183 related articles for article (PubMed ID: 25025853)
1. Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
Romagnoli R; Baraldi PG; Salvador MK; Prencipe F; Bertolasi V; Cancellieri M; Brancale A; Hamel E; Castagliuolo I; Consolaro F; Porcù E; Basso G; Viola G
J Med Chem; 2014 Aug; 57(15):6795-808. PubMed ID: 25025853
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Wang F; Yang Z; Liu Y; Ma L; Wu Y; He L; Shao M; Yu K; Wu W; Pu Y; Nie C; Chen L
Bioorg Med Chem; 2015 Jul; 23(13):3337-50. PubMed ID: 25937236
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
Romagnoli R; Baraldi PG; Cruz-Lopez O; Lopez Cara C; Carrion MD; Brancale A; Hamel E; Chen L; Bortolozzi R; Basso G; Viola G
J Med Chem; 2010 May; 53(10):4248-58. PubMed ID: 20420439
[TBL] [Abstract][Full Text] [Related]
4. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
[TBL] [Abstract][Full Text] [Related]
5. Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
Romagnoli R; Baraldi PG; Salvador MK; Preti D; Aghazadeh Tabrizi M; Brancale A; Fu XH; Li J; Zhang SZ; Hamel E; Bortolozzi R; Porcù E; Basso G; Viola G
J Med Chem; 2012 Jun; 55(11):5433-45. PubMed ID: 22578111
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
Prasad B; Lakshma Nayak V; Srikanth PS; Baig MF; Subba Reddy NV; Babu KS; Kamal A
Bioorg Chem; 2019 Mar; 83():535-548. PubMed ID: 30472555
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R; Baraldi PG; Sarkar T; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Hsieh HP; Hamel E
J Med Chem; 2008 Mar; 51(5):1464-8. PubMed ID: 18260616
[TBL] [Abstract][Full Text] [Related]
9. Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes.
Lee HY; Chang CY; Lai MJ; Chuang HY; Kuo CC; Chang CY; Chang JY; Liou JP
Bioorg Med Chem; 2015 Aug; 23(15):4230-4236. PubMed ID: 26160020
[TBL] [Abstract][Full Text] [Related]
10. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Romagnoli R; Prencipe F; Oliva P; Baraldi S; Baraldi PG; Brancale A; Ferla S; Hamel E; Bortolozzi R; Viola G
Bioorg Chem; 2018 Oct; 80():361-374. PubMed ID: 29986184
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agents.
Gangjee A; Zhao Y; Hamel E; Westbrook C; Mooberry SL
J Med Chem; 2011 Sep; 54(17):6151-5. PubMed ID: 21786793
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
Yang F; Chen L; Lai JM; Jian XE; Lv DX; Yuan LL; Liu YX; Liang FT; Zheng XL; Li XL; Wei LY; You WW; Zhao PL
Bioorg Med Chem Lett; 2021 Apr; 38():127880. PubMed ID: 33636303
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationships of N-methyl-5,6,7-trimethoxylindoles as novel antimitotic and vascular disrupting agents.
Zhao DG; Chen J; Du YR; Ma YY; Chen YX; Gao K; Hu BR
J Med Chem; 2013 Feb; 56(4):1467-77. PubMed ID: 23360369
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
15. New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
La Regina G; Bai R; Coluccia A; Famiglini V; Pelliccia S; Passacantilli S; Mazzoccoli C; Ruggieri V; Sisinni L; Bolognesi A; Rensen WM; Miele A; Nalli M; Alfonsi R; Di Marcotullio L; Gulino A; Brancale A; Novellino E; Dondio G; Vultaggio S; Varasi M; Mercurio C; Hamel E; Lavia P; Silvestri R
J Med Chem; 2014 Aug; 57(15):6531-52. PubMed ID: 25025991
[TBL] [Abstract][Full Text] [Related]
16. Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
Romagnoli R; Baraldi PG; Lopez-Cara C; Preti D; Aghazadeh Tabrizi M; Balzarini J; Bassetto M; Brancale A; Fu XH; Gao Y; Li J; Zhang SZ; Hamel E; Bortolozzi R; Basso G; Viola G
J Med Chem; 2013 Nov; 56(22):9296-309. PubMed ID: 24164557
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
Kamal A; Shaik B; Nayak VL; Nagaraju B; Kapure JS; Shaheer Malik M; Shaik TB; Prasad B
Bioorg Med Chem; 2014 Oct; 22(19):5155-67. PubMed ID: 25192811
[TBL] [Abstract][Full Text] [Related]
18. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
Lee HY; Chang JY; Nien CY; Kuo CC; Shih KH; Wu CH; Chang CY; Lai WY; Liou JP
J Med Chem; 2011 Dec; 54(24):8517-25. PubMed ID: 22060033
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.
Huang L; Liu M; Man S; Ma D; Feng D; Sun Z; Guan Q; Zuo D; Wu Y; Zhang W; Bao K
Eur J Med Chem; 2020 Jan; 186():111846. PubMed ID: 31740055
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]