BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

637 related articles for article (PubMed ID: 25043204)

  • 1. Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide.
    Colombo E; Di Dario M; Capitolo E; Chaabane L; Newcombe J; Martino G; Farina C
    Ann Neurol; 2014 Sep; 76(3):325-37. PubMed ID: 25043204
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation.
    Choi JW; Gardell SE; Herr DR; Rivera R; Lee CW; Noguchi K; Teo ST; Yung YC; Lu M; Kennedy G; Chun J
    Proc Natl Acad Sci U S A; 2011 Jan; 108(2):751-6. PubMed ID: 21177428
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration.
    Colombo E; Bassani C; De Angelis A; Ruffini F; Ottoboni L; Comi G; Martino G; Farina C
    Front Immunol; 2020; 11():635. PubMed ID: 32322257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis.
    Chun J; Hartung HP
    Clin Neuropharmacol; 2010; 33(2):91-101. PubMed ID: 20061941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Functionally Defined
    Groves A; Kihara Y; Jonnalagadda D; Rivera R; Kennedy G; Mayford M; Chun J
    eNeuro; 2018; 5(5):. PubMed ID: 30255127
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Fingolimod therapy in multiple sclerosis--the issue of the pathomechanism].
    Tar L; Vécsei L
    Ideggyogy Sz; 2012 Mar; 65(3-4):83-100. PubMed ID: 23136726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy.
    Groves A; Kihara Y; Chun J
    J Neurol Sci; 2013 May; 328(1-2):9-18. PubMed ID: 23518370
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.
    Imeri F; Fallegger D; Zivkovic A; Schwalm S; Enzmann G; Blankenbach K; Meyer zu Heringdorf D; Homann T; Kleuser B; Pfeilschifter J; Engelhardt B; Stark H; Huwiler A
    Neuropharmacology; 2014 Oct; 85():314-27. PubMed ID: 24863045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a selective S1P1 receptor agonist, Syl930, as a potential therapeutic agent for autoimmune encephalitis.
    Jin J; Hu J; Zhou W; Wang X; Xiao Q; Xue N; Yin D; Chen X
    Biochem Pharmacol; 2014 Jul; 90(1):50-61. PubMed ID: 24780445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system.
    Brinkmann V
    Br J Pharmacol; 2009 Nov; 158(5):1173-82. PubMed ID: 19814729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors.
    Osinde M; Mullershausen F; Dev KK
    Neuropharmacology; 2007 Apr; 52(5):1210-8. PubMed ID: 17379261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
    Mullershausen F; Craveiro LM; Shin Y; Cortes-Cros M; Bassilana F; Osinde M; Wishart WL; Guerini D; Thallmair M; Schwab ME; Sivasankaran R; Seuwen K; Dev KK
    J Neurochem; 2007 Aug; 102(4):1151-61. PubMed ID: 17488279
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Basic mechanisms of action of fingolimod in relation to multiple sclerosis].
    García-Merino JA; Sánchez AJ
    Rev Neurol; 2012 Jul; 55(1):31-7. PubMed ID: 22718407
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis.
    Chiba K; Adachi K
    Future Med Chem; 2012 Apr; 4(6):771-81. PubMed ID: 22530640
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of berberine on a murine model of multiple sclerosis and the SPHK1/S1P signaling pathway.
    Luo J; Chen R; Zeng S; Yu J; Jiang G; Wang L; Qin X
    Biochem Biophys Res Commun; 2017 Aug; 490(3):927-932. PubMed ID: 28655617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clinical immunology of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in multiple sclerosis.
    Mehling M; Johnson TA; Antel J; Kappos L; Bar-Or A
    Neurology; 2011 Feb; 76(8 Suppl 3):S20-7. PubMed ID: 21339487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses.
    Papadopoulos D; Rundle J; Patel R; Marshall I; Stretton J; Eaton R; Richardson JC; Gonzalez MI; Philpott KL; Reynolds R
    J Neurosci Res; 2010 Feb; 88(2):346-59. PubMed ID: 19658199
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions.
    Van Doorn R; Van Horssen J; Verzijl D; Witte M; Ronken E; Van Het Hof B; Lakeman K; Dijkstra CD; Van Der Valk P; Reijerkerk A; Alewijnse AE; Peters SL; De Vries HE
    Glia; 2010 Sep; 58(12):1465-76. PubMed ID: 20648639
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Morpholino Analogues of Fingolimod as Novel and Selective S1P
    Stepanovska B; Zivkovic A; Enzmann G; Tietz S; Homann T; Kleuser B; Engelhardt B; Stark H; Huwiler A
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32899717
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis.
    Cohen JA; Chun J
    Ann Neurol; 2011 May; 69(5):759-77. PubMed ID: 21520239
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.