These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Clinical pattern, mutations and in vitro residual activity in 33 patients with severe 5, 10 methylenetetrahydrofolate reductase (MTHFR) deficiency. Huemer M; Mulder-Bleile R; Burda P; Froese DS; Suormala T; Zeev BB; Chinnery PF; Dionisi-Vici C; Dobbelaere D; Gökcay G; Demirkol M; Häberle J; Lossos A; Mengel E; Morris AA; Niezen-Koning KE; Plecko B; Parini R; Rokicki D; Schiff M; Schimmel M; Sewell AC; Sperl W; Spiekerkoetter U; Steinmann B; Taddeucci G; Trejo-Gabriel-Galán JM; Trefz F; Tsuji M; Vilaseca MA; von Kleist-Retzow JC; Walker V; Zeman J; Baumgartner MR; Fowler B J Inherit Metab Dis; 2016 Jan; 39(1):115-24. PubMed ID: 26025547 [TBL] [Abstract][Full Text] [Related]
3. Early treatment using betaine and methionine for a neonate with MTHFR deficiency. Nishimoto E; Ito Y; Sakakibara T; Nishikubo T Pediatr Int; 2019 Dec; 61(12):1265-1266. PubMed ID: 31782227 [No Abstract] [Full Text] [Related]
4. A founder mutation causing a severe methylenetetrahydrofolate reductase (MTHFR) deficiency in Bukharian Jews. Ben-Shachar S; Zvi T; Rolfs A; Breda Klobus A; Yaron Y; Bar-Shira A; Orr-Urtreger A Mol Genet Metab; 2012 Nov; 107(3):608-10. PubMed ID: 22947400 [TBL] [Abstract][Full Text] [Related]
5. Adult-onset severe methylenetetrahydrofolate reductase deficiency characterized by reversible spastic paraplegia with a novel mutation. Lin N; Jiang N; Dai Y; Gao J; Wang L Neurol Sci; 2016 Oct; 37(10):1735-7. PubMed ID: 27118298 [No Abstract] [Full Text] [Related]
6. Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy. D'Aco KE; Bearden D; Watkins D; Hyland K; Rosenblatt DS; Ficicioglu C Pediatr Neurol; 2014 Aug; 51(2):266-70. PubMed ID: 25079578 [TBL] [Abstract][Full Text] [Related]
8. Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia. Lossos A; Teltsh O; Milman T; Meiner V; Rozen R; Leclerc D; Schwahn BC; Karp N; Rosenblatt DS; Watkins D; Shaag A; Korman SH; Heyman SN; Gal A; Newman JP; Steiner-Birmanns B; Abramsky O; Kohn Y JAMA Neurol; 2014 Jul; 71(7):901-4. PubMed ID: 24797679 [TBL] [Abstract][Full Text] [Related]
9. Survival and psychomotor development with early betaine treatment in patients with severe methylenetetrahydrofolate reductase deficiency. Diekman EF; de Koning TJ; Verhoeven-Duif NM; Rovers MM; van Hasselt PM JAMA Neurol; 2014 Feb; 71(2):188-94. PubMed ID: 24323041 [TBL] [Abstract][Full Text] [Related]
10. [Methylenetetrahydrofolate Reductase deficiency and anesthesia: importance of a detailed preoperative evaluation]. Santos CDSE; Grayson BE Braz J Anesthesiol; 2019; 69(6):637-638. PubMed ID: 31796301 [No Abstract] [Full Text] [Related]
11. Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency. Froese DS; Huemer M; Suormala T; Burda P; Coelho D; Guéant JL; Landolt MA; Kožich V; Fowler B; Baumgartner MR Hum Mutat; 2016 May; 37(5):427-38. PubMed ID: 26872964 [TBL] [Abstract][Full Text] [Related]
12. Determination and interpretation of MTHFR gene mutations in gynecology and internal medicine. Undas A; Chojnowski K; Klukowska A; Łętowska M; Mital A; Młynarski W; Musiał J; Podolak-Dawidziak M; Sąsiadek M; Treliński J; Urasiński T; Windyga J; Zdziarska J; Zawilska K Pol Arch Intern Med; 2019 Oct; 129(10):728-732. PubMed ID: 31670725 [No Abstract] [Full Text] [Related]
13. [Posterior-predominant leukoencephalopathy which was caused by methylenetetrahydrofolate reductase deficiency and successfully treated with folic acid]. Tamura A; Sasaki R; Kagawa K; Nakatani K; Osaka H; Tomimoto H Rinsho Shinkeigaku; 2014; 54(3):200-6. PubMed ID: 24705833 [TBL] [Abstract][Full Text] [Related]
14. Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: molecular genetic and enzymatic characterization of 76 patients. Burda P; Schäfer A; Suormala T; Rummel T; Bürer C; Heuberger D; Frapolli M; Giunta C; Sokolová J; Vlášková H; Kožich V; Koch HG; Fowler B; Froese DS; Baumgartner MR Hum Mutat; 2015 Jun; 36(6):611-21. PubMed ID: 25736335 [TBL] [Abstract][Full Text] [Related]
15. Severe methylenetetrahydrofolate reductase (MTHFR) deficiency: a case report of nonclassical homocystinuria. Bishop L; Kanoff R; Charnas L; Krenzel C; Berry SA; Schimmenti LA J Child Neurol; 2008 Jul; 23(7):823-8. PubMed ID: 18658082 [TBL] [Abstract][Full Text] [Related]
16. The 1316T>C missenses mutation in MTHFR contributes to MTHFR deficiency by targeting MTHFR to proteasome degradation. Liu X; Li Y; Wang M; Wang X; Zhang L; Peng T; Liang W; Wang Z; Lu H Aging (Albany NY); 2020 Dec; 13(1):1176-1185. PubMed ID: 33290257 [TBL] [Abstract][Full Text] [Related]
17. Stability of DNA methylation patterns in mouse spermatogonia under conditions of MTHFR deficiency and methionine supplementation. Garner JL; Niles KM; McGraw S; Yeh JR; Cushnie DW; Hermo L; Nagano MC; Trasler JM Biol Reprod; 2013 Nov; 89(5):125. PubMed ID: 24048573 [TBL] [Abstract][Full Text] [Related]
18. Thrombotic events after starting exogenous testosterone in men with previously undiagnosed familial thrombophilia. Glueck CJ; Goldenberg N; Budhani S; Lotner D; Abuchaibe C; Gowda M; Nayar T; Khan N; Wang P Transl Res; 2011 Oct; 158(4):225-34. PubMed ID: 21925119 [TBL] [Abstract][Full Text] [Related]
19. Methylenetetrahydrofolate reductase deficiency (homocystinuria type II) as a rare cause of rapidly progressive tetraspasticity and psychosis in a previously healthy adult. Birnbaum T; Blom HJ; Prokisch H; Hartig M; Klopstock T J Neurol; 2008 Nov; 255(11):1845-6. PubMed ID: 18854913 [No Abstract] [Full Text] [Related]
20. Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant. Meadows DN; Pyzik M; Wu Q; Torre S; Gros P; Vidal SM; Rozen R Hum Mutat; 2014 May; 35(5):594-600. PubMed ID: 24616178 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]