; Su J; Martin B; Oskolkova MZ; Göransson O; Bacon J; Li W; Bucciarelli S; Cilio C; Brazma A; Thatcher B; Rung J; Wierup N; Renström E; Groop L; Hansson O
    Mol Cell Endocrinol; 2016 Jul; 430():138-45. PubMed ID: 26845344
    [TBL] [Abstract][Full Text] [Related]  

  • 27. ATF2 interacts with beta-cell-enriched transcription factors, MafA, Pdx1, and beta2, and activates insulin gene transcription.
    Han SI; Yasuda K; Kataoka K
    J Biol Chem; 2011 Mar; 286(12):10449-56. PubMed ID: 21278380
    [TBL] [Abstract][Full Text] [Related]  

  • 28. TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
    Loos RJ; Franks PW; Francis RW; Barroso I; Gribble FM; Savage DB; Ong KK; O'Rahilly S; Wareham NJ
    Diabetes; 2007 Jul; 56(7):1943-7. PubMed ID: 17416797
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.
    da Silva Xavier G; Mondragon A; Sun G; Chen L; McGinty JA; French PM; Rutter GA
    Diabetologia; 2012 Oct; 55(10):2667-2676. PubMed ID: 22717537
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.
    Masjkur J; Arps-Forker C; Poser SW; Nikolakopoulou P; Toutouna L; Chenna R; Chavakis T; Chatzigeorgiou A; Chen LS; Dubrovska A; Choudhary P; Uphues I; Mark M; Bornstein SR; Androutsellis-Theotokis A
    J Biol Chem; 2014 Dec; 289(51):35503-16. PubMed ID: 25371201
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Tissue-specific alternative splicing of TCF7L2.
    Prokunina-Olsson L; Welch C; Hansson O; Adhikari N; Scott LJ; Usher N; Tong M; Sprau A; Swift A; Bonnycastle LL; Erdos MR; He Z; Saxena R; Harmon B; Kotova O; Hoffman EP; Altshuler D; Groop L; Boehnke M; Collins FS; Hall JL
    Hum Mol Genet; 2009 Oct; 18(20):3795-804. PubMed ID: 19602480
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.
    González-Sánchez JL; Martínez-Larrad MT; Zabena C; Pérez-Barba M; Serrano-Ríos M
    Diabetologia; 2008 Nov; 51(11):1993-7. PubMed ID: 18712344
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The study of regulatory effects of Pdx-1, MafA and NeuroD1 on the activity of porcine insulin promoter and the expression of human islet amyloid polypeptide.
    Liu XD; Ruan JX; Xia JH; Yang SL; Fan JH; Li K
    Mol Cell Biochem; 2014 Sep; 394(1-2):59-66. PubMed ID: 24825179
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.
    Takamoto I; Kubota N; Nakaya K; Kumagai K; Hashimoto S; Kubota T; Inoue M; Kajiwara E; Katsuyama H; Obata A; Sakurai Y; Iwamoto M; Kitamura T; Ueki K; Kadowaki T
    Diabetologia; 2014 Mar; 57(3):542-53. PubMed ID: 24317852
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Loci of TCF7L2, HHEX and IDE on chromosome 10q and the susceptibility of their genetic polymorphisms to type 2 diabetes.
    Nordman S; Ostenson CG; Efendic S; Gu HF
    Exp Clin Endocrinol Diabetes; 2009 Apr; 117(4):186-90. PubMed ID: 19053027
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
    Schaffer AE; Taylor BL; Benthuysen JR; Liu J; Thorel F; Yuan W; Jiao Y; Kaestner KH; Herrera PL; Magnuson MA; May CL; Sander M
    PLoS Genet; 2013; 9(1):e1003274. PubMed ID: 23382704
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular biology. HNFs--linking the liver and pancreatic islets in diabetes.
    Kulkarni RN; Kahn CR
    Science; 2004 Feb; 303(5662):1311-2. PubMed ID: 14988544
    [No Abstract]   [Full Text] [Related]  

  • 38. Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes.
    Pang DX; Smith AJ; Humphries SE
    Nutr Metab Cardiovasc Dis; 2013 Jun; 23(6):550-6. PubMed ID: 22402060
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.
    Viñuela A; Varshney A; van de Bunt M; Prasad RB; Asplund O; Bennett A; Boehnke M; Brown AA; Erdos MR; Fadista J; Hansson O; Hatem G; Howald C; Iyengar AK; Johnson P; Krus U; MacDonald PE; Mahajan A; Manning Fox JE; Narisu N; Nylander V; Orchard P; Oskolkov N; Panousis NI; Payne A; Stitzel ML; Vadlamudi S; Welch R; Collins FS; Mohlke KL; Gloyn AL; Scott LJ; Dermitzakis ET; Groop L; Parker SCJ; McCarthy MI
    Nat Commun; 2020 Sep; 11(1):4912. PubMed ID: 32999275
    [TBL] [Abstract][Full Text] [Related]  

  • 40. MiR-205 is up-regulated in islets of diabetes-susceptible mice and targets the diabetes gene Tcf7l2.
    Ouni M; Gottmann P; Westholm E; Schwerbel K; Jähnert M; Stadion M; Rittig K; Vogel H; Schürmann A
    Acta Physiol (Oxf); 2021 Aug; 232(4):e13693. PubMed ID: 34028994
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.