167 related articles for article (PubMed ID: 25063032)
1. Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy.
Ling Y; Zhang X; Bai Y; Li P; Wei C; Song T; Zheng Z; Guan K; Zhang Y; Zhang B; Liu X; Ma RZ; Cao C; Zhong H; Xu Q
Biochem Biophys Res Commun; 2014 Aug; 450(4):1690-5. PubMed ID: 25063032
[TBL] [Abstract][Full Text] [Related]
2. Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses.
Zhang X; Yin Q; Ling Y; Zhang Y; Ma R; Ma Q; Cao C; Zhong H; Liu X; Xu Q
Cell Cycle; 2011 Aug; 10(16):2742-50. PubMed ID: 21778823
[TBL] [Abstract][Full Text] [Related]
3. Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex.
Tipton AR; Ji W; Sturt-Gillespie B; Bekier ME; Wang K; Taylor WR; Liu ST
J Biol Chem; 2013 Dec; 288(49):35149-58. PubMed ID: 24151075
[TBL] [Abstract][Full Text] [Related]
4. Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility.
Martinez R; Blasina A; Hallin JF; Hu W; Rymer I; Fan J; Hoffman RL; Murphy S; Marx M; Yanochko G; Trajkovic D; Dinh D; Timofeevski S; Zhu Z; Sun P; Lappin PB; Murray BW
PLoS One; 2015; 10(9):e0138616. PubMed ID: 26398286
[TBL] [Abstract][Full Text] [Related]
5. Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells.
von Schubert C; Cubizolles F; Bracher JM; Sliedrecht T; Kops GJPL; Nigg EA
Cell Rep; 2015 Jul; 12(1):66-78. PubMed ID: 26119734
[TBL] [Abstract][Full Text] [Related]
6. Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint.
Kang J; Chen Y; Zhao Y; Yu H
Proc Natl Acad Sci U S A; 2007 Dec; 104(51):20232-7. PubMed ID: 18083840
[TBL] [Abstract][Full Text] [Related]
7. Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
Jemaà M; Manic G; Lledo G; Lissa D; Reynes C; Morin N; Chibon F; Sistigu A; Castedo M; Vitale I; Kroemer G; Abrieu A
Oncotarget; 2016 Jan; 7(1):885-901. PubMed ID: 26637805
[TBL] [Abstract][Full Text] [Related]
8. Mps1 kinase regulates tumor cell viability via its novel role in mitochondria.
Zhang X; Ling Y; Guo Y; Bai Y; Shi X; Gong F; Tan P; Zhang Y; Wei C; He X; Ramirez A; Liu X; Cao C; Zhong H; Xu Q; Ma RZ
Cell Death Dis; 2016 Jul; 7(7):e2292. PubMed ID: 27383047
[TBL] [Abstract][Full Text] [Related]
9. PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression.
Teye EK; Lu S; Chen F; Yang W; Abraham T; Stairs DB; Wang HG; Yochum GS; Brodsky RA; Pu JJ
Sci Rep; 2021 Sep; 11(1):19022. PubMed ID: 34561473
[TBL] [Abstract][Full Text] [Related]
10. Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment.
Yang H; Zhang F; Huang CJ; Liao J; Han Y; Hao P; Chu Y; Lu X; Li W; Yu H; Kang J
Mol Biol Cell; 2019 Apr; 30(9):1060-1068. PubMed ID: 30785839
[TBL] [Abstract][Full Text] [Related]
11. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer.
Mason JM; Wei X; Fletcher GC; Kiarash R; Brokx R; Hodgson R; Beletskaya I; Bray MR; Mak TW
Proc Natl Acad Sci U S A; 2017 Mar; 114(12):3127-3132. PubMed ID: 28270606
[TBL] [Abstract][Full Text] [Related]
12. A Biosensor for the Mitotic Kinase MPS1 Reveals Spatiotemporal Activity Dynamics and Regulation.
Kuijt TEF; Lambers MLA; Weterings S; Ponsioen B; Bolhaqueiro ACF; Staijen DHM; Kops GJPL
Curr Biol; 2020 Oct; 30(19):3862-3870.e6. PubMed ID: 32888483
[TBL] [Abstract][Full Text] [Related]
13. Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy.
Faisal A; Mak GWY; Gurden MD; Xavier CPR; Anderhub SJ; Innocenti P; Westwood IM; Naud S; Hayes A; Box G; Valenti MR; De Haven Brandon AK; O'Fee L; Schmitt J; Woodward HL; Burke R; vanMontfort RLM; Blagg J; Raynaud FI; Eccles SA; Hoelder S; Linardopoulos S
Br J Cancer; 2017 Apr; 116(9):1166-1176. PubMed ID: 28334731
[TBL] [Abstract][Full Text] [Related]
14. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.
Daniel J; Coulter J; Woo JH; Wilsbach K; Gabrielson E
Proc Natl Acad Sci U S A; 2011 Mar; 108(13):5384-9. PubMed ID: 21402910
[TBL] [Abstract][Full Text] [Related]
15. High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers.
Anderhub SJ; Mak GW; Gurden MD; Faisal A; Drosopoulos K; Walsh K; Woodward HL; Innocenti P; Westwood IM; Naud S; Hayes A; Theofani E; Filosto S; Saville H; Burke R; van Montfort RLM; Raynaud FI; Blagg J; Hoelder S; Eccles SA; Linardopoulos S
Mol Cancer Ther; 2019 Oct; 18(10):1696-1707. PubMed ID: 31575759
[TBL] [Abstract][Full Text] [Related]
16. Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation.
Xu Q; Zhu S; Wang W; Zhang X; Old W; Ahn N; Liu X
Mol Biol Cell; 2009 Jan; 20(1):10-20. PubMed ID: 18923149
[TBL] [Abstract][Full Text] [Related]
17. Monopolar spindle 1 (MPS1) protein-dependent phosphorylation of RecQ-mediated genome instability protein 2 (RMI2) at serine 112 is essential for BLM-Topo III α-RMI1-RMI2 (BTR) protein complex function upon spindle assembly checkpoint (SAC) activation during mitosis.
Pradhan A; Singh TR; Ali AM; Wahengbam K; Meetei AR
J Biol Chem; 2013 Nov; 288(47):33500-33508. PubMed ID: 24108125
[TBL] [Abstract][Full Text] [Related]
18. Ablation of the spindle assembly checkpoint by a compound targeting Mps1.
Schmidt M; Budirahardja Y; Klompmaker R; Medema RH
EMBO Rep; 2005 Sep; 6(9):866-72. PubMed ID: 16113653
[TBL] [Abstract][Full Text] [Related]
19. Modulation of miR-21 signaling by MPS1 in human glioblastoma.
Maachani UB; Tandle A; Shankavaram U; Kramp T; Camphausen K
Oncotarget; 2016 Aug; 7(33):52912-52927. PubMed ID: 25991676
[TBL] [Abstract][Full Text] [Related]
20. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine.
Santaguida S; Tighe A; D'Alise AM; Taylor SS; Musacchio A
J Cell Biol; 2010 Jul; 190(1):73-87. PubMed ID: 20624901
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
