BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

356 related articles for article (PubMed ID: 25022204)

  • 1. Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells.
    Defaux J; Antoine M; Logé C; Le Borgne M; Schuster T; Seipelt I; Aicher B; Teifel M; Günther E; Gerlach M; Marchand P
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3748-52. PubMed ID: 25022204
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of 7-aryl-substituted (1,5-naphthyridin-4-yl)ureas as aurora kinase inhibitors.
    Defaux J; Antoine M; Le Borgne M; Schuster T; Seipelt I; Aicher B; Teifel M; Günther E; Gerlach M; Marchand P
    ChemMedChem; 2014 Jan; 9(1):217-32. PubMed ID: 24273104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity.
    Li J; Hu H; Lang Q; Zhang H; Huang Q; Wu Y; Yu L
    Eur J Med Chem; 2013 Jul; 65():151-7. PubMed ID: 23707920
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of 4-aminoquinazoline--urea derivatives as Aurora kinase inhibitors with antiproliferative activity.
    Cai J; Li L; Hong KH; Wu X; Chen J; Wang P; Cao M; Zong X; Ji M
    Bioorg Med Chem; 2014 Nov; 22(21):5813-23. PubMed ID: 25270403
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of potent 1,2,4-trisubstituted imidazolinone derivatives with dual p38αMAPK and ERK1/2 inhibitory activity.
    Awadallah FM; Abou-Seri SM; Abdulla MM; Georgey HH
    Eur J Med Chem; 2015 Apr; 94():397-404. PubMed ID: 25778995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of novel benzoxazole analogs as Aurora B kinase inhibitors.
    An Y; Lee E; Yu Y; Yun J; Lee MY; Kang JS; Kim WY; Jeon R
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3067-3072. PubMed ID: 27209235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and evaluation of novel diaryl urea derivatives as potential antitumor agents.
    Lu C; Tang K; Li Y; Li P; Lin Z; Yin D; Chen X; Huang H
    Eur J Med Chem; 2014 Apr; 77():351-60. PubMed ID: 24675135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of nitroaryl urea derivatives with antiproliferative properties.
    Wróbel TM; Kiełbus M; Kaczor AA; Kryštof V; Karczmarzyk Z; Wysocki W; Fruziński A; Król SK; Grabarska A; Stepulak A; Matosiuk D
    J Enzyme Inhib Med Chem; 2016 Aug; 31(4):608-18. PubMed ID: 26114307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of N-aryl-N'-pyrimidin-4-yl ureas as irreversible L858R/T790M mutant selective epidermal growth factor receptor inhibitors.
    Zhou F; Zhang L; Jin Y; Liu W; Cheng P; He X; Xie J; Shen S; Lei J; Ji H; Hu Y; Liu Y; Cui Y; Lv Q; Lan J
    Bioorg Med Chem Lett; 2018 Apr; 28(7):1257-1261. PubMed ID: 29534926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New diarylamides and diarylureas possessing 8-amino(acetamido)quinoline scaffold: synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studies.
    Koh EJ; El-Gamal MI; Oh CH; Lee SH; Sim T; Kim G; Choi HS; Hong JH; Lee SG; Yoo KH
    Eur J Med Chem; 2013; 70():10-21. PubMed ID: 24128410
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors.
    Bo YX; Xiang R; Xu Y; Hao SY; Wang XR; Chen SW
    Bioorg Med Chem; 2020 Mar; 28(5):115351. PubMed ID: 32035750
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of novel N
    Qi B; Yang Y; He H; Yue X; Zhou Y; Zhou X; Chen Y; Liu M; Zhang A; Wei F
    Eur J Med Chem; 2018 Feb; 146():368-380. PubMed ID: 29407963
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.
    Song D; Park Y; Yoon J; Aman W; Hah JM; Ryu JS
    Bioorg Med Chem; 2014 Sep; 22(17):4855-66. PubMed ID: 25042560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.
    Chang Hsu Y; Ke YY; Shiao HY; Lee CC; Lin WH; Chen CH; Yen KJ; Hsu JT; Chang C; Hsieh HP
    ChemMedChem; 2014 May; 9(5):953-61. PubMed ID: 24665000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and optimization of novel phenyldiazepine and pyridodiazepine based Aurora kinase inhibitors.
    Tamizharasan N; Gajendran C; Kristam R; Sulochana SP; Sivanandhan D; Mullangi R; Mathivathanan L; Hallur G; Suresh P
    Bioorg Chem; 2020 Jun; 99():103800. PubMed ID: 32283344
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 4-arylamido 3-methyl isoxazole derivatives as novel FMS kinase inhibitors.
    Im D; Jung K; Yang S; Aman W; Hah JM
    Eur J Med Chem; 2015 Sep; 102():600-10. PubMed ID: 26318067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
    Qi B; Xu X; Yang Y; He H; Yue X
    Bioorg Med Chem; 2019 Sep; 27(17):3825-3835. PubMed ID: 31307762
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer.
    Dokla EME; Abdel-Aziz AK; Milik SN; Mahmoud AH; Saadeldin MK; McPhillie MJ; Minucci S; Abouzid KAM
    Bioorg Chem; 2021 Dec; 117():105451. PubMed ID: 34736137
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 5-(2-(phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one derivatives as potent Mnk2 inhibitors: synthesis, SAR analysis and biological evaluation.
    Diab S; Teo T; Kumarasiri M; Li P; Yu M; Lam F; Basnet SK; Sykes MJ; Albrecht H; Milne R; Wang S
    ChemMedChem; 2014 May; 9(5):962-72. PubMed ID: 24677692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-Raf(V600E) and C-Raf kinase inhibitory activities.
    El-Damasy AK; Lee JH; Seo SH; Cho NC; Pae AN; Keum G
    Eur J Med Chem; 2016 Jun; 115():201-16. PubMed ID: 27017549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.