BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 25065682)

  • 1. Retinal and nonocular abnormalities in Cyp27a1(-/-)Cyp46a1(-/-) mice with dysfunctional metabolism of cholesterol.
    Saadane A; Mast N; Charvet CD; Omarova S; Zheng W; Huang SS; Kern TS; Peachey NS; Pikuleva IA
    Am J Pathol; 2014 Sep; 184(9):2403-19. PubMed ID: 25065682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina.
    Petrov AM; Astafev AA; Mast N; Saadane A; El-Darzi N; Pikuleva IA
    Biomolecules; 2019 Dec; 9(12):. PubMed ID: 31842366
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis.
    Omarova S; Charvet CD; Reem RE; Mast N; Zheng W; Huang S; Peachey NS; Pikuleva IA
    J Clin Invest; 2012 Aug; 122(8):3012-23. PubMed ID: 22820291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
    Mast N; Anderson KW; Lin JB; Li Y; Turko IV; Tatsuoka C; Bjorkhem I; Pikuleva IA
    J Biol Chem; 2017 Mar; 292(12):4913-4924. PubMed ID: 28190002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1-Mediated Cholesterol Removal.
    Saadane A; Mast N; Trichonas G; Chakraborty D; Hammer S; Busik JV; Grant MB; Pikuleva IA
    Am J Pathol; 2019 Feb; 189(2):405-425. PubMed ID: 30448403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells.
    Saadane A; Mast N; Dao T; Ahmad B; Pikuleva IA
    J Biol Chem; 2016 Sep; 291(39):20427-39. PubMed ID: 27514747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Hydroxypropyl-β-cyclodextrin reduces retinal cholesterol in wild-type and Cyp27a1
    El-Darzi N; Mast N; Petrov AM; Pikuleva IA
    Br J Pharmacol; 2021 Aug; 178(16):3220-3234. PubMed ID: 32698250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain.
    Liao WL; Heo GY; Dodder NG; Reem RE; Mast N; Huang S; Dipatre PL; Turko IV; Pikuleva IA
    J Proteome Res; 2011 Jan; 10(1):241-8. PubMed ID: 21049985
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.
    Bretillon L; Diczfalusy U; Björkhem I; Maire MA; Martine L; Joffre C; Acar N; Bron A; Creuzot-Garcher C
    Curr Eye Res; 2007 Apr; 32(4):361-6. PubMed ID: 17453958
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxysterols: functional significance in fetal development and the maintenance of normal retinal function.
    Javitt NB
    Curr Opin Lipidol; 2007 Jun; 18(3):283-8. PubMed ID: 17495602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential expression of cholesterol hydroxylases in Alzheimer's disease.
    Brown J; Theisler C; Silberman S; Magnuson D; Gottardi-Littell N; Lee JM; Yager D; Crowley J; Sambamurti K; Rahman MM; Reiss AB; Eckman CB; Wolozin B
    J Biol Chem; 2004 Aug; 279(33):34674-81. PubMed ID: 15148325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.
    Milagre I; Olin M; Nunes MJ; Moutinho M; Lövgren-Sandblom A; Gama MJ; Björkhem I; Rodrigues E
    Neurochem Int; 2012 Jan; 60(2):192-8. PubMed ID: 22185844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cholestenoic Acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain.
    Mast N; Reem R; Bederman I; Huang S; DiPatre PL; Bjorkhem I; Pikuleva IA
    Invest Ophthalmol Vis Sci; 2011 Jan; 52(1):594-603. PubMed ID: 20881306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cholesterol-metabolizing cytochromes P450.
    Pikuleva IA
    Drug Metab Dispos; 2006 Apr; 34(4):513-20. PubMed ID: 16434543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma.
    Fourgeux C; Bron A; Acar N; Creuzot-Garcher C; Bretillon L
    Chem Phys Lipids; 2011 Sep; 164(6):496-9. PubMed ID: 21531213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis.
    El-Darzi N; Mast N; Hammer SS; Dorweiler TF; Busik JV; Pikuleva IA
    J Lipid Res; 2023 Feb; 64(2):100323. PubMed ID: 36586438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina.
    Fourgeux C; Martine L; Acar N; Bron AM; Creuzot-Garcher CP; Bretillon L
    Biochem Biophys Res Commun; 2014 Apr; 446(3):775-81. PubMed ID: 24491555
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    El-Darzi N; Astafev A; Mast N; Saadane A; Lam M; Pikuleva IA
    Front Pharmacol; 2018; 9():827. PubMed ID: 30090064
    [No Abstract]   [Full Text] [Related]  

  • 19. Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
    Heo GY; Liao WL; Turko IV; Pikuleva IA
    Arch Biochem Biophys; 2012 Feb; 518(2):119-26. PubMed ID: 22227097
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells.
    Biswas L; Zeng Z; Graham A; Shu X
    Exp Eye Res; 2020 Feb; 191():107931. PubMed ID: 31931003
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.