These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 25027205)

  • 1. Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancer.
    Centuori SM; Martinez JD
    Dig Dis Sci; 2014 Oct; 59(10):2367-80. PubMed ID: 25027205
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ursodeoxycholic acid shows antineoplastic effects in bile duct cancer cells via apoptosis induction; p53 activation; and EGFR-ERK, COX-2, and PI3K-AKT pathway inhibition.
    Lee J; Hong EM; Kim JH; Kim JH; Jung JH; Park SW; Koh DH; Jang HJ
    Mol Biol Rep; 2021 Sep; 48(9):6231-6240. PubMed ID: 34392440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells.
    Im E; Martinez JD
    J Nutr; 2004 Feb; 134(2):483-6. PubMed ID: 14747693
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enrichment of the more hydrophilic bile acid ursodeoxycholic acid in the fecal water-soluble fraction after feeding to rats with colon polyps.
    Batta AK; Salen G; Holubec H; Brasitus TA; Alberts D; Earnest DL
    Cancer Res; 1998 Apr; 58(8):1684-7. PubMed ID: 9563483
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.
    Powell AA; Akare S; Qi W; Herzer P; Jean-Louis S; Feldman RA; Martinez JD
    BMC Cancer; 2006 Sep; 6():219. PubMed ID: 16948850
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L; Studer E; Leach K; McKinstry R; Gupta S; Decker R; Kukreja R; Valerie K; Nagarkatti P; El Deiry W; Molkentin J; Schmidt-Ullrich R; Fisher PB; Grant S; Hylemon PB; Dent P
    Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
    Lee HY; Crawley S; Hokari R; Kwon S; Kim YS
    Int J Oncol; 2010 Apr; 36(4):941-53. PubMed ID: 20198339
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
    Qiao L; Yacoub A; Studer E; Gupta S; Pei XY; Grant S; Hylemon PB; Dent P
    Hepatology; 2002 Apr; 35(4):779-89. PubMed ID: 11915023
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells.
    Shah SA; Volkov Y; Arfin Q; Abdel-Latif MM; Kelleher D
    Int J Cancer; 2006 Feb; 118(3):532-9. PubMed ID: 16106402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.
    Byrne AM; Foran E; Sharma R; Davies A; Mahon C; O'Sullivan J; O'Donoghue D; Kelleher D; Long A
    Carcinogenesis; 2010 Apr; 31(4):737-44. PubMed ID: 20093383
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The bile acids, deoxycholic acid and ursodeoxycholic acid, regulate colonic epithelial wound healing.
    Mroz MS; Lajczak NK; Goggins BJ; Keely S; Keely SJ
    Am J Physiol Gastrointest Liver Physiol; 2018 Mar; 314(3):G378-G387. PubMed ID: 29351391
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bile acids are multifunctional modulators of the Barrett's carcinogenesis.
    Burnat G; Majka J; Konturek PC
    J Physiol Pharmacol; 2010 Apr; 61(2):185-92. PubMed ID: 20436219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic epithelial cells.
    Lajczak NK; Saint-Criq V; O'Dwyer AM; Perino A; Adorini L; Schoonjans K; Keely SJ
    FASEB J; 2017 Sep; 31(9):3848-3857. PubMed ID: 28487283
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.
    Qiao D; Gaitonde SV; Qi W; Martinez JD
    Carcinogenesis; 2001 Jun; 22(6):957-64. PubMed ID: 11375905
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein.
    Khare S; Mustafi R; Cerda S; Yuan W; Jagadeeswaran S; Dougherty U; Tretiakova M; Samarel A; Cohen G; Wang J; Moore C; Wali R; Holgren C; Joseph L; Fichera A; Li YC; Bissonnette M
    Nutr Cancer; 2008; 60(3):389-400. PubMed ID: 18444174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing effects of bile acids deoxycholic acid and ursodeoxycholic acid on signal transduction pathways in oesophageal cancer cells.
    Abdel-Latif MM; Inoue H; Reynolds JV
    Eur J Cancer Prev; 2016 Sep; 25(5):368-79. PubMed ID: 26378497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells.
    Centuori SM; Gomes CJ; Trujillo J; Borg J; Brownlee J; Putnam CW; Martinez JD
    Biochim Biophys Acta; 2016 Jul; 1861(7):663-70. PubMed ID: 27086143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of bile acids on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced aberrant crypt foci and DNA adduct formation in the rat colon.
    Ueyama Y; Monden Y; He XB; Lin CX; Momen MA; Mimura S; Umemoto A
    J Exp Clin Cancer Res; 2002 Dec; 21(4):577-83. PubMed ID: 12636105
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
    Gupta S; Natarajan R; Payne SG; Studer EJ; Spiegel S; Dent P; Hylemon PB
    J Biol Chem; 2004 Feb; 279(7):5821-8. PubMed ID: 14660582
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.
    Lew JL; Zhao A; Yu J; Huang L; De Pedro N; Peláez F; Wright SD; Cui J
    J Biol Chem; 2004 Mar; 279(10):8856-61. PubMed ID: 14684751
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.