94 related articles for article (PubMed ID: 25017035)
21. Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.
Hamuro Y; Coales SJ; Morrow JA; Molnar KS; Tuske SJ; Southern MR; Griffin PR
Protein Sci; 2006 Aug; 15(8):1883-92. PubMed ID: 16823031
[TBL] [Abstract][Full Text] [Related]
22. Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARγ agonists.
Obermoser V; Mauersberger R; Schuster D; Czifersky M; Lipova M; Siegl M; Kintscher U; Gust R
Eur J Med Chem; 2017 Jan; 126():590-603. PubMed ID: 27918994
[TBL] [Abstract][Full Text] [Related]
23. Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization.
Bernardes A; Souza PC; Muniz JR; Ricci CG; Ayers SD; Parekh NM; Godoy AS; Trivella DB; Reinach P; Webb P; Skaf MS; Polikarpov I
J Mol Biol; 2013 Aug; 425(16):2878-93. PubMed ID: 23707408
[TBL] [Abstract][Full Text] [Related]
24. Design, synthesis and evaluation of novel zwitterionic compounds as PPARα/γ dual agonists (1).
Shibata Y; Kagechika K; Yamaguchi M; Kubo H; Usui H
Bioorg Med Chem Lett; 2012 Dec; 22(23):7075-9. PubMed ID: 23084275
[TBL] [Abstract][Full Text] [Related]
25. Indenone derivatives: a novel template for peroxisome proliferator-activated receptor gamma (PPARgamma) agonists.
Ahn JH; Shin MS; Jung SH; Kang SK; Kim KR; Rhee SD; Jung WH; Yang SD; Kim SJ; Woo JR; Lee JH; Cheon HG; Kim SS
J Med Chem; 2006 Jul; 49(15):4781-4. PubMed ID: 16854085
[TBL] [Abstract][Full Text] [Related]
26. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation.
Ye F; Zhang ZS; Luo HB; Shen JH; Chen KX; Shen X; Jiang HL
Chembiochem; 2006 Jan; 7(1):74-82. PubMed ID: 16317783
[TBL] [Abstract][Full Text] [Related]
27. Design, synthesis, and evaluation of a novel series of alpha-substituted phenylpropanoic acid derivatives as human peroxisome proliferator-activated receptor (PPAR) alpha/delta dual agonists for the treatment of metabolic syndrome.
Kasuga J; Yamasaki D; Araya Y; Nakagawa A; Makishima M; Doi T; Hashimoto Y; Miyachi H
Bioorg Med Chem; 2006 Dec; 14(24):8405-14. PubMed ID: 16996742
[TBL] [Abstract][Full Text] [Related]
28. Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.
Deng G; Liu Z; Ye F; Luo X; Zhu W; Shen X; Liu H; Jiang H
Eur J Med Chem; 2008 Dec; 43(12):2699-716. PubMed ID: 18329752
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis, and structure-activity relationships of piperidine and dehydropiperidine carboxylic acids as novel, potent dual PPARalpha/gamma agonists.
Ye XY; Li YX; Farrelly D; Flynn N; Gu L; Locke KT; Lippy J; O'Malley K; Twamley C; Zhang L; Ryono DE; Zahler R; Hariharan N; Cheng PT
Bioorg Med Chem Lett; 2008 Jun; 18(12):3545-50. PubMed ID: 18511276
[TBL] [Abstract][Full Text] [Related]
30. Small-angle X-ray scattering studies on structures of an estrogen-related receptor alpha ligand binding domain and its complexes with ligands and coactivators.
Jin KS; Park JK; Yoon J; Rho Y; Kim JH; Kim EE; Ree M
J Phys Chem B; 2008 Aug; 112(32):9603-12. PubMed ID: 18646811
[TBL] [Abstract][Full Text] [Related]
31. Three-in-one agonists for PPAR-α, PPAR-γ, and PPAR-δ from traditional Chinese medicine.
Chen KC; Chang SS; Huang HJ; Lin TL; Wu YJ; Chen CY
J Biomol Struct Dyn; 2012; 30(6):662-83. PubMed ID: 22731403
[TBL] [Abstract][Full Text] [Related]
32. Synthesis of docosahexaenoic acid derivatives designed as novel PPARgamma agonists and antidiabetic agents.
Itoh T; Murota I; Yoshikai K; Yamada S; Yamamoto K
Bioorg Med Chem; 2006 Jan; 14(1):98-108. PubMed ID: 16198578
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar.
Ebdrup S; Pettersson I; Rasmussen HB; Deussen HJ; Frost Jensen A; Mortensen SB; Fleckner J; Pridal L; Nygaard L; Sauerberg P
J Med Chem; 2003 Apr; 46(8):1306-17. PubMed ID: 12672231
[TBL] [Abstract][Full Text] [Related]
34. Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists.
Lin CH; Peng YH; Coumar MS; Chittimalla SK; Liao CC; Lyn PC; Huang CC; Lien TW; Lin WH; Hsu JT; Cheng JH; Chen X; Wu JS; Chao YS; Lee HJ; Juo CG; Wu SY; Hsieh HP
J Med Chem; 2009 Apr; 52(8):2618-22. PubMed ID: 19301897
[TBL] [Abstract][Full Text] [Related]
35. Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists.
Lamotte Y; Faucher N; Sançon J; Pineau O; Sautet S; Fouchet MH; Beneton V; Tousaint JJ; Saintillan Y; Ancellin N; Nicodeme E; Grillot D; Martres P
Bioorg Med Chem Lett; 2014 Feb; 24(4):1098-103. PubMed ID: 24462665
[TBL] [Abstract][Full Text] [Related]
36. Structure-activity relationships and key structural feature of pyridyloxybenzene-acylsulfonamides as new, potent, and selective peroxisome proliferator-activated receptor (PPAR) γ Agonists.
Rikimaru K; Wakabayashi T; Abe H; Tawaraishi T; Imoto H; Yonemori J; Hirose H; Murase K; Matsuo T; Matsumoto M; Nomura C; Tsuge H; Arimura N; Kawakami K; Sakamoto J; Funami M; Mol CD; Snell GP; Bragstad KA; Sang BC; Dougan DR; Tanaka T; Katayama N; Horiguchi Y; Momose Y
Bioorg Med Chem; 2012 May; 20(10):3332-58. PubMed ID: 22503460
[TBL] [Abstract][Full Text] [Related]
37. Profiling the structural determinants for the selectivity of representative factor-Xa and thrombin inhibitors using combined ligand-based and structure-based approaches.
Bhunia SS; Roy KK; Saxena AK
J Chem Inf Model; 2011 Aug; 51(8):1966-85. PubMed ID: 21761917
[TBL] [Abstract][Full Text] [Related]
38. Design and synthesis of novel oxazole containing 1,3-dioxane-2-carboxylic acid derivatives as PPAR alpha/gamma dual agonists.
Pingali H; Jain M; Shah S; Makadia P; Zaware P; Goel A; Patel M; Giri S; Patel H; Patel P
Bioorg Med Chem; 2008 Aug; 16(15):7117-27. PubMed ID: 18625559
[TBL] [Abstract][Full Text] [Related]
39. Design and synthesis of marine fungal phthalide derivatives as PPAR-γ agonists.
Xiao B; Yin J; Park M; Liu J; Li JL; Kim EL; Hong J; Chung HY; Jung JH
Bioorg Med Chem; 2012 Aug; 20(16):4954-61. PubMed ID: 22819190
[TBL] [Abstract][Full Text] [Related]
40. Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands.
Seimandi M; Lemaire G; Pillon A; Perrin A; Carlavan I; Voegel JJ; Vignon F; Nicolas JC; Balaguer P
Anal Biochem; 2005 Sep; 344(1):8-15. PubMed ID: 16038868
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
