These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 25051958)

  • 1. A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.
    Luo J; Sun L; Lin X; Liu G; Yu J; Parisiadou L; Xie C; Ding J; Cai H
    Hum Mol Genet; 2014 Dec; 23(24):6567-74. PubMed ID: 25051958
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.
    Lin X; Parisiadou L; Sgobio C; Liu G; Yu J; Sun L; Shim H; Gu XL; Luo J; Long CX; Ding J; Mateo Y; Sullivan PH; Wu LG; Goldstein DS; Lovinger D; Cai H
    J Neurosci; 2012 Jul; 32(27):9248-64. PubMed ID: 22764233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
    Pavia-Collado R; Cóppola-Segovia V; Miquel-Rio L; Alarcón-Aris D; Rodríguez-Aller R; Torres-López M; Paz V; Ruiz-Bronchal E; Campa L; Artigas F; Montefeltro A; Revilla R; Bortolozzi A
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805843
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease.
    Harischandra DS; Jin H; Anantharam V; Kanthasamy A; Kanthasamy AG
    Toxicol Sci; 2015 Feb; 143(2):454-68. PubMed ID: 25416158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The interaction between calcineurin and α-synuclein is regulated by calcium and calmodulin.
    Shi X; Sun Y; Wang P; Gu L; Wang L; Yang H; Wei Q; Li Z; Luo J
    Biochem Biophys Res Commun; 2018 Feb; 496(4):1109-1114. PubMed ID: 29409956
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
    Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
    J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology.
    Diao X; Wang F; Becerra-Calixto A; Soto C; Mukherjee A
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.
    Batelli S; Invernizzi RW; Negro A; Calcagno E; Rodilossi S; Forloni G; Albani D
    Neurodegener Dis; 2015; 15(1):13-23. PubMed ID: 25500798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
    Yang J; Luo S; Zhang J; Yu T; Fu Z; Zheng Y; Xu X; Liu C; Fan M; Zhang Z
    Neurobiol Dis; 2021 Jan; 148():105218. PubMed ID: 33296726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.
    Castro-Sánchez S; García-Yagüe ÁJ; López-Royo T; Casarejos M; Lanciego JL; Lastres-Becker I
    Glia; 2018 Aug; 66(8):1752-1762. PubMed ID: 29624735
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation.
    Li J; Ng KW; Sung CC; Chung KKK
    J Neurochem; 2024 Jul; 168(7):1215-1236. PubMed ID: 38693066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
    Sharma N; Rao SP; Kalivendi SV
    Free Radic Biol Med; 2019 May; 135():28-37. PubMed ID: 30796974
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA damage preceding dopamine neuron degeneration in A53T human α-synuclein transgenic mice.
    Wang D; Yu T; Liu Y; Yan J; Guo Y; Jing Y; Yang X; Song Y; Tian Y
    Biochem Biophys Res Commun; 2016 Dec; 481(1-2):104-110. PubMed ID: 27818201
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Age-dependent neurodegeneration and neuroinflammation in a genetic A30P/A53T double-mutated α-synuclein mouse model of Parkinson's disease.
    Rauschenberger L; Behnke J; Grotemeyer A; Knorr S; Volkmann J; Ip CW
    Neurobiol Dis; 2022 Sep; 171():105798. PubMed ID: 35750147
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tau knockout exacerbates degeneration of parvalbumin-positive neurons in substantia nigra pars reticulata in Parkinson's disease-related α-synuclein A53T mice.
    Jiao L; Zheng M; Duan J; Wu T; Li Z; Liu L; Xiang X; Tang X; He J; Li X; Zhang G; Ding J; Cai H; Lin X
    FASEB J; 2020 Sep; 34(9):12239-12254. PubMed ID: 33000527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Early Parkinson's disease symptoms in α-synuclein transgenic monkeys.
    Niu Y; Guo X; Chen Y; Wang CE; Gao J; Yang W; Kang Y; Si W; Wang H; Yang SH; Li S; Ji W; Li XJ
    Hum Mol Genet; 2015 Apr; 24(8):2308-17. PubMed ID: 25552648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice.
    Di Martino R; Sisalli MJ; Sirabella R; Della Notte S; Borzacchiello D; Feliciello A; Annunziato L; Scorziello A
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360942
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease.
    Tatenhorst L; Eckermann K; Dambeck V; Fonseca-Ornelas L; Walle H; Lopes da Fonseca T; Koch JC; Becker S; Tönges L; Bähr M; Outeiro TF; Zweckstetter M; Lingor P
    Acta Neuropathol Commun; 2016 Apr; 4():39. PubMed ID: 27101974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
    Zhu Q; Zhuang XX; Chen JY; Yuan NN; Chen Y; Cai CZ; Tan JQ; Su HX; Lu JH
    Phytomedicine; 2021 Jul; 87():153578. PubMed ID: 34038839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Calcineurin determines toxic versus beneficial responses to α-synuclein.
    Caraveo G; Auluck PK; Whitesell L; Chung CY; Baru V; Mosharov EV; Yan X; Ben-Johny M; Soste M; Picotti P; Kim H; Caldwell KA; Caldwell GA; Sulzer D; Yue DT; Lindquist S
    Proc Natl Acad Sci U S A; 2014 Aug; 111(34):E3544-52. PubMed ID: 25122673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.