BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 25068121)

  • 1. Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells.
    Rimmelé P; Bigarella CL; Liang R; Izac B; Dieguez-Gonzalez R; Barbet G; Donovan M; Brugnara C; Blander JM; Sinclair DA; Ghaffari S
    Stem Cell Reports; 2014 Jul; 3(1):44-59. PubMed ID: 25068121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells.
    Cho RH; Sieburg HB; Muller-Sieburg CE
    Blood; 2008 Jun; 111(12):5553-61. PubMed ID: 18413859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of SIRT1 inhibits hematopoietic stem cell aging and age-dependent mixed phenotype acute leukemia.
    Wang Z; Zhang C; Warden CD; Liu Z; Yuan YC; Guo C; Wang C; Wang J; Wu X; Ermel R; Vonderfecht SL; Wang X; Brown C; Forman S; Yang Y; James You M; Chen W
    Commun Biol; 2022 Apr; 5(1):396. PubMed ID: 35484199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hematopoietic Stem Cell Dynamics Are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach.
    Klose M; Florian MC; Gerbaulet A; Geiger H; Glauche I
    Stem Cells; 2019 Jul; 37(7):948-957. PubMed ID: 30897261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.
    Pang WW; Price EA; Sahoo D; Beerman I; Maloney WJ; Rossi DJ; Schrier SL; Weissman IL
    Proc Natl Acad Sci U S A; 2011 Dec; 108(50):20012-7. PubMed ID: 22123971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cells.
    Quéré R; Saint-Paul L; Carmignac V; Martin RZ; Chrétien ML; Largeot A; Hammann A; Pais de Barros JP; Bastie JN; Delva L
    Proc Natl Acad Sci U S A; 2014 Jul; 111(29):10592-7. PubMed ID: 25002492
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular mechanisms underlying lineage bias in aging hematopoiesis.
    Elias HK; Bryder D; Park CY
    Semin Hematol; 2017 Jan; 54(1):4-11. PubMed ID: 28088987
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells.
    Tsang JC; Yu Y; Burke S; Buettner F; Wang C; Kolodziejczyk AA; Teichmann SA; Lu L; Liu P
    Genome Biol; 2015 Sep; 16():178. PubMed ID: 26387834
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.
    Bigarella CL; Li J; Rimmelé P; Liang R; Sobol RW; Ghaffari S
    J Biol Chem; 2017 Feb; 292(7):3005-3015. PubMed ID: 27994057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age.
    Gekas C; Graf T
    Blood; 2013 May; 121(22):4463-72. PubMed ID: 23564910
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.
    Ergen AV; Boles NC; Goodell MA
    Blood; 2012 Mar; 119(11):2500-9. PubMed ID: 22289892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Twist-1, a novel regulator of hematopoietic stem cell self-renewal and myeloid lineage development.
    Dong CY; Liu XY; Wang N; Wang LN; Yang BX; Ren Q; Liang HY; Ma XT
    Stem Cells; 2014 Dec; 32(12):3173-82. PubMed ID: 25100001
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of stem cell aging by SIRT1 - Linking metabolic signaling to epigenetic modifications.
    Yu A; Dang W
    Mol Cell Endocrinol; 2017 Nov; 455():75-82. PubMed ID: 28392411
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.
    Sun D; Luo M; Jeong M; Rodriguez B; Xia Z; Hannah R; Wang H; Le T; Faull KF; Chen R; Gu H; Bock C; Meissner A; Göttgens B; Darlington GJ; Li W; Goodell MA
    Cell Stem Cell; 2014 May; 14(5):673-88. PubMed ID: 24792119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.
    Busch K; Klapproth K; Barile M; Flossdorf M; Holland-Letz T; Schlenner SM; Reth M; Höfer T; Rodewald HR
    Nature; 2015 Feb; 518(7540):542-6. PubMed ID: 25686605
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence.
    Kaur I; Rawal P; Rohilla S; Bhat MH; Sharma P; Siddiqui H; Kaur S
    Cell Biol Int; 2018 Sep; 42(9):1212-1220. PubMed ID: 29851177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
    Kirschner K; Chandra T; Kiselev V; Flores-Santa Cruz D; Macaulay IC; Park HJ; Li J; Kent DG; Kumar R; Pask DC; Hamilton TL; Hemberg M; Reik W; Green AR
    Cell Rep; 2017 May; 19(8):1503-1511. PubMed ID: 28538171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells.
    Kowalczyk MS; Tirosh I; Heckl D; Rao TN; Dixit A; Haas BJ; Schneider RK; Wagers AJ; Ebert BL; Regev A
    Genome Res; 2015 Dec; 25(12):1860-72. PubMed ID: 26430063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse.
    Ou X; Chae HD; Wang RH; Shelley WC; Cooper S; Taylor T; Kim YJ; Deng CX; Yoder MC; Broxmeyer HE
    Blood; 2011 Jan; 117(2):440-50. PubMed ID: 20966168
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell intrinsic alterations underlie hematopoietic stem cell aging.
    Rossi DJ; Bryder D; Zahn JM; Ahlenius H; Sonu R; Wagers AJ; Weissman IL
    Proc Natl Acad Sci U S A; 2005 Jun; 102(26):9194-9. PubMed ID: 15967997
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.