206 related articles for article (PubMed ID: 2504483)
1. Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N,N',N''-triethylenethiophosphoramide.
Teicher BA; Waxman DJ; Holden SA; Wang YY; Clarke L; Alvarez Sotomayor E; Jones SM; Frei E
Cancer Res; 1989 Sep; 49(18):4996-5001. PubMed ID: 2504483
[TBL] [Abstract][Full Text] [Related]
2. Interaction of N,N',N''-triethylenethiophosphoramide and N,N',N''-triethylenephosphoramide with cellular DNA.
Cohen NA; Egorin MJ; Snyder SW; Ashar B; Wietharn BE; Pan SS; Ross DD; Hilton J
Cancer Res; 1991 Aug; 51(16):4360-6. PubMed ID: 1714342
[TBL] [Abstract][Full Text] [Related]
3. Modulation of alkylating agents by etanidazole and Fluosol-DA/carbogen in the FSaIIC fibrosarcoma and EMT6 mammary carcinoma.
Teicher BA; Herman TS; Tanaka J; Eder JP; Holden SA; Bubley G; Coleman CN; Frei E
Cancer Res; 1991 Feb; 51(4):1086-91. PubMed ID: 1825474
[TBL] [Abstract][Full Text] [Related]
4. Combination of N,N',N"-triethylenethiophosphoramide and cyclophosphamide in vitro and in vivo.
Teicher BA; Holden SA; Cucchi CA; Cathcart KN; Korbut TT; Flatow JL; Frei E
Cancer Res; 1988 Jan; 48(1):94-100. PubMed ID: 3121169
[TBL] [Abstract][Full Text] [Related]
5. Preclinical studies relating to the use of thiotepa in the high-dose setting alone and in combination.
Teicher BA; Holden SA; Eder JP; Herman TS; Antman KH; Frei E
Semin Oncol; 1990 Feb; 17(1 Suppl 3):18-32. PubMed ID: 2106164
[TBL] [Abstract][Full Text] [Related]
6. Lonidamine as a modulator of alkylating agent activity in vitro and in vivo.
Teicher BA; Herman TS; Holden SA; Epelbaum R; Liu SD; Frei E
Cancer Res; 1991 Feb; 51(3):780-4. PubMed ID: 1988117
[TBL] [Abstract][Full Text] [Related]
7. Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
Ng SF; Waxman DJ
Cancer Res; 1990 Feb; 50(3):464-71. PubMed ID: 2105156
[TBL] [Abstract][Full Text] [Related]
8. Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism.
Chang TK; Chen G; Waxman DJ
J Pharmacol Exp Ther; 1995 Jul; 274(1):270-5. PubMed ID: 7616408
[TBL] [Abstract][Full Text] [Related]
9. Effects of RSR13 and oxygen on the cytotoxicity of cisplatin and carboplatin to EMT6 mouse mammary tumor cells in vitro and in vivo.
Donnelly ET; Kelley M; Rockwell S
Cancer Chemother Pharmacol; 2004 Jan; 53(1):43-50. PubMed ID: 14574460
[TBL] [Abstract][Full Text] [Related]
10. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
11. Influence of schedule on alkylating agent cytotoxicity in vitro and in vivo.
Teicher BA; Holden SA; Eder JP; Brann TW; Jones SM; Frei E
Cancer Res; 1989 Nov; 49(21):5994-8. PubMed ID: 2790813
[TBL] [Abstract][Full Text] [Related]
12. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Quintieri L; Rosato A; Napoli E; Sola F; Geroni C; Floreani M; Zanovello P
Cancer Res; 2000 Jun; 60(12):3232-8. PubMed ID: 10866316
[TBL] [Abstract][Full Text] [Related]
13. Effects of various oxygenation conditions on the enhancement by Fluosol-DA of melphalan antitumor activity.
Teicher BA; Crawford JM; Holden SA; Cathcart KN
Cancer Res; 1987 Oct; 47(19):5036-41. PubMed ID: 3113727
[TBL] [Abstract][Full Text] [Related]
14. N,N',N''-triethylenethiophosphoramide (thio-TEPA) oxygenation by constitutive hepatic P450 enzymes and modulation of drug metabolism and clearance in vivo by P450-inducing agents.
Ng SF; Waxman DJ
Cancer Res; 1991 May; 51(9):2340-5. PubMed ID: 1707751
[TBL] [Abstract][Full Text] [Related]
15. Effect of oxygen on the cytotoxicity and antitumor activity of etoposide.
Teicher BA; Holden SA; Rose CM
J Natl Cancer Inst; 1985 Dec; 75(6):1129-33. PubMed ID: 3934448
[TBL] [Abstract][Full Text] [Related]
16. Efficacy of pentoxifylline as a modulator of alkylating agent activity in vitro and in vivo.
Teicher BA; Holden SA; Herman TS; Epelbaum R; Pardee AB; Dezube B
Anticancer Res; 1991; 11(4):1555-60. PubMed ID: 1746913
[TBL] [Abstract][Full Text] [Related]
17. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
Keyes SR; Fracasso PM; Heimbrook DC; Rockwell S; Sligar SG; Sartorelli AC
Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671
[TBL] [Abstract][Full Text] [Related]
18. Approaches to defining the mechanism of enhancement by Fluosol-DA 20% with carbogen of melphalan antitumor activity.
Teicher BA; Holden SA; Jacobs JL
Cancer Res; 1987 Jan; 47(2):513-8. PubMed ID: 3098413
[TBL] [Abstract][Full Text] [Related]
19. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
Pritsos CA; Sartorelli AC
Cancer Res; 1986 Jul; 46(7):3528-32. PubMed ID: 3011250
[TBL] [Abstract][Full Text] [Related]
20. Restoration of tumor oxygenation after cytotoxic therapy by a perflubron emulsion/carbogen breathing.
Teicher BA; Holden SA; Ara G; Dupuis NP; Goff D
Cancer J Sci Am; 1995; 1(1):43-8. PubMed ID: 9166453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]