663 related articles for article (PubMed ID: 25024225)
1. Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Lee JJ; Perera RM; Wang H; Wu DC; Liu XS; Han S; Fitamant J; Jones PD; Ghanta KS; Kawano S; Nagle JM; Deshpande V; Boucher Y; Kato T; Chen JK; Willmann JK; Bardeesy N; Beachy PA
Proc Natl Acad Sci U S A; 2014 Jul; 111(30):E3091-100. PubMed ID: 25024225
[TBL] [Abstract][Full Text] [Related]
2. Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
Ji Z; Mei FC; Xie J; Cheng X
J Biol Chem; 2007 May; 282(19):14048-55. PubMed ID: 17353198
[TBL] [Abstract][Full Text] [Related]
3. Paracrine sonic hedgehog signaling derived from tumor epithelial cells: a key regulator in the pancreatic tumor microenvironment.
Li X; Ma Q; Duan W; Liu H; Xu H; Wu E
Crit Rev Eukaryot Gene Expr; 2012; 22(2):97-108. PubMed ID: 22856428
[TBL] [Abstract][Full Text] [Related]
4. Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
Pasca di Magliano M; Sekine S; Ermilov A; Ferris J; Dlugosz AA; Hebrok M
Genes Dev; 2006 Nov; 20(22):3161-73. PubMed ID: 17114586
[TBL] [Abstract][Full Text] [Related]
5. Hedgehog signaling and pancreatic tumor development.
Lauth M; Toftgård R
Adv Cancer Res; 2011; 110():1-17. PubMed ID: 21704226
[TBL] [Abstract][Full Text] [Related]
6. Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse.
Bangs FK; Miller P; O'Neill E
Dis Model Mech; 2020 Jul; 13(7):. PubMed ID: 32571902
[TBL] [Abstract][Full Text] [Related]
7. Hedgehog signaling promotes angiogenesis directly and indirectly in pancreatic cancer.
Bausch D; Fritz S; Bolm L; Wellner UF; Fernandez-Del-Castillo C; Warshaw AL; Thayer SP; Liss AS
Angiogenesis; 2020 Aug; 23(3):479-492. PubMed ID: 32444947
[TBL] [Abstract][Full Text] [Related]
8. Gli2 protein expression level is a feasible marker of ligand-dependent hedgehog activation in pancreatic neoplasms.
Sugiyama Y; Sasajima J; Mizukami Y; Koizumi K; Kawamoto T; Ono Y; Karasaki H; Tanabe H; Fujiya M; Kohgo Y
Pol J Pathol; 2016 Jun; 67(2):136-44. PubMed ID: 27543868
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.
Hwang RF; Moore TT; Hattersley MM; Scarpitti M; Yang B; Devereaux E; Ramachandran V; Arumugam T; Ji B; Logsdon CD; Brown JL; Godin R
Mol Cancer Res; 2012 Sep; 10(9):1147-57. PubMed ID: 22859707
[TBL] [Abstract][Full Text] [Related]
10. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Nolan-Stevaux O; Lau J; Truitt ML; Chu GC; Hebrok M; Fernández-Zapico ME; Hanahan D
Genes Dev; 2009 Jan; 23(1):24-36. PubMed ID: 19136624
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development.
Chu NJ; Anders RA; Fertig EJ; Cao M; Hopkins AC; Keenan BP; Popovic A; Armstrong TD; Jaffee EM; Zimmerman JW
Cancer Prev Res (Phila); 2020 Jul; 13(7):569-582. PubMed ID: 32409593
[TBL] [Abstract][Full Text] [Related]
12. Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.
Damhofer H; Medema JP; Veenstra VL; Badea L; Popescu I; Roelink H; Bijlsma MF
Mol Oncol; 2013 Dec; 7(6):1031-42. PubMed ID: 23998958
[TBL] [Abstract][Full Text] [Related]
13. Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Rhim AD; Oberstein PE; Thomas DH; Mirek ET; Palermo CF; Sastra SA; Dekleva EN; Saunders T; Becerra CP; Tattersall IW; Westphalen CB; Kitajewski J; Fernandez-Barrena MG; Fernandez-Zapico ME; Iacobuzio-Donahue C; Olive KP; Stanger BZ
Cancer Cell; 2014 Jun; 25(6):735-47. PubMed ID: 24856585
[TBL] [Abstract][Full Text] [Related]
14. Critical role of oncogenic KRAS in pancreatic cancer (Review).
Liu J; Ji S; Liang C; Qin Y; Jin K; Liang D; Xu W; Shi S; Zhang B; Liu L; Liu C; Xu J; Ni Q; Yu X
Mol Med Rep; 2016 Jun; 13(6):4943-9. PubMed ID: 27121414
[TBL] [Abstract][Full Text] [Related]
15. Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics.
Layeghi-Ghalehsoukhteh S; Pal Choudhuri S; Ocal O; Zolghadri Y; Pashkov V; Niederstrasser H; Posner BA; Kantheti HS; Azevedo-Pouly AC; Huang H; Girard L; MacDonald RJ; Brekken RA; Wilkie TM
Sci Rep; 2020 Nov; 10(1):20662. PubMed ID: 33244070
[TBL] [Abstract][Full Text] [Related]
16. Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Qiu W; Sahin F; Iacobuzio-Donahue CA; Garcia-Carracedo D; Wang WM; Kuo CY; Chen D; Arking DE; Lowy AM; Hruban RH; Remotti HE; Su GH
Oncotarget; 2011 Nov; 2(11):862-73. PubMed ID: 22113502
[TBL] [Abstract][Full Text] [Related]
17. N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer.
Su Y; Li J; Witkiewicz AK; Brennan D; Neill T; Talarico J; Radice GL
Oncogene; 2012 Oct; 31(41):4484-9. PubMed ID: 22158044
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer.
Onishi H; Kai M; Odate S; Iwasaki H; Morifuji Y; Ogino T; Morisaki T; Nakashima Y; Katano M
Cancer Sci; 2011 Jun; 102(6):1144-50. PubMed ID: 21338440
[TBL] [Abstract][Full Text] [Related]
19. Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Mazur PK; Einwächter H; Lee M; Sipos B; Nakhai H; Rad R; Zimber-Strobl U; Strobl LJ; Radtke F; Klöppel G; Schmid RM; Siveke JT
Proc Natl Acad Sci U S A; 2010 Jul; 107(30):13438-43. PubMed ID: 20624967
[TBL] [Abstract][Full Text] [Related]
20. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma.
von Figura G; Fukuda A; Roy N; Liku ME; Morris Iv JP; Kim GE; Russ HA; Firpo MA; Mulvihill SJ; Dawson DW; Ferrer J; Mueller WF; Busch A; Hertel KJ; Hebrok M
Nat Cell Biol; 2014 Mar; 16(3):255-67. PubMed ID: 24561622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
