These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Diabetes: Protective role of autophagy in pancreatic β cells. Osório J Nat Rev Endocrinol; 2014 Oct; 10(10):575. PubMed ID: 25112233 [No Abstract] [Full Text] [Related]
4. Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes. Kim J; Cheon H; Jeong YT; Quan W; Kim KH; Cho JM; Lim YM; Oh SH; Jin SM; Kim JH; Lee MK; Kim S; Komatsu M; Kang SW; Lee MS J Clin Invest; 2014 Aug; 124(8):3311-24. PubMed ID: 25036705 [TBL] [Abstract][Full Text] [Related]
5. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Costes S; Gurlo T; Rivera JF; Butler PC Autophagy; 2014 Jun; 10(6):1004-14. PubMed ID: 24879150 [TBL] [Abstract][Full Text] [Related]
6. Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy. Shigihara N; Fukunaka A; Hara A; Komiya K; Honda A; Uchida T; Abe H; Toyofuku Y; Tamaki M; Ogihara T; Miyatsuka T; Hiddinga HJ; Sakagashira S; Koike M; Uchiyama Y; Yoshimori T; Eberhardt NL; Fujitani Y; Watada H J Clin Invest; 2014 Aug; 124(8):3634-44. PubMed ID: 25036706 [TBL] [Abstract][Full Text] [Related]
7. Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice. Lin CY; Gurlo T; Kayed R; Butler AE; Haataja L; Glabe CG; Butler PC Diabetes; 2007 May; 56(5):1324-32. PubMed ID: 17353506 [TBL] [Abstract][Full Text] [Related]
8. Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus. Jeong HR; An SS Clin Interv Aging; 2015; 10():1873-9. PubMed ID: 26604727 [TBL] [Abstract][Full Text] [Related]
9. CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis. Gurlo T; Rivera JF; Butler AE; Cory M; Hoang J; Costes S; Butler PC Mol Endocrinol; 2016 Apr; 30(4):446-54. PubMed ID: 26900721 [TBL] [Abstract][Full Text] [Related]
10. Intravenous immunoglobulin improves glucose control and β-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers. Zhang Y; Yu XL; Zhu J; Liu SY; Liu XM; Dong QX; Chai JQ; Liu RT Int Immunopharmacol; 2018 Jan; 54():145-152. PubMed ID: 29145032 [TBL] [Abstract][Full Text] [Related]
11. Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions. Rivera JF; Gurlo T; Daval M; Huang CJ; Matveyenko AV; Butler PC; Costes S Cell Death Differ; 2011 Mar; 18(3):415-26. PubMed ID: 20814419 [TBL] [Abstract][Full Text] [Related]
12. β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. Costes S; Huang CJ; Gurlo T; Daval M; Matveyenko AV; Rizza RA; Butler AE; Butler PC Diabetes; 2011 Jan; 60(1):227-38. PubMed ID: 20980462 [TBL] [Abstract][Full Text] [Related]
13. Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes. Matveyenko AV; Butler PC ILAR J; 2006; 47(3):225-33. PubMed ID: 16804197 [TBL] [Abstract][Full Text] [Related]
16. Islet amyloid polypeptide in pancreatic islets from type 2 diabetic subjects. Tomita T Islets; 2012; 4(3):223-32. PubMed ID: 22847497 [TBL] [Abstract][Full Text] [Related]
17. Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway. Gurlo T; Ryazantsev S; Huang CJ; Yeh MW; Reber HA; Hines OJ; O'Brien TD; Glabe CG; Butler PC Am J Pathol; 2010 Feb; 176(2):861-9. PubMed ID: 20042670 [TBL] [Abstract][Full Text] [Related]
18. Islet amyloid toxicity: From genesis to counteracting mechanisms. Marmentini C; Branco RCS; Boschero AC; Kurauti MA J Cell Physiol; 2022 Feb; 237(2):1119-1142. PubMed ID: 34636428 [TBL] [Abstract][Full Text] [Related]
19. Role of islet β cell autophagy in the pathogenesis of diabetes. Lee MS Trends Endocrinol Metab; 2014 Dec; 25(12):620-7. PubMed ID: 25242548 [TBL] [Abstract][Full Text] [Related]
20. Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate. Rulifson IC; Cao P; Miao L; Kopecky D; Huang L; White RD; Samayoa K; Gardner J; Wu X; Chen K; Tsuruda T; Homann O; Baribault H; Yamane H; Carlson T; Wiltzius J; Li Y PLoS One; 2016; 11(2):e0147254. PubMed ID: 26840340 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]