BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 25078449)

  • 1. Systemic approaches identify a garlic-derived chemical, Z-ajoene, as a glioblastoma multiforme cancer stem cell-specific targeting agent.
    Jung Y; Park H; Zhao HY; Jeon R; Ryu JH; Kim WY
    Mol Cells; 2014 Jul; 37(7):547-53. PubMed ID: 25078449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Garlic Compound Z-Ajoene, S-Thiolates COX2 and STAT3 and Dampens the Inflammatory Response in RAW264.7 Macrophages.
    Hitchcock JK; Mkwanazi N; Barnett C; Graham LM; Katz AA; Hunter R; Schäfer G; Kaschula CH
    Mol Nutr Food Res; 2021 Feb; 65(3):e2000854. PubMed ID: 33274836
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma.
    Shevchenko V; Arnotskaya N; Korneyko M; Zaytsev S; Khotimchenko Y; Sharma H; Bryukhovetskiy I
    Oncol Rep; 2019 May; 41(5):3080-3088. PubMed ID: 30864699
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner.
    Prabhu VV; Allen JE; Dicker DT; El-Deiry WS
    Cancer Res; 2015 Apr; 75(7):1423-32. PubMed ID: 25712124
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells.
    Kaschula CH; Tuveri R; Ngarande E; Dzobo K; Barnett C; Kusza DA; Graham LM; Katz AA; Rafudeen MS; Parker MI; Hunter R; Schäfer G
    BMC Cancer; 2019 Mar; 19(1):248. PubMed ID: 30894168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways.
    Doan P; Musa A; Murugesan A; Sipilä V; Candeias NR; Emmert-Streib F; Ruusuvuori P; Granberg K; Yli-Harja O; Kandhavelu M
    Cells; 2020 Mar; 9(3):. PubMed ID: 32164385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sox2, a stemness gene, regulates tumor-initiating and drug-resistant properties in CD133-positive glioblastoma stem cells.
    Song WS; Yang YP; Huang CS; Lu KH; Liu WH; Wu WW; Lee YY; Lo WL; Lee SD; Chen YW; Huang PI; Chen MT
    J Chin Med Assoc; 2016 Oct; 79(10):538-45. PubMed ID: 27530866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.
    Cenciarelli C; Marei HE; Zonfrillo M; Pierimarchi P; Paldino E; Casalbore P; Felsani A; Vescovi AL; Maira G; Mangiola A
    Mol Cancer; 2014 Nov; 13():247. PubMed ID: 25380967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells.
    Liu P; Brown S; Goktug T; Channathodiyil P; Kannappan V; Hugnot JP; Guichet PO; Bian X; Armesilla AL; Darling JL; Wang W
    Br J Cancer; 2012 Oct; 107(9):1488-97. PubMed ID: 23033007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid.
    Friedman MD; Jeevan DS; Tobias M; Murali R; Jhanwar-Uniyal M
    Oncol Rep; 2013 Oct; 30(4):1645-50. PubMed ID: 23877261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
    Schreck KC; Taylor P; Marchionni L; Gopalakrishnan V; Bar EE; Gaiano N; Eberhart CG
    Clin Cancer Res; 2010 Dec; 16(24):6060-70. PubMed ID: 21169257
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties.
    Li M; Ciu JR; Ye Y; Min JM; Zhang LH; Wang K; Gares M; Cros J; Wright M; Leung-Tack J
    Carcinogenesis; 2002 Apr; 23(4):573-9. PubMed ID: 11960908
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity.
    Sunayama J; Sato A; Matsuda K; Tachibana K; Watanabe E; Seino S; Suzuki K; Narita Y; Shibui S; Sakurada K; Kayama T; Tomiyama A; Kitanaka C
    Stem Cells; 2011 Sep; 29(9):1327-37. PubMed ID: 21793107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells.
    Ma Y; Cheng Z; Liu J; Torre-Healy L; Lathia JD; Nakano I; Guo Y; Thompson RC; Freeman ML; Wang J
    Stem Cell Reports; 2017 Dec; 9(6):1948-1960. PubMed ID: 29198824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI.
    Yang YP; Chien Y; Chiou GY; Cherng JY; Wang ML; Lo WL; Chang YL; Huang PI; Chen YW; Shih YH; Chen MT; Chiou SH
    Biomaterials; 2012 Feb; 33(5):1462-76. PubMed ID: 22098779
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Z-ajoene from Crushed Garlic Alleviates Cancer-Induced Skeletal Muscle Atrophy.
    Lee H; Heo JW; Kim AR; Kweon M; Nam S; Lim JS; Sung MK; Kim SE; Ryu JH
    Nutrients; 2019 Nov; 11(11):. PubMed ID: 31717643
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activity-Based Proteomic Identification of the
    Kusza DA; Hunter R; Schäfer G; Smith M; Katz AA; Kaschula CH
    J Agric Food Chem; 2022 Nov; 70(46):14679-14692. PubMed ID: 36351177
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ajoene, a stable garlic by-product, has an antioxidant effect through Nrf2-mediated glutamate-cysteine ligase induction in HepG2 cells and primary hepatocytes.
    Kay HY; Won Yang J; Kim TH; Lee DY; Kang B; Ryu JH; Jeon R; Kim SG
    J Nutr; 2010 Jul; 140(7):1211-9. PubMed ID: 20463144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.
    Lottaz C; Beier D; Meyer K; Kumar P; Hermann A; Schwarz J; Junker M; Oefner PJ; Bogdahn U; Wischhusen J; Spang R; Storch A; Beier CP
    Cancer Res; 2010 Mar; 70(5):2030-40. PubMed ID: 20145155
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells.
    Ahmed N; Laverick L; Sammons J; Zhang H; Maslin DJ; Hassan HT
    Anticancer Res; 2001; 21(5):3519-23. PubMed ID: 11848518
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.