BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 25074741)

  • 1. The behavioural response of mice lacking NK₁ receptors to guanfacine resembles its clinical profile in treatment of ADHD.
    Pillidge K; Porter AJ; Dudley JA; Tsai YC; Heal DJ; Stanford SC
    Br J Pharmacol; 2014 Oct; 171(20):4785-96. PubMed ID: 25074741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Atomoxetine reduces hyperactive/impulsive behaviours in neurokinin-1 receptor 'knockout' mice.
    Pillidge K; Porter AJ; Vasili T; Heal DJ; Stanford SC
    Pharmacol Biochem Behav; 2014 Dec; 127():56-61. PubMed ID: 25450119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The angiotensin converting enzyme inhibitor, captopril, prevents the hyperactivity and impulsivity of neurokinin-1 receptor gene 'knockout' mice: sex differences and implications for the treatment of attention deficit hyperactivity disorder.
    Porter AJ; Pillidge K; Grabowska EM; Stanford SC
    Eur Neuropsychopharmacol; 2015 Apr; 25(4):512-21. PubMed ID: 25703442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Perseveration by NK1R-/- ('knockout') mice is blunted by doses of methylphenidate that affect neither other aspects of their cognitive performance nor the behaviour of wild-type mice in the 5-Choice Continuous Performance Test.
    Pillidge K; Porter AJ; Young JW; Stanford SC
    J Psychopharmacol; 2016 Sep; 30(9):837-47. PubMed ID: 27097734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antagonism of L-type Ca(v) channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task.
    Dudley JA; Weir RK; Yan TC; Grabowska EM; Grimmé AJ; Amini S; Stephens DN; Hunt SP; Stanford SC
    Neuropharmacology; 2013 Jan; 64():329-36. PubMed ID: 22884624
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Guanfacine treatment improves ADHD phenotypes of impulsivity and hyperactivity in a neurofibromatosis type 1 mouse model.
    Lukkes JL; Drozd HP; Fitz SD; Molosh AI; Clapp DW; Shekhar A
    J Neurodev Disord; 2020 Jan; 12(1):2. PubMed ID: 31941438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A lack of functional NK1 receptors explains most, but not all, abnormal behaviours of NK1R-/- mice(1).
    Porter AJ; Pillidge K; Tsai YC; Dudley JA; Hunt SP; Peirson SN; Brown LA; Stanford SC
    Genes Brain Behav; 2015 Feb; 14(2):189-99. PubMed ID: 25558794
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences in the performance of NK1R-/- ('knockout') and wildtype mice in the 5‑Choice Continuous Performance Test.
    Porter AJ; Pillidge K; Stanford SC; Young JW
    Behav Brain Res; 2016 Feb; 298(Pt B):268-77. PubMed ID: 26522842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day.
    Yan TC; Dudley JA; Weir RK; Grabowska EM; Peña-Oliver Y; Ripley TL; Hunt SP; Stephens DN; Stanford SC
    PLoS One; 2011 Mar; 6(3):e17586. PubMed ID: 21408181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: a model of attention deficit hyperactivity disorder.
    Yan TC; Hunt SP; Stanford SC
    Neuropharmacology; 2009 Dec; 57(7-8):627-35. PubMed ID: 19748515
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The NK1R-/- mouse phenotype suggests that small body size, with a sex- and diet-dependent excess in body mass and fat, are physical biomarkers for a human endophenotype with vulnerability to attention deficit hyperactivity disorder.
    Pillidge K; Heal DJ; Stanford SC
    J Psychopharmacol; 2016 Sep; 30(9):848-55. PubMed ID: 27462087
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The influence of test experience and NK1 receptor antagonists on the performance of NK1R-/- and wild type mice in the 5-Choice Serial Reaction-Time Task.
    Weir RK; Dudley JA; Yan TC; Grabowska EM; Peña-Oliver Y; Ripley TL; Stephens DN; Stanford SC; Hunt SP
    J Psychopharmacol; 2014 Mar; 28(3):270-81. PubMed ID: 23845920
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Systemic administration of guanfacine improves food-motivated impulsive choice behavior primarily via direct stimulation of postsynaptic α
    Nishitomi K; Yano K; Kobayashi M; Jino K; Kano T; Horiguchi N; Shinohara S; Hasegawa M
    Behav Brain Res; 2018 Jun; 345():21-29. PubMed ID: 29476896
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluating Guanfacine Hydrochloride in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adult Patients: Design, Development and Place in Therapy.
    Ota T; Yamamuro K; Okazaki K; Kishimoto T
    Drug Des Devel Ther; 2021; 15():1965-1969. PubMed ID: 34007156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of postsynapse adrenergic α2A receptor improves attention/cognition performance in an animal model of attention deficit hyperactivity disorder.
    Kawaura K; Karasawa J; Chaki S; Hikichi H
    Behav Brain Res; 2014 Aug; 270():349-56. PubMed ID: 24882610
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD.
    Yan TC; McQuillin A; Thapar A; Asherson P; Hunt SP; Stanford SC; Gurling H
    J Psychopharmacol; 2010 Jan; 24(1):27-38. PubMed ID: 19204064
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cognitive Effects of Stimulant, Guanfacine, and Combined Treatment in Child and Adolescent Attention-Deficit/Hyperactivity Disorder.
    Bilder RM; Loo SK; McGough JJ; Whelan F; Hellemann G; Sugar C; Del'Homme M; Sturm A; Cowen J; Hanada G; McCracken JT
    J Am Acad Child Adolesc Psychiatry; 2016 Aug; 55(8):667-73. PubMed ID: 27453080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of d-Methylphenidate, Guanfacine, and Their Combination on Electroencephalogram Resting State Spectral Power in Attention-Deficit/Hyperactivity Disorder.
    Loo SK; Bilder RM; Cho AL; Sturm A; Cowen J; Walshaw P; Levitt J; Del'Homme M; Piacentini J; McGough JJ; McCracken JT
    J Am Acad Child Adolesc Psychiatry; 2016 Aug; 55(8):674-682.e1. PubMed ID: 27453081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential effects of ADHD medications on impulsive action in the mouse 5-choice serial reaction time task.
    Fitzpatrick CM; Andreasen JT
    Eur J Pharmacol; 2019 Mar; 847():123-129. PubMed ID: 30690006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Raised arterial blood pressure in neurokinin-1 receptor-deficient mice (NK1R(-/-) ): evidence for a neural rather than a vascular mechanism.
    Moyes AJ; Stanford SC; Hosford PS; Hobbs AJ; Ramage AG
    Exp Physiol; 2016 May; 101(5):588-98. PubMed ID: 26876733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.