These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 25063512)

  • 1. Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
    Lin F; Qin ZH
    J Huntingtons Dis; 2013; 2(2):149-57. PubMed ID: 25063512
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Huntington's disease: degradation of mutant huntingtin by autophagy.
    Sarkar S; Rubinsztein DC
    FEBS J; 2008 Sep; 275(17):4263-70. PubMed ID: 18637946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein.
    Qi L; Zhang XD
    Acta Biochim Biophys Sin (Shanghai); 2014 Feb; 46(2):83-91. PubMed ID: 24323530
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W; Chaurette J; Pfister EL; Kennington LA; Chase KO; Bullock J; Vonsattel JP; Faull RL; Macdonald D; DiFiglia M; Zamore PD; Aronin N
    J Huntingtons Dis; 2013; 2(4):491-500. PubMed ID: 25062733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clearance of mutant proteins as a therapeutic target in neurodegenerative diseases.
    Krainc D
    Arch Neurol; 2010 Apr; 67(4):388-92. PubMed ID: 20385902
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
    Ciechanover A; Kwon YT
    Exp Mol Med; 2015 Mar; 47(3):e147. PubMed ID: 25766616
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy.
    Cortes CJ; La Spada AR
    Drug Discov Today; 2014 Jul; 19(7):963-71. PubMed ID: 24632005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.
    Wold MS; Lim J; Lachance V; Deng Z; Yue Z
    Mol Neurodegener; 2016 Dec; 11(1):76. PubMed ID: 27938392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagy in Huntington disease and huntingtin in autophagy.
    Martin DD; Ladha S; Ehrnhoefer DE; Hayden MR
    Trends Neurosci; 2015 Jan; 38(1):26-35. PubMed ID: 25282404
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.
    Wong VK; Wu AG; Wang JR; Liu L; Law BY
    Molecules; 2015 Feb; 20(3):3496-514. PubMed ID: 25699594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
    Rose C; Menzies FM; Renna M; Acevedo-Arozena A; Corrochano S; Sadiq O; Brown SD; Rubinsztein DC
    Hum Mol Genet; 2010 Jun; 19(11):2144-53. PubMed ID: 20190273
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autophagy regulates the processing of amino terminal huntingtin fragments.
    Qin ZH; Wang Y; Kegel KB; Kazantsev A; Apostol BL; Thompson LM; Yoder J; Aronin N; DiFiglia M
    Hum Mol Genet; 2003 Dec; 12(24):3231-44. PubMed ID: 14570716
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease.
    Skogen M; Roth J; Yerkes S; Parekh-Olmedo H; Kmiec E
    BMC Neurosci; 2006 Oct; 7():65. PubMed ID: 17014717
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.
    Bauer PO; Goswami A; Wong HK; Okuno M; Kurosawa M; Yamada M; Miyazaki H; Matsumoto G; Kino Y; Nagai Y; Nukina N
    Nat Biotechnol; 2010 Mar; 28(3):256-63. PubMed ID: 20190739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of post-translational modifications of huntingtin in the pathogenesis of Huntington's disease.
    Wang Y; Lin F; Qin ZH
    Neurosci Bull; 2010 Apr; 26(2):153-62. PubMed ID: 20332821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Huntingtin and its role in neuronal degeneration.
    Li SH; Li XJ
    Neuroscientist; 2004 Oct; 10(5):467-75. PubMed ID: 15359012
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.
    Williams A; Jahreiss L; Sarkar S; Saiki S; Menzies FM; Ravikumar B; Rubinsztein DC
    Curr Top Dev Biol; 2006; 76():89-101. PubMed ID: 17118264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.
    Daldin M; Fodale V; Cariulo C; Azzollini L; Verani M; Martufi P; Spiezia MC; Deguire SM; Cherubini M; Macdonald D; Weiss A; Bresciani A; Vonsattel JG; Petricca L; Marsh JL; Gines S; Santimone I; Marano M; Lashuel HA; Squitieri F; Caricasole A
    Sci Rep; 2017 Jul; 7(1):5070. PubMed ID: 28698602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein.
    Omi K; Hachiya NS; Tanaka M; Tokunaga K; Kaneko K
    Neurosci Lett; 2008 Jan; 431(1):45-50. PubMed ID: 18078716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.
    Matthes F; Massari S; Bochicchio A; Schorpp K; Schilling J; Weber S; Offermann N; Desantis J; Wanker E; Carloni P; Hadian K; Tabarrini O; Rossetti G; Krauss S
    ACS Chem Neurosci; 2018 Jun; 9(6):1399-1408. PubMed ID: 29506378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.