230 related articles for article (PubMed ID: 25025768)
1. Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.
Cukras S; Morffy N; Ohn T; Kee Y
PLoS One; 2014; 9(7):e101844. PubMed ID: 25025768
[TBL] [Abstract][Full Text] [Related]
2. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
Zhou W; Xu J; Tan M; Li H; Li H; Wei W; Sun Y
Mol Cell; 2018 Jun; 70(6):1008-1024.e6. PubMed ID: 29932898
[TBL] [Abstract][Full Text] [Related]
3. Targeting neddylation E2s: a novel therapeutic strategy in cancer.
Zheng YC; Guo YJ; Wang B; Wang C; Mamun MAA; Gao Y; Liu HM
J Hematol Oncol; 2021 Apr; 14(1):57. PubMed ID: 33827629
[TBL] [Abstract][Full Text] [Related]
4. Knockdown of Nedd8‑conjugating enzyme UBE2M suppresses the proliferation and induces the apoptosis of intrahepatic cholangiocarcinoma cells.
Zhao B; Gao C; Shi D; Mao J; Zhao J; Guo L; Guo J; Jiao Z
Oncol Rep; 2019 Dec; 42(6):2670-2679. PubMed ID: 31545502
[TBL] [Abstract][Full Text] [Related]
5. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification.
Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C
Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067
[TBL] [Abstract][Full Text] [Related]
6. Neddylation-CRLs regulate the functions of Treg immune cells.
Wu D; Sun Y
Bioessays; 2023 Apr; 45(4):e2200222. PubMed ID: 36709423
[TBL] [Abstract][Full Text] [Related]
7. Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases.
Tan CY; Hagen T
Int J Biochem Cell Biol; 2013 Jul; 45(7):1489-98. PubMed ID: 23597704
[TBL] [Abstract][Full Text] [Related]
8. Micafungin: A promising inhibitor of UBE2M in cancer cell growth suppression.
Mamun MAA; Liu S; Zhao L; Zhao L; Li ZR; Shen D; Zheng Y; Zheng YC; Liu HM
Eur J Med Chem; 2023 Nov; 260():115732. PubMed ID: 37651876
[TBL] [Abstract][Full Text] [Related]
9. Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
Shibata E; Abbas T; Huang X; Wohlschlegel JA; Dutta A
Mol Cell Biol; 2011 Aug; 31(15):3136-45. PubMed ID: 21628527
[TBL] [Abstract][Full Text] [Related]
10. The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness.
Wu D; Li H; Liu M; Qin J; Sun Y
Nat Commun; 2022 May; 13(1):3021. PubMed ID: 35641500
[TBL] [Abstract][Full Text] [Related]
11. Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Ma T; Song Q; Cheng B; Guo E; Wang X; Li M; Dai M; Li S; Feng S; Yu B
Bioorg Chem; 2024 Mar; 144():107142. PubMed ID: 38280358
[TBL] [Abstract][Full Text] [Related]
12. NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.
Zhao X; Jiang L; Hu D; Tang Y; Zhao G; Du X; Luo S; Tang W
Exp Cell Res; 2021 Jun; 403(2):112614. PubMed ID: 33905671
[TBL] [Abstract][Full Text] [Related]
13. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer.
Li L; Kang J; Zhang W; Cai L; Wang S; Liang Y; Jiang Y; Liu X; Zhang Y; Ruan H; Chen G; Wang M; Jia L
EBioMedicine; 2019 Jul; 45():81-91. PubMed ID: 31208947
[TBL] [Abstract][Full Text] [Related]
14. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
Lan H; Tang Z; Jin H; Sun Y
Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
[TBL] [Abstract][Full Text] [Related]
15. Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.
Chew EH; Poobalasingam T; Hawkey CJ; Hagen T
Cell Signal; 2007 May; 19(5):1071-80. PubMed ID: 17254749
[TBL] [Abstract][Full Text] [Related]
16. NEDD8-conjugating enzyme E2s: critical targets for cancer therapy.
Zhou L; Lin X; Zhu J; Zhang L; Chen S; Yang H; Jia L; Chen B
Cell Death Discov; 2023 Jan; 9(1):23. PubMed ID: 36690633
[TBL] [Abstract][Full Text] [Related]
17. RNF111-dependent neddylation activates DNA damage-induced ubiquitination.
Ma T; Chen Y; Zhang F; Yang CY; Wang S; Yu X
Mol Cell; 2013 Mar; 49(5):897-907. PubMed ID: 23394999
[TBL] [Abstract][Full Text] [Related]
18. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma.
Zhang Y; Shi CC; Zhang HP; Li GQ; Li SS
Oncotarget; 2016 Jul; 7(29):45263-45274. PubMed ID: 27223074
[TBL] [Abstract][Full Text] [Related]
19. Adenovirus oncoprotein E4orf6 triggers Cullin5 neddylation to activate the CLR5 E3 ligase for p53 degradation.
Guo H; Shen S; Li Y; Bi R; Zhang N; Zheng W; Deng Y; Yang Y; Yu XF; Wang C; Wei W
Biochem Biophys Res Commun; 2019 Sep; 516(4):1242-1247. PubMed ID: 31301771
[TBL] [Abstract][Full Text] [Related]
20. The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
Dohmann EM; Levesque MP; De Veylder L; Reichardt I; Jürgens G; Schmid M; Schwechheimer C
Development; 2008 Jun; 135(11):2013-22. PubMed ID: 18434413
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]