214 related articles for article (PubMed ID: 25025991)
1. New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
La Regina G; Bai R; Coluccia A; Famiglini V; Pelliccia S; Passacantilli S; Mazzoccoli C; Ruggieri V; Sisinni L; Bolognesi A; Rensen WM; Miele A; Nalli M; Alfonsi R; Di Marcotullio L; Gulino A; Brancale A; Novellino E; Dondio G; Vultaggio S; Varasi M; Mercurio C; Hamel E; Lavia P; Silvestri R
J Med Chem; 2014 Aug; 57(15):6531-52. PubMed ID: 25025991
[TBL] [Abstract][Full Text] [Related]
2. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
[TBL] [Abstract][Full Text] [Related]
3. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
[TBL] [Abstract][Full Text] [Related]
4. Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
La Regina G; Bai R; Rensen WM; Di Cesare E; Coluccia A; Piscitelli F; Famiglini V; Reggio A; Nalli M; Pelliccia S; Da Pozzo E; Costa B; Granata I; Porta A; Maresca B; Soriani A; Iannitto ML; Santoni A; Li J; Miranda Cona M; Chen F; Ni Y; Brancale A; Dondio G; Vultaggio S; Varasi M; Mercurio C; Martini C; Hamel E; Lavia P; Novellino E; Silvestri R
J Med Chem; 2013 Jan; 56(1):123-49. PubMed ID: 23214452
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
Kamal A; Rao MP; Das P; Swapna P; Polepalli S; Nimbarte VD; Mullagiri K; Kovvuri J; Jain N
ChemMedChem; 2014 Jul; 9(7):1463-75. PubMed ID: 24715721
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
Wang G; Peng F; Cao D; Yang Z; Han X; Liu J; Wu W; He L; Ma L; Chen J; Sang Y; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2013 Nov; 21(21):6844-54. PubMed ID: 23993668
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
8. New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors.
La Regina G; Bai R; Coluccia A; Naccarato V; Famiglini V; Nalli M; Masci D; Verrico A; Rovella P; Mazzoccoli C; Da Pozzo E; Cavallini C; Martini C; Vultaggio S; Dondio G; Varasi M; Mercurio C; Hamel E; Lavia P; Silvestri R
Eur J Med Chem; 2018 May; 152():283-297. PubMed ID: 29730191
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
Zhai M; Wang L; Liu S; Wang L; Yan P; Wang J; Zhang J; Guo H; Guan Q; Bao K; Wu Y; Zhang W
Eur J Med Chem; 2018 Aug; 156():137-147. PubMed ID: 30006160
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.
Khelifi I; Naret T; Renko D; Hamze A; Bernadat G; Bignon J; Lenoir C; Dubois J; Brion JD; Provot O; Alami M
Eur J Med Chem; 2017 Feb; 127():1025-1034. PubMed ID: 28166995
[TBL] [Abstract][Full Text] [Related]
11. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
[TBL] [Abstract][Full Text] [Related]
12. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
Bioorg Chem; 2020 Jan; 95():103565. PubMed ID: 31927336
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
Moussa SA; A Osman EE; Eid NM; Abou-Seri SM; El Moghazy SM
Future Med Chem; 2018 Aug; 10(16):1907-1924. PubMed ID: 29966433
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
Romagnoli R; Baraldi PG; Salvador MK; Prencipe F; Bertolasi V; Cancellieri M; Brancale A; Hamel E; Castagliuolo I; Consolaro F; Porcù E; Basso G; Viola G
J Med Chem; 2014 Aug; 57(15):6795-808. PubMed ID: 25025853
[TBL] [Abstract][Full Text] [Related]
16. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.
Zhu H; Li W; Shuai W; Liu Y; Yang L; Tan Y; Zheng T; Yao H; Xu J; Zhu Z; Yang DH; Chen ZS; Xu S
Eur J Med Chem; 2021 Apr; 216():113316. PubMed ID: 33676300
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
20. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
