These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 25033318)

  • 1. Synthesis of methyl 2-cyano-3,12-dioxo-18β-olean-1,9(11)-dien-30-oate analogues to determine the active groups for inhibiting cell growth and inducing apoptosis in leukemia cells.
    Li X; Wang Y; Gao Y; Li L; Guo X; Liu D; Jing Y; Zhao L
    Org Biomol Chem; 2014 Sep; 12(34):6706-16. PubMed ID: 25033318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of c-FLIP, XIAP and Mcl-1 protein as well as depletion of reduced glutathione contribute to the apoptosis induction of glycyrrhetinic acid derivatives in leukemia cells.
    Song D; Gao Y; Wang R; Liu D; Zhao L; Jing Y
    Cancer Biol Ther; 2010 Jan; 9(2):96-108. PubMed ID: 19949310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HDAC and Ku70 axis- an effective target for apoptosis induction by a new 2-cyano-3-oxo-1,9-dien glycyrrhetinic acid analogue.
    Gong P; Li K; Li Y; Liu D; Zhao L; Jing Y
    Cell Death Dis; 2018 May; 9(6):623. PubMed ID: 29795376
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ethacrynic acid oxadiazole analogs induce apoptosis in malignant hematologic cells through downregulation of Mcl-1 and c-FLIP, which was attenuated by GSTP1-1.
    Liu G; Wang R; Wang Y; Li P; Zhao G; Zhao L; Jing Y
    Mol Cancer Ther; 2013 Sep; 12(9):1837-47. PubMed ID: 23804706
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methyl 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate is a peroxisome proliferator-activated receptor-gamma agonist that induces receptor-independent apoptosis in LNCaP prostate cancer cells.
    Papineni S; Chintharlapalli S; Safe S
    Mol Pharmacol; 2008 Feb; 73(2):553-65. PubMed ID: 17989348
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells.
    Chintharlapalli S; Papineni S; Abdelrahim M; Abudayyeh A; Jutooru I; Chadalapaka G; Wu F; Mertens-Talcott S; Vanderlaag K; Cho SD; Smith R; Safe S
    Int J Cancer; 2009 Oct; 125(8):1965-74. PubMed ID: 19582879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The synthesis of 18beta-glycyrrhetinic acid derivatives which have increased antiproliferative and apoptotic effects in leukemia cells.
    Liu D; Song D; Guo G; Wang R; Lv J; Jing Y; Zhao L
    Bioorg Med Chem; 2007 Aug; 15(16):5432-9. PubMed ID: 17566745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A 18β-glycyrrhetinic acid conjugate with Vorinostat degrades HDAC3 and HDAC6 with improved antitumor effects.
    Huang M; Xie X; Gong P; Wei Y; Du H; Xu Y; Xu Q; Jing Y; Zhao L
    Eur J Med Chem; 2020 Feb; 188():111991. PubMed ID: 31883490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antitumor effects of novel 18β-glycyrrhetinic acid derivatives featuring an exocyclic α,β-unsaturated carbonyl moiety in ring A.
    Huang M; Gong P; Wang Y; Xie X; Ma Z; Xu Q; Liu D; Jing Y; Zhao L
    Bioorg Chem; 2020 Oct; 103():104187. PubMed ID: 32890994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells.
    Li Y; Wang R; Ma E; Deng Y; Wang X; Xiao J; Jing Y
    Anticancer Drugs; 2010 Apr; 21(4):389-400. PubMed ID: 20110807
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and pro-apoptotic activity of novel glycyrrhetinic acid derivatives.
    Logashenko EB; Salomatina OV; Markov AV; Korchagina DV; Salakhutdinov NF; Tolstikov GA; Vlassov VV; Zenkova MA
    Chembiochem; 2011 Mar; 12(5):784-94. PubMed ID: 21328513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells.
    Chintharlapalli S; Papineni S; Jutooru I; McAlees A; Safe S
    Mol Cancer Ther; 2007 May; 6(5):1588-98. PubMed ID: 17513608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The synthesis of glycyrrhetinic acid derivatives containing a nitrogen heterocycle and their antiproliferative effects in human leukemia cells.
    Gao Y; Guo X; Li X; Liu D; Song D; Xu Y; Sun M; Jing Y; Zhao L
    Molecules; 2010 Jun; 15(6):4439-49. PubMed ID: 20657452
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP.
    Siegelin MD; Gaiser T; Siegelin Y
    Neurochem Int; 2009 Nov; 55(6):423-30. PubMed ID: 19409438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of triazole linked glycosylated 18β-glycyrrhetinic acid derivatives as anticancer agents.
    Parida PK; Sau A; Ghosh T; Jana K; Biswas K; Raha S; Misra AK
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3865-8. PubMed ID: 25027936
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of novel heterocyclic ring-fused 18β-glycyrrhetinic acid derivatives with antitumor and antimetastatic activity.
    Gao C; Dai FJ; Cui HW; Peng SH; He Y; Wang X; Yi ZF; Qiu WW
    Chem Biol Drug Des; 2014 Aug; 84(2):223-33. PubMed ID: 24612785
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Semisynthetic ursolic acid fluorolactone derivatives inhibit growth with induction of p21(waf1) and induce apoptosis with upregulation of NOXA and downregulation of c-FLIP in cancer cells.
    Leal AS; Wang R; Salvador JA; Jing Y
    ChemMedChem; 2012 Sep; 7(9):1635-46. PubMed ID: 22807348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 18beta-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity.
    Lee CS; Kim YJ; Lee MS; Han ES; Lee SJ
    Life Sci; 2008 Sep; 83(13-14):481-9. PubMed ID: 18721818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activity of some antitumor active derivatives from glycyrrhetinic acid.
    Csuk R; Schwarz S; Kluge R; Ströhl D
    Eur J Med Chem; 2010 Dec; 45(12):5718-23. PubMed ID: 20884085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel cyano derivative of 11-keto-β-boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells.
    Khan S; Kaur R; Shah BA; Malik F; Kumar A; Bhushan S; Jain SK; Taneja SC; Singh J
    Mol Carcinog; 2012 Sep; 51(9):679-95. PubMed ID: 21751262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.