These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 25064697)

  • 1. Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools.
    Hens B; Brouwers J; Anneveld B; Corsetti M; Symillides M; Vertzoni M; Reppas C; Turner DB; Augustijns P
    Eur J Pharm Sci; 2014 Oct; 63():233-42. PubMed ID: 25064697
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach.
    Paixão P; Bermejo M; Hens B; Tsume Y; Dickens J; Shedden K; Salehi N; Koenigsknecht MJ; Baker JR; Hasler WL; Lionberger R; Fan J; Wysocki J; Wen B; Lee A; Frances A; Amidon GE; Yu A; Benninghoff G; Löbenberg R; Talattof A; Sun D; Amidon GL
    Eur J Pharm Biopharm; 2018 Aug; 129():162-174. PubMed ID: 29857136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir.
    Shono Y; Jantratid E; Dressman JB
    Eur J Pharm Biopharm; 2011 Oct; 79(2):349-56. PubMed ID: 21527341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gastrointestinal dissolution, supersaturation and precipitation of the weak base indinavir in healthy volunteers.
    Rubbens J; Brouwers J; Tack J; Augustijns P
    Eur J Pharm Biopharm; 2016 Dec; 109():122-129. PubMed ID: 27693678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of surfactants, gastric emptying, and dosage form on supersaturation of dipyridamole in an in vitro model simulating the stomach and duodenum.
    Mitra A; Fadda HM
    Mol Pharm; 2014 Aug; 11(8):2835-44. PubMed ID: 25025699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.
    Koenigsknecht MJ; Baker JR; Wen B; Frances A; Zhang H; Yu A; Zhao T; Tsume Y; Pai MP; Bleske BE; Zhang X; Lionberger R; Lee A; Amidon GL; Hasler WL; Sun D
    Mol Pharm; 2017 Dec; 14(12):4295-4304. PubMed ID: 28937221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gastrointestinal and Systemic Disposition of Diclofenac under Fasted and Fed State Conditions Supporting the Evaluation of in Vitro Predictive Tools.
    Van Den Abeele J; Schilderink R; Schneider F; Mols R; Minekus M; Weitschies W; Brouwers J; Tack J; Augustijns P
    Mol Pharm; 2017 Dec; 14(12):4220-4232. PubMed ID: 28621952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Understanding the in vivo performance of enteric coated tablets using an in vitro-in silico-in vivo approach: case example diclofenac.
    Kambayashi A; Blume H; Dressman J
    Eur J Pharm Biopharm; 2013 Nov; 85(3 Pt B):1337-47. PubMed ID: 24056057
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.
    Hens B; Pathak SM; Mitra A; Patel N; Liu B; Patel S; Jamei M; Brouwers J; Augustijns P; Turner DB
    Mol Pharm; 2017 Dec; 14(12):4321-4333. PubMed ID: 28817288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states.
    Litou C; Patel N; Turner DB; Kostewicz E; Kuentz M; Box KJ; Dressman J
    Eur J Pharm Sci; 2019 Oct; 138():105031. PubMed ID: 31386891
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gastric and Duodenal Ethanol Concentrations after Intake of Alcoholic Beverages in Postprandial Conditions.
    Rubbens J; Riethorst D; Brouwers J; Wolfs K; Adams E; Tack J; Augustijns P
    Mol Pharm; 2017 Dec; 14(12):4202-4208. PubMed ID: 28731350
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of oral absorption of cinnarizine--a highly supersaturating poorly soluble weak base with borderline permeability.
    Berlin M; Przyklenk KH; Richtberg A; Baumann W; Dressman JB
    Eur J Pharm Biopharm; 2014 Nov; 88(3):795-806. PubMed ID: 25195981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Low dose caffeine as a salivary tracer for the determination of gastric water emptying in fed and fasted state: A MRI validation study.
    Sager M; Jedamzik P; Merdivan S; Grimm M; Schneider F; Kromrey ML; Hasan M; Oswald S; Kühn J; Koziolek M; Weitschies W
    Eur J Pharm Biopharm; 2018 Jun; 127():443-452. PubMed ID: 29602018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ethanol concentrations in the human gastrointestinal tract after intake of alcoholic beverages.
    Rubbens J; Brouwers J; Wolfs K; Adams E; Tack J; Augustijns P
    Eur J Pharm Sci; 2016 Apr; 86():91-5. PubMed ID: 26898927
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans.
    Shono Y; Jantratid E; Kesisoglou F; Reppas C; Dressman JB
    Eur J Pharm Biopharm; 2010 Sep; 76(1):95-104. PubMed ID: 20576487
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.
    Sjögren E; Westergren J; Grant I; Hanisch G; Lindfors L; Lennernäs H; Abrahamsson B; Tannergren C
    Eur J Pharm Sci; 2013 Jul; 49(4):679-98. PubMed ID: 23727464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gastric and Duodenal Diclofenac Concentrations in Healthy Volunteers after Intake of the FDA Standard Meal: In Vivo Observations and in Vitro Explorations.
    Rubbens J; Brouwers J; Tack J; Augustijns P
    Mol Pharm; 2019 Feb; 16(2):573-582. PubMed ID: 30571131
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An in vitro biorelevant gastrointestinal transfer (BioGIT) system for forecasting concentrations in the fasted upper small intestine: Design, implementation, and evaluation.
    Kourentas A; Vertzoni M; Stavrinoudakis N; Symillidis A; Brouwers J; Augustijns P; Reppas C; Symillides M
    Eur J Pharm Sci; 2016 Jan; 82():106-14. PubMed ID: 26594026
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model.
    Hens B; Talattof A; Paixão P; Bermejo M; Tsume Y; Löbenberg R; Amidon GL
    AAPS J; 2018 Mar; 20(3):57. PubMed ID: 29600330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drug dissolution and transit in a heterogenous gastric chyme after fed administration: Semi-mechanistic modeling and simulations for an immediate-release and orodispersible tablets containing a poorly soluble drug.
    Danielak D; Gajda M; Bołtromiuk T; Sulikowska K; Kubiak B; Romański M
    Eur J Pharm Biopharm; 2024 Jul; 200():114341. PubMed ID: 38795785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.