These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 25056547)

  • 1. DNA break mapping reveals topoisomerase II activity genome-wide.
    Baranello L; Kouzine F; Wojtowicz D; Cui K; Przytycka TM; Zhao K; Levens D
    Int J Mol Sci; 2014 Jul; 15(7):13111-22. PubMed ID: 25056547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mapping DNA Breaks by Next-Generation Sequencing.
    Baranello L; Kouzine F; Wojtowicz D; Cui K; Zhao K; Przytycka TM; Capranico G; Levens D
    Methods Mol Biol; 2018; 1672():155-166. PubMed ID: 29043624
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome.
    Gittens WH; Johnson DJ; Allison RM; Cooper TJ; Thomas H; Neale MJ
    Nat Commun; 2019 Oct; 10(1):4846. PubMed ID: 31649282
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.
    Sciascia N; Wu W; Zong D; Sun Y; Wong N; John S; Wangsa D; Ried T; Bunting SF; Pommier Y; Nussenzweig A
    Elife; 2020 Feb; 9():. PubMed ID: 32057297
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution.
    Szlachta K; Raimer HM; Comeau LD; Wang YH
    BMC Genomics; 2020 Jan; 21(1):25. PubMed ID: 31914926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks.
    Kametani Y; Takahata C; Narita T; Tanaka K; Iwai S; Kuraoka I
    Carcinogenesis; 2016 Jan; 37(1):56-62. PubMed ID: 26581212
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
    Goodenow D; Emmanuel F; Berman C; Sahyouni M; Richardson C
    Mutat Res Genet Toxicol Environ Mutagen; 2020 Jan; 849():503144. PubMed ID: 32087851
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
    Canela A; Maman Y; Huang SN; Wutz G; Tang W; Zagnoli-Vieira G; Callen E; Wong N; Day A; Peters JM; Caldecott KW; Pommier Y; Nussenzweig A
    Mol Cell; 2019 Jul; 75(2):252-266.e8. PubMed ID: 31202577
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
    Morimoto S; Tsuda M; Bunch H; Sasanuma H; Austin C; Takeda S
    Genes (Basel); 2019 Oct; 10(11):. PubMed ID: 31671674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks.
    Singh S; Szlachta K; Manukyan A; Raimer HM; Dinda M; Bekiranov S; Wang YH
    J Biol Chem; 2020 Mar; 295(12):3990-4000. PubMed ID: 32029477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
    Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
    PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot.
    Mirault ME; Boucher P; Tremblay A
    Am J Hum Genet; 2006 Nov; 79(5):779-91. PubMed ID: 17033956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposide.
    Tammaro M; Barr P; Ricci B; Yan H
    PLoS One; 2013; 8(11):e79202. PubMed ID: 24244448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
    Gómez-Herreros F; Zagnoli-Vieira G; Ntai I; Martínez-Macías MI; Anderson RM; Herrero-Ruíz A; Caldecott KW
    Nat Commun; 2017 Aug; 8(1):233. PubMed ID: 28794467
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway.
    Park JM; Zhang H; Nie L; Wang C; Huang M; Feng X; Tang M; Chen Z; Xiong Y; Lee N; Li S; Yin L; Hart T; Chen J
    Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047518
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
    Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
    Sasanuma H; Tsuda M; Morimoto S; Saha LK; Rahman MM; Kiyooka Y; Fujiike H; Cherniack AD; Itou J; Callen Moreu E; Toi M; Nakada S; Tanaka H; Tsutsui K; Yamada S; Nussenzweig A; Takeda S
    Proc Natl Acad Sci U S A; 2018 Nov; 115(45):E10642-E10651. PubMed ID: 30352856
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploring the SSBreakome: genome-wide mapping of DNA single-strand breaks by next-generation sequencing.
    Zilio N; Ulrich HD
    FEBS J; 2021 Jul; 288(13):3948-3961. PubMed ID: 32965079
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks.
    Szlachta K; Manukyan A; Raimer HM; Singh S; Salamon A; Guo W; Lobachev KS; Wang YH
    Nucleic Acids Res; 2020 Jul; 48(12):6654-6671. PubMed ID: 32501506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
    Tammaro M; Liao S; Beeharry N; Yan H
    Nucleic Acids Res; 2016 Jan; 44(1):221-31. PubMed ID: 26420828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.