BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 25063530)

  • 1. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease.
    Wang X; Wang H; Yang H; Li J; Cai Q; Shapiro IM; Risbud MV
    Am J Pathol; 2014 Sep; 184(9):2560-72. PubMed ID: 25063530
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TNF-α and TGF-β1 regulate Syndecan-4 expression in nucleus pulposus cells: role of the mitogen-activated protein kinase and NF-κB pathways.
    Yang H; Liu H; Li X; Pan H; Li Z; Wang J; Zheng Z
    Connect Tissue Res; 2015; 56(4):281-7. PubMed ID: 25491150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.
    Wang H; Tian Y; Wang J; Phillips KLE; Binch ALA; Dunn S; Cross A; Chiverton N; Zheng Z; Shapiro IM; Le Maitre CL; Risbud MV
    J Biol Chem; 2013 Jun; 288(23):16761-16774. PubMed ID: 23589286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.
    Wang J; Tian Y; Phillips KL; Chiverton N; Haddock G; Bunning RA; Cross AK; Shapiro IM; Le Maitre CL; Risbud MV
    Arthritis Rheum; 2013 Mar; 65(3):832-42. PubMed ID: 23233369
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
    Tian Y; Yuan W; Fujita N; Wang J; Wang H; Shapiro IM; Risbud MV
    Am J Pathol; 2013 Jun; 182(6):2310-21. PubMed ID: 23602832
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration.
    Studer RK; Aboka AM; Gilbertson LG; Georgescu H; Sowa G; Vo N; Kang JD
    Spine (Phila Pa 1976); 2007 Dec; 32(25):2827-33. PubMed ID: 18246004
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.
    Fujita N; Gogate SS; Chiba K; Toyama Y; Shapiro IM; Risbud MV
    J Biol Chem; 2012 Nov; 287(47):39942-53. PubMed ID: 22948157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ginsenoside Rg1 relieves rat intervertebral disc degeneration and inhibits IL-1β-induced nucleus pulposus cell apoptosis and inflammation via NF-κB signaling pathway.
    Yu L; Hao YJ; Ren ZN; Zhu GD; Zhou WW; Lian X; Wu XJ
    In Vitro Cell Dev Biol Anim; 2024 Mar; 60(3):287-299. PubMed ID: 38485818
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
    Li J; Yuan W; Jiang S; Ye W; Yang H; Shapiro IM; Risbud MV
    J Biol Chem; 2015 Mar; 290(11):7195-207. PubMed ID: 25635047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Follistatin-like protein 1 promotes inflammatory reactions in nucleus pulposus cells by interacting with the MAPK and NFκB signaling pathways.
    Liu Y; Wei J; Zhao Y; Zhang Y; Han Y; Chen B; Cheng K; Jia J; Nie L; Cheng L
    Oncotarget; 2017 Jun; 8(26):43023-43034. PubMed ID: 28498809
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Paracrine Effect of Degenerated Disc Cells on Healthy Human Nucleus Pulposus Cells Is Mediated by MAPK and NF-κB Pathways and Can Be Reduced by TGF-β1.
    Cai F; Zhu L; Wang F; Shi R; Xie XH; Hong X; Wang XH; Wu XT
    DNA Cell Biol; 2017 Feb; 36(2):143-158. PubMed ID: 28005398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration.
    Tran CM; Schoepflin ZR; Markova DZ; Kepler CK; Anderson DG; Shapiro IM; Risbud MV
    J Biol Chem; 2014 Mar; 289(11):7374-87. PubMed ID: 24464580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of nuclear factor kappa B signaling pathway in human intervertebral disc degeneration.
    Zhongyi S; Sai Z; Chao L; Jiwei T
    Spine (Phila Pa 1976); 2015 Feb; 40(4):224-32. PubMed ID: 25494317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRD4 inhibition regulates MAPK, NF-κB signals, and autophagy to suppress MMP-13 expression in diabetic intervertebral disc degeneration.
    Wang J; Hu J; Chen X; Huang C; Lin J; Shao Z; Gu M; Wu Y; Tian N; Gao W; Zhou Y; Wang X; Zhang X
    FASEB J; 2019 Oct; 33(10):11555-11566. PubMed ID: 31331201
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin-1β exacerbates the catabolic effects of human nucleus pulposus cells through activation of the Nuclear Factor kappa B signaling pathway under hypoxic conditions.
    Sun ZY; Liu YT; Liang H; Li Y; Wang DG; Tian JW
    Eur Rev Med Pharmacol Sci; 2018 Nov; 22(21):7129-7139. PubMed ID: 30468453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Collagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.
    Feng C; He J; Zhang Y; Lan M; Yang M; Liu H; Huang B; Pan Y; Zhou Y
    Int J Mol Med; 2017 Jul; 40(1):164-174. PubMed ID: 28560408
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Expression of NF-κB in a degenerative human intervertebral disc model].
    Wang XF; Zhang AP; Sun ZY; Liu C; Kuang LH; Tian JW
    Zhonghua Yi Xue Za Zhi; 2017 May; 97(17):1324-1329. PubMed ID: 28482435
    [No Abstract]   [Full Text] [Related]  

  • 18. Alarmins S100A8/A9 promote intervertebral disc degeneration and inflammation-related pain in a rat model through toll-like receptor-4 and activation of the NF-κB signaling pathway.
    Zheng J; Wang J; Liu H; Chen F; Wang H; Chen S; Xie J; Zheng Z; Li Z
    Osteoarthritis Cartilage; 2022 Jul; 30(7):998-1011. PubMed ID: 35405347
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.
    Wang J; Markova D; Anderson DG; Zheng Z; Shapiro IM; Risbud MV
    J Biol Chem; 2011 Nov; 286(46):39738-49. PubMed ID: 21949132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Naringin Protects Against Interleukin 1β (IL-1β)-Induced Human Nucleus Pulposus Cells Degeneration via Downregulation Nuclear Factor kappa B (NF-κB) Pathway and p53 Expression.
    Gao G; Chang F; Zhang T; Huang X; Yu C; Hu Z; Ji M; Duan Y
    Med Sci Monit; 2019 Dec; 25():9963-9972. PubMed ID: 31927560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.