BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

453 related articles for article (PubMed ID: 25063944)

  • 1. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
    Squarcialupi L; Colotta V; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Borea PA; Porta N; Ciancetta A; Moro S
    Eur J Med Chem; 2014 Sep; 84():614-27. PubMed ID: 25063944
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A
    Squarcialupi L; Betti M; Catarzi D; Varano F; Falsini M; Ravani A; Pasquini S; Vincenzi F; Salmaso V; Sturlese M; Varani K; Moro S; Colotta V
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):248-263. PubMed ID: 28114825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-Aminopyrimidines as dual adenosine A1/A2A antagonists.
    Robinson SJ; Petzer JP; Terre'Blanche G; Petzer A; van der Walt MM; Bergh JJ; Lourens AC
    Eur J Med Chem; 2015 Nov; 104():177-88. PubMed ID: 26462195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor.
    Squarcialupi L; Catarzi D; Varano F; Betti M; Falsini M; Vincenzi F; Ravani A; Ciancetta A; Varani K; Moro S; Colotta V
    Eur J Med Chem; 2016 Jan; 108():117-133. PubMed ID: 26638043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors.
    Squarcialupi L; Falsini M; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Dal Ben D; Lambertucci C; Volpini R; Colotta V
    Bioorg Med Chem; 2016 Jun; 24(12):2794-808. PubMed ID: 27161878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition.
    Lenzi O; Colotta V; Catarzi D; Varano F; Poli D; Filacchioni G; Varani K; Vincenzi F; Borea PA; Paoletta S; Morizzo E; Moro S
    J Med Chem; 2009 Dec; 52(23):7640-52. PubMed ID: 19743865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.
    Giovannoni MP; Vergelli C; Cilibrizzi A; Crocetti L; Biancalani C; Graziano A; Dal Piaz V; Loza MI; Cadavid MI; Díaz JL; Gavaldà A
    Bioorg Med Chem; 2010 Nov; 18(22):7890-9. PubMed ID: 20937560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-Substituted 2-benzylidene-1-tetralone analogues as A
    Janse van Rensburg HD; Terre'Blanche G; van der Walt MM; Legoabe LJ
    Bioorg Chem; 2017 Oct; 74():251-259. PubMed ID: 28881253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition.
    Cheong SL; Dolzhenko A; Kachler S; Paoletta S; Federico S; Cacciari B; Dolzhenko A; Klotz KN; Moro S; Spalluto G; Pastorin G
    J Med Chem; 2010 Apr; 53(8):3361-75. PubMed ID: 20307065
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A
    Varano F; Catarzi D; Falsini M; Vincenzi F; Pasquini S; Varani K; Colotta V
    Bioorg Med Chem; 2018 Jul; 26(12):3688-3695. PubMed ID: 29880250
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
    Pastorin G; Da Ros T; Spalluto G; Deflorian F; Moro S; Cacciari B; Baraldi PG; Gessi S; Varani K; Borea PA
    J Med Chem; 2003 Sep; 46(20):4287-96. PubMed ID: 13678407
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
    Baraldi PG; Fruttarolo F; Tabrizi MA; Preti D; Romagnoli R; El-Kashef H; Moorman A; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2003 Mar; 46(7):1229-41. PubMed ID: 12646033
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C2-substituted quinazolinone derivatives exhibit A
    Pieterse L; van der Walt MM; Terre'Blanche G
    Bioorg Med Chem Lett; 2020 Aug; 30(16):127274. PubMed ID: 32631506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.
    Baraldi PG; Saponaro G; Aghazadeh Tabrizi M; Baraldi S; Romagnoli R; Moorman AR; Varani K; Borea PA; Preti D
    Bioorg Med Chem; 2012 Jan; 20(2):1046-59. PubMed ID: 22204739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A
    Janse van Rensburg HD; Legoabe LJ; Terre'Blanche G; Aucamp J
    Bioorg Chem; 2020 Jan; 94():103459. PubMed ID: 31818481
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: potent and selective A(2A) adenosine antagonists.
    Baraldi PG; Cacciari B; Spalluto G; Pineda de las Infantas y Villatoro MJ; Zocchi C; Dionisotti S; Ongini E
    J Med Chem; 1996 Mar; 39(5):1164-71. PubMed ID: 8676354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A
    Harmse R; van der Walt MM; Petzer JP; Terre'Blanche G
    Bioorg Med Chem Lett; 2016 Dec; 26(24):5951-5955. PubMed ID: 27836398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A
    Alachouzos G; Lenselink EB; Mulder-Krieger T; de Vries H; IJzerman AP; Louvel J
    Eur J Med Chem; 2017 Jan; 125():586-602. PubMed ID: 27718474
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists.
    Poulsen SA; Quinn RJ
    J Med Chem; 1996 Oct; 39(21):4156-61. PubMed ID: 8863792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives.
    Matos MJ; Gaspar A; Kachler S; Klotz KN; Borges F; Santana L; Uriarte E
    J Pharm Pharmacol; 2013 Jan; 65(1):30-4. PubMed ID: 23215685
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.