173 related articles for article (PubMed ID: 25019332)
1. Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.
Ge HM; Huang T; Rudolf JD; Lohman JR; Huang SX; Guo X; Shen B
Org Lett; 2014 Aug; 16(15):3958-61. PubMed ID: 25019332
[TBL] [Abstract][Full Text] [Related]
2. Iterative type I polyketide synthases for enediyne core biosynthesis.
Horsman GP; Van Lanen SG; Shen B
Methods Enzymol; 2009; 459():97-112. PubMed ID: 19362637
[TBL] [Abstract][Full Text] [Related]
3. Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes.
Horsman GP; Chen Y; Thorson JS; Shen B
Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11331-5. PubMed ID: 20534556
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis.
Kong R; Goh LP; Liew CW; Ho QS; Murugan E; Li B; Tang K; Liang ZX
J Am Chem Soc; 2008 Jul; 130(26):8142-3. PubMed ID: 18529057
[TBL] [Abstract][Full Text] [Related]
5. Iterative type I polyketide synthases involved in enediyne natural product biosynthesis.
Chen X; Ji R; Jiang X; Yang R; Liu F; Xin Y
IUBMB Life; 2014 Sep; 66(9):587-95. PubMed ID: 25278375
[TBL] [Abstract][Full Text] [Related]
6. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.
Bhardwaj M; Cui Z; Daniel Hankore E; Moonschi FH; Saghaeiannejad Esfahani H; Kalkreuter E; Gui C; Yang D; Phillips GN; Thorson JS; Shen B; Van Lanen SG
Proc Natl Acad Sci U S A; 2023 Feb; 120(9):e2220468120. PubMed ID: 36802426
[TBL] [Abstract][Full Text] [Related]
7. Biochemical determination of enzyme-bound metabolites: preferential accumulation of a programmed octaketide on the enediyne polyketide synthase CalE8.
Belecki K; Townsend CA
J Am Chem Soc; 2013 Sep; 135(38):14339-48. PubMed ID: 24041368
[TBL] [Abstract][Full Text] [Related]
8. Studying a Bottleneck of Multimodular Polyketide Synthase Processing: the Polyketide Structure-Dependent Performance of Ketoreductase Domains.
Schröder M; Roß T; Hemmerling F; Hahn F
ACS Chem Biol; 2022 May; 17(5):1030-1037. PubMed ID: 35412301
[TBL] [Abstract][Full Text] [Related]
9. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures.
Belecki K; Crawford JM; Townsend CA
J Am Chem Soc; 2009 Sep; 131(35):12564-6. PubMed ID: 19689130
[TBL] [Abstract][Full Text] [Related]
10. Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis.
Sun H; Kong R; Zhu D; Lu M; Ji Q; Liew CW; Lescar J; Zhong G; Liang ZX
Chem Commun (Camb); 2009 Dec; (47):7399-401. PubMed ID: 20024241
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis.
Liew CW; Nilsson M; Chen MW; Sun H; Cornvik T; Liang ZX; Lescar J
J Biol Chem; 2012 Jun; 287(27):23203-15. PubMed ID: 22589546
[TBL] [Abstract][Full Text] [Related]
12. Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.
Xie X; Garg A; Khosla C; Cane DE
J Am Chem Soc; 2017 Mar; 139(8):3283-3292. PubMed ID: 28157306
[TBL] [Abstract][Full Text] [Related]
13. Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain.
Soehano I; Yang L; Ding F; Sun H; Low ZJ; Liu X; Liang ZX
Org Biomol Chem; 2014 Nov; 12(42):8542-9. PubMed ID: 25238086
[TBL] [Abstract][Full Text] [Related]
14. Biosynthesis of enediyne antitumor antibiotics.
Van Lanen SG; Shen B
Curr Top Med Chem; 2008; 8(6):448-59. PubMed ID: 18397168
[TBL] [Abstract][Full Text] [Related]
15. Biochemical analysis of the substrate specificity of the beta-ketoacyl-acyl carrier protein synthase domain of module 2 of the erythromycin polyketide synthase.
Wu J; Kinoshita K; Khosla C; Cane DE
Biochemistry; 2004 Dec; 43(51):16301-10. PubMed ID: 15610024
[TBL] [Abstract][Full Text] [Related]
16. Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.
Annaval T; Rudolf JD; Chang CY; Lohman JR; Kim Y; Bigelow L; Jedrzejczak R; Babnigg G; Joachimiak A; Phillips GN; Shen B
ACS Omega; 2017 Aug; 2(8):5159-5169. PubMed ID: 28884166
[TBL] [Abstract][Full Text] [Related]
17. A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis.
Cohen DR; Townsend CA
Nat Chem; 2018 Feb; 10(2):231-236. PubMed ID: 29359752
[TBL] [Abstract][Full Text] [Related]
18. Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase.
Wu J; Zaleski TJ; Valenzano C; Khosla C; Cane DE
J Am Chem Soc; 2005 Dec; 127(49):17393-404. PubMed ID: 16332089
[TBL] [Abstract][Full Text] [Related]
19. A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones.
Meoded RA; Ueoka R; Helfrich EJN; Jensen K; Magnus N; Piechulla B; Piel J
Angew Chem Int Ed Engl; 2018 Sep; 57(36):11644-11648. PubMed ID: 29898240
[TBL] [Abstract][Full Text] [Related]
20. Structure and catalytic mechanism of the thioesterase CalE7 in enediyne biosynthesis.
Kotaka M; Kong R; Qureshi I; Ho QS; Sun H; Liew CW; Goh LP; Cheung P; Mu Y; Lescar J; Liang ZX
J Biol Chem; 2009 Jun; 284(23):15739-49. PubMed ID: 19357082
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]