BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 25040785)

  • 1. mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity.
    Mizunuma M; Neumann-Haefelin E; Moroz N; Li Y; Blackwell TK
    Aging Cell; 2014 Oct; 13(5):869-78. PubMed ID: 25040785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A non-canonical role for the C. elegans dosage compensation complex in growth and metabolic regulation downstream of TOR complex 2.
    Webster CM; Wu L; Douglas D; Soukas AA
    Development; 2013 Sep; 140(17):3601-12. PubMed ID: 23884442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development.
    Ruf V; Holzem C; Peyman T; Walz G; Blackwell TK; Neumann-Haefelin E
    Dev Biol; 2013 Dec; 384(2):214-27. PubMed ID: 23973804
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans.
    Gatsi R; Schulze B; Rodríguez-Palero MJ; Hernando-Rodríguez B; Baumeister R; Artal-Sanz M
    PLoS One; 2014; 9(9):e107671. PubMed ID: 25265021
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation.
    Chen AT; Guo C; Dumas KJ; Ashrafi K; Hu PJ
    Aging Cell; 2013 Oct; 12(5):932-40. PubMed ID: 23786484
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
    Lamming DW; Mihaylova MM; Katajisto P; Baar EL; Yilmaz OH; Hutchins A; Gultekin Y; Gaither R; Sabatini DM
    Aging Cell; 2014 Oct; 13(5):911-7. PubMed ID: 25059582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans.
    Aspernig H; Heimbucher T; Qi W; Gangurde D; Curic S; Yan Y; Donner von Gromoff E; Baumeister R; Thien A
    Cell Rep; 2019 Nov; 29(6):1399-1409.e5. PubMed ID: 31693882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.
    Das R; Melo JA; Thondamal M; Morton EA; Cornwell AB; Crick B; Kim JH; Swartz EW; Lamitina T; Douglas PM; Samuelson AV
    PLoS Genet; 2017 Oct; 13(10):e1007038. PubMed ID: 29036198
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO.
    Robida-Stubbs S; Glover-Cutter K; Lamming DW; Mizunuma M; Narasimhan SD; Neumann-Haefelin E; Sabatini DM; Blackwell TK
    Cell Metab; 2012 May; 15(5):713-24. PubMed ID: 22560223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: role of mTORC2/SGK1 pathway.
    He J; Qi D; Wang DX; Deng W; Ye Y; Feng LH; Zhu T; Zhao Y; Zhang CR
    Exp Cell Res; 2015 Feb; 331(1):164-175. PubMed ID: 25265063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport.
    Dowen RH; Breen PC; Tullius T; Conery AL; Ruvkun G
    Genes Dev; 2016 Jul; 30(13):1515-28. PubMed ID: 27401555
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase.
    Mori S; Nada S; Kimura H; Tajima S; Takahashi Y; Kitamura A; Oneyama C; Okada M
    PLoS One; 2014; 9(2):e88891. PubMed ID: 24558442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.
    Hertweck M; Göbel C; Baumeister R
    Dev Cell; 2004 Apr; 6(4):577-88. PubMed ID: 15068796
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.
    Soukas AA; Kane EA; Carr CE; Melo JA; Ruvkun G
    Genes Dev; 2009 Feb; 23(4):496-511. PubMed ID: 19240135
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in
    Li Y; Finkbeiner S; Ganner A; Gerber J; Klein M; Grafe M; Kandzia J; Thien A; Thedieck K; Breves G; Jank T; Baumeister R; Walz G; Neumann-Haefelin E
    Oncotarget; 2018 Feb; 9(11):9581-9595. PubMed ID: 29515755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prohibitin depletion extends lifespan of a TORC2/SGK-1 mutant through autophagy and the mitochondrial UPR.
    de la Cruz-Ruiz P; Hernando-Rodríguez B; Pérez-Jiménez MM; Rodríguez-Palero MJ; Martínez-Bueno MD; Pla A; Gatsi R; Artal-Sanz M
    Aging Cell; 2021 May; 20(5):e13359. PubMed ID: 33939875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.