BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 25068728)

  • 1. A convenient synthesis and molecular modeling study of novel pyrazolo[3,4-d]pyrimidine and pyrazole derivatives as anti-tumor agents.
    Nassar IF; Atta-Allah SR; Elgazwy AS
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):396-405. PubMed ID: 25068728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB; Mehany ABM; Abdellatif KRA
    Anticancer Agents Med Chem; 2017; 17(10):1389-1400. PubMed ID: 28270084
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and anticancer evaluation of novel pyrazole, pyrazolo[3,4-d]pyrimidine and their glycoside derivatives.
    Nassar IF; El Farargy AF; Abdelrazek FM; Ismail NSM
    Nucleosides Nucleotides Nucleic Acids; 2017 Apr; 36(4):275-291. PubMed ID: 28323527
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives.
    Gamal-Eldeen AM; Hamdy NA; Abdel-Aziz HA; El-Hussieny EA; Fakhr IM
    Eur J Med Chem; 2014 Apr; 77():323-33. PubMed ID: 24657569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.
    Ahmed OM; Mohamed MA; Ahmed RR; Ahmed SA
    Eur J Med Chem; 2009 Sep; 44(9):3519-23. PubMed ID: 19398146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel pyrazole-5-carboxamide and pyrazole-pyrimidine derivatives: synthesis and anticancer activity.
    Shi JB; Tang WJ; Qi XB; Li R; Liu XH
    Eur J Med Chem; 2015 Jan; 90():889-96. PubMed ID: 25554922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of pyrazolo[4,3-d]pyrimidine analogues.
    Yuan L; Song C; Li C; Li Y; Dong L; Yin S
    Eur J Med Chem; 2013 Sep; 67():152-7. PubMed ID: 23851116
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, cytotoxicity, antimicrobial and anti-biofilm activities of novel pyrazolo[3,4-b]pyridine and pyrimidine functionalized 1,2,3-triazole derivatives.
    Nagender P; Malla Reddy G; Naresh Kumar R; Poornachandra Y; Ganesh Kumar C; Narsaiah B
    Bioorg Med Chem Lett; 2014 Jul; 24(13):2905-8. PubMed ID: 24835633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Some pyrazole and pyrazolo[3,4-d]pyrimidine derivatives: synthesis and anticancer evaluation.
    Shamroukh AH; Rashad AE; Abdel-Megeid RE; Ali HS; Ali MM
    Arch Pharm (Weinheim); 2014 Aug; 347(8):559-65. PubMed ID: 24801813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of novel pyrazolopyrimidines derivatives as anticancer and anti-5-lipoxygenase agents.
    Rahmouni A; Souiei S; Belkacem MA; Romdhane A; Bouajila J; Ben Jannet H
    Bioorg Chem; 2016 Jun; 66():160-8. PubMed ID: 27179178
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives.
    Hassaneen HM; Saleh FM; Abdallah TA; Mohamed MF; Mohamed YS; Awad EM; Abdelhamid IA
    Mini Rev Med Chem; 2019; 19(8):657-670. PubMed ID: 30332953
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of some novel pyrazolo[3,4-d]pyrimidine derivatives as potential antimicrobial agents.
    Holla BS; Mahalinga M; Karthikeyan MS; Akberali PM; Shetty NS
    Bioorg Med Chem; 2006 Mar; 14(6):2040-7. PubMed ID: 16310361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, antitumor activity and molecular docking study of novel benzofuran-2-yl pyrazole pyrimidine derivatives.
    El-Zahar MI; Adb El-Karim SS; Haiba ME; Khedr MA
    Acta Pol Pharm; 2011; 68(3):357-73. PubMed ID: 21648190
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 4-Substituted-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine derivatives: design, synthesis, antitumor and EGFR tyrosine kinase inhibitory activity.
    Abbas SE; Aly EI; Awadallah FM; Mahmoud WR
    Chem Biol Drug Des; 2015 May; 85(5):608-22. PubMed ID: 25318985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationship studies of pyrazolo[3,4-d]pyrimidine derivatives leading to the discovery of a novel multikinase inhibitor that potently inhibits FLT3 and VEGFR2 and evaluation of its activity against acute myeloid leukemia in vitro and in vivo.
    Yang LL; Li GB; Ma S; Zou C; Zhou S; Sun QZ; Cheng C; Chen X; Wang LJ; Feng S; Li LL; Yang SY
    J Med Chem; 2013 Feb; 56(4):1641-55. PubMed ID: 23362959
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyrosine kinase inhibition effects of novel Pyrazolo[1,5-a]pyrimidines and Pyrido[2,3-d]pyrimidines ligand: Synthesis, biological screening and molecular modeling studies.
    El Sayed MT; Hussein HAR; Elebiary NM; Hassan GS; Elmessery SM; Elsheakh AR; Nayel M; Abdel-Aziz HA
    Bioorg Chem; 2018 Aug; 78():312-323. PubMed ID: 29625271
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs.
    Attia MH; Elrazaz EZ; El-Emam SZ; Taher AT; Abdel-Aziz HA; Abouzid KAM
    Bioorg Chem; 2020 Jan; 94():103458. PubMed ID: 31785854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, anticancer assessment on human breast, liver and colon carcinoma cell lines and molecular modeling study using novel pyrazolo[4,3-c]pyridine derivatives.
    Metwally NH; Deeb EA
    Bioorg Chem; 2018 Apr; 77():203-214. PubMed ID: 29367077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity.
    Ali GME; Ibrahim DA; Elmetwali AM; Ismail NSM
    Bioorg Chem; 2019 May; 86():1-14. PubMed ID: 30682722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, antimicrobial and anti-cancer activities of some new N-ethyl, N-benzyl and N-benzoyl-3-indolyl heterocycles.
    El-Sawy ER; Mandour AH; Mahmoud K; Islam IE; Abo-Salem HM
    Acta Pharm; 2012 Jun; 62(2):157-79. PubMed ID: 22750815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.