BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 25027467)

  • 1. Evaluation of inhibitory effects of benzothiazole and 3-amino-benzothiazolium derivatives on DNA topoisomerase II by molecular modeling studies.
    Aki-Yalcin E; Ertan-Bolelli T; Taskin-Tok T; Ozturk O; Ataei S; Ozen C; Yildiz I; Yalcin I
    SAR QSAR Environ Res; 2014; 25(8):637-49. PubMed ID: 25027467
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indenoindolone derivatives as topoisomerase II-inhibiting anticancer agents.
    Kashyap M; Kandekar S; Baviskar AT; Das D; Preet R; Mohapatra P; Satapathy SR; Siddharth S; Guchhait SK; Kundu CN; Banerjee UC
    Bioorg Med Chem Lett; 2013 Feb; 23(4):934-8. PubMed ID: 23321564
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives.
    Na Y; Nam JM
    Bioorg Med Chem Lett; 2011 Jan; 21(1):211-4. PubMed ID: 21115246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
    Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
    Karki R; Park C; Jun KY; Jee JG; Lee JH; Thapa P; Kadayat TM; Kwon Y; Lee ES
    Eur J Med Chem; 2014 Sep; 84():555-65. PubMed ID: 25062006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor.
    Jun KY; Kwon H; Park SE; Lee E; Karki R; Thapa P; Lee JH; Lee ES; Kwon Y
    Eur J Med Chem; 2014 Jun; 80():428-38. PubMed ID: 24796883
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity.
    Choi SJ; Park HJ; Lee SK; Kim SW; Han G; Choo HY
    Bioorg Med Chem; 2006 Feb; 14(4):1229-35. PubMed ID: 16242334
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking.
    Taskin T; Yilmaz S; Yildiz I; Yalcin I; Aki E
    SAR QSAR Environ Res; 2012; 23(3-4):345-55. PubMed ID: 22490049
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking studies, synthesis, characterization of some novel oxazine substituted 9-anilinoacridine derivatives and evaluation for their antioxidant and anticancer activities as topoisomerase II inhibitors.
    Kalirajan R; Kulshrestha V; Sankar S; Jubie S
    Eur J Med Chem; 2012 Oct; 56():217-24. PubMed ID: 22982526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insight into Mechanism of Action of Anticancer Benzazoles.
    Ozturk O; Aki-Yalcin E; Yalcin I; Grifitth R
    Curr Top Med Chem; 2020; 20(23):2056-2069. PubMed ID: 32814529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
    Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of mono- and disubstituted 1H-pyrazolo[3,4]pyrimidines and 9H-purines as catalytic inhibitors of human DNA topoisomerase IIα.
    Pogorelčnik B; Brvar M; Žegura B; Filipič M; Solmajer T; Perdih A
    ChemMedChem; 2015 Feb; 10(2):345-59. PubMed ID: 25522133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
    Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
    Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of Interactions of Selected Olivacine Derivatives with DNA and Topoisomerase II.
    Tylińska B; Dobosz A; Spychała J; Cwynar-Zając Ł; Czyżnikowska Ż; Kuźniarski A; Gębarowski T
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
    Baviskar AT; Madaan C; Preet R; Mohapatra P; Jain V; Agarwal A; Guchhait SK; Kundu CN; Banerjee UC; Bharatam PV
    J Med Chem; 2011 Jul; 54(14):5013-30. PubMed ID: 21644529
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid-DACH conjugate: comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies.
    Arjmand F; Yousuf I; Hadda Tb; Toupet L
    Eur J Med Chem; 2014 Jun; 81():76-88. PubMed ID: 24826817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study.
    Basnet A; Thapa P; Karki R; Choi H; Choi JH; Yun M; Jeong BS; Jahng Y; Na Y; Cho WJ; Kwon Y; Lee CS; Lee ES
    Bioorg Med Chem Lett; 2010 Jan; 20(1):42-7. PubMed ID: 19954977
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
    Jun KY; Lee EY; Jung MJ; Lee OH; Lee ES; Park Choo HY; Na Y; Kwon Y
    Eur J Med Chem; 2011 Jun; 46(6):1964-71. PubMed ID: 21419530
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L; Marzaro G; Ferrarese A; Gia O; Chilin A
    Eur J Med Chem; 2014 Apr; 77():103-9. PubMed ID: 24631729
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
    Kamal A; Suresh P; Ramaiah MJ; Srinivasa Reddy T; Kapavarapu RK; Rao BN; Imthiajali S; Lakshminarayan Reddy T; Pushpavalli SN; Shankaraiah N; Pal-Bhadra M
    Bioorg Med Chem; 2013 Sep; 21(17):5198-208. PubMed ID: 23849207
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.