BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 25058922)

  • 1. CKD712, a synthetic isoquinoline alkaloid, enhances the anti-cancer effects of paclitaxel in MDA-MB-231 cells through regulation of PTEN.
    Kim YM; Tsoyi K; Jang HJ; Park EJ; Park SW; Kim HJ; Hwa JS; Chang KC
    Life Sci; 2014 Sep; 112(1-2):49-58. PubMed ID: 25058922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells.
    Tsoyi K; Kim WS; Kim YM; Kim HJ; Seo HG; Lee JH; Yun-Choi HS; Chang KC
    Atherosclerosis; 2009 Dec; 207(2):412-9. PubMed ID: 19540498
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide.
    Patel NM; Nozaki S; Shortle NH; Bhat-Nakshatri P; Newton TR; Rice S; Gelfanov V; Boswell SH; Goulet RJ; Sledge GW; Nakshatri H
    Oncogene; 2000 Aug; 19(36):4159-69. PubMed ID: 10962577
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ginsenoside Rg3 promotes cytotoxicity of Paclitaxel through inhibiting NF-κB signaling and regulating Bax/Bcl-2 expression on triple-negative breast cancer.
    Yuan Z; Jiang H; Zhu X; Liu X; Li J
    Biomed Pharmacother; 2017 May; 89():227-232. PubMed ID: 28231544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride.
    Tsoyi K; Kim HJ; Shin JS; Kim DH; Cho HJ; Lee SS; Ahn SK; Yun-Choi HS; Lee JH; Seo HG; Chang KC
    Cell Signal; 2008 Oct; 20(10):1839-47. PubMed ID: 18634870
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Simvastatin in combination with bergamottin potentiates TNF-induced apoptosis through modulation of NF-κB signalling pathway in human chronic myelogenous leukaemia.
    Kim SM; Lee EJ; Lee JH; Yang WM; Nam D; Lee JH; Lee SG; Um JY; Shim BS; Ahn KS
    Pharm Biol; 2016 Oct; 54(10):2050-60. PubMed ID: 26911804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.
    Aggarwal BB; Shishodia S; Takada Y; Banerjee S; Newman RA; Bueso-Ramos CE; Price JE
    Clin Cancer Res; 2005 Oct; 11(20):7490-8. PubMed ID: 16243823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Indole-3-carbinol-induced modulation of NF-kappaB signalling is breast cancer cell-specific and does not correlate with cell death.
    Moiseeva EP; Heukers R
    Breast Cancer Res Treat; 2008 Jun; 109(3):451-62. PubMed ID: 17653853
    [TBL] [Abstract][Full Text] [Related]  

  • 9. (S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) reduces rat myocardial apoptosis against ischemia and reperfusion injury by activation of phosphatidylinositol 3-kinase/Akt signaling and anti-inflammatory action in vivo.
    Jin YC; Lee YS; Kim YM; Seo HG; Lee JH; Kim HJ; Yun-Choi HS; Chang KC
    J Pharmacol Exp Ther; 2009 Aug; 330(2):440-8. PubMed ID: 19458286
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth.
    Ghosh-Choudhury T; Mandal CC; Woodruff K; St Clair P; Fernandes G; Choudhury GG; Ghosh-Choudhury N
    Breast Cancer Res Treat; 2009 Nov; 118(1):213-28. PubMed ID: 18953692
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products.
    Yodkeeree S; Pompimon W; Limtrakul P
    Tumour Biol; 2014 Sep; 35(9):8615-24. PubMed ID: 24867094
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK; Sung B; Kunnumakkara AB; Sethi G; Chaturvedi MM; Aggarwal BB
    Cancer Res; 2008 Jul; 68(13):5370-9. PubMed ID: 18593939
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ganoderic acids suppress growth and angiogenesis by modulating the NF-κB signaling pathway in breast cancer cells.
    Li F; Wang Y; Wang X; Li J; Cui H; Niu M
    Int J Clin Pharmacol Ther; 2012 Oct; 50(10):712-21. PubMed ID: 22762853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA; Vellon L; Colomer R; Lupu R
    Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis.
    Dong QG; Sclabas GM; Fujioka S; Schmidt C; Peng B; Wu T; Tsao MS; Evans DB; Abbruzzese JL; McDonnell TJ; Chiao PJ
    Oncogene; 2002 Sep; 21(42):6510-9. PubMed ID: 12226754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TNF-alpha upregulates PTEN via NF-kappaB signaling pathways in human leukemic cells.
    Lee YR; Yu HN; Noh EM; Youn HJ; Song EK; Han MK; Park CS; Kim BS; Park YS; Park BK; Lee SH; Kim JS
    Exp Mol Med; 2007 Feb; 39(1):121-7. PubMed ID: 17334236
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model.
    Kang HJ; Lee SH; Price JE; Kim LS
    Breast J; 2009; 15(3):223-9. PubMed ID: 19645775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.
    Ma J; Sawai H; Matsuo Y; Ochi N; Yasuda A; Takahashi H; Wakasugi T; Funahashi H; Sato M; Takeyama H
    J Surg Res; 2010 May; 160(1):90-101. PubMed ID: 19560785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.