BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 25078633)

  • 1. Neurokinin-1 receptor antagonist orvepitant is an effective inhibitor of itch-associated response in a Mongolian gerbil model of scratching behaviour.
    Trower MK; Fisher A; Upton N; Ratti E
    Exp Dermatol; 2014 Nov; 23(11):858-60. PubMed ID: 25078633
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The NK1 receptor antagonist aprepitant attenuates NK1 agonist-induced scratching behaviour in the gerbil after intra-dermal, topical or oral administration.
    Costantini VJ; Corsi M; Dünstl G; Bettelini L; Zonzini L; Gerrard P
    Exp Dermatol; 2015 Apr; 24(4):312-4. PubMed ID: 25650546
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neurokinin-1 antagonist orvepitant for EGFRI-induced pruritus in patients with cancer: a randomised, placebo-controlled phase II trial.
    Vincenzi B; Trower M; Duggal A; Guglielmini P; Harris P; Jackson D; Lacouture ME; Ratti E; Tonini G; Wood A; Ständer S
    BMJ Open; 2020 Feb; 10(2):e030114. PubMed ID: 32034016
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Neurokinin-1 Receptor Antagonist Orvepitant Is a Novel Antitussive Therapy for Chronic Refractory Cough: Results From a Phase 2 Pilot Study (VOLCANO-1).
    Smith J; Allman D; Badri H; Miller R; Morris J; Satia I; Wood A; K Trower M
    Chest; 2020 Jan; 157(1):111-118. PubMed ID: 31421110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitory effect of the repeated treatment with Unsei-in on substance P-induced itch-associated responses through the downregulation of the expression of NK(1) tachykinin receptor in mice.
    Andoh T; Honma Y; Kawaharada S; Al-Akeel A; Nojima H; Kuraishi Y
    Biol Pharm Bull; 2003 Jun; 26(6):896-8. PubMed ID: 12808309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists.
    Sundqvist M; Kristensson E; Adolfsson R; Leffler A; Ahlstedt I; Engberg S; Drmota T; Sigfridsson K; Jussila R; de Verdier J; Novén A; Johansson A; Påhlman I; von Mentzer B; Lindström E
    Eur J Pharmacol; 2007 Dec; 577(1-3):78-86. PubMed ID: 17920583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies.
    Ratti E; Bettica P; Alexander R; Archer G; Carpenter D; Evoniuk G; Gomeni R; Lawson E; Lopez M; Millns H; Rabiner EA; Trist D; Trower M; Zamuner S; Krishnan R; Fava M
    J Psychopharmacol; 2013 May; 27(5):424-34. PubMed ID: 23539641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.
    Di Fabio R; Alvaro G; Braggio S; Carletti R; Gerrard PA; Griffante C; Marchioro C; Pozzan A; Melotto S; Poffe A; Piccoli L; Ratti E; Tranquillini E; Trower M; Spada S; Corsi M
    Bioorg Med Chem; 2013 Nov; 21(21):6264-73. PubMed ID: 24075145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti pruritic effects of topical crotamiton, capsaicin, and a corticosteroid on pruritogen-induced scratching behavior.
    Sekine R; Satoh T; Takaoka A; Saeki K; Yokozeki H
    Exp Dermatol; 2012 Mar; 21(3):201-4. PubMed ID: 22379965
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blockade of cannabinoid CB1 and CB2 receptors does not prevent the antipruritic effect of systemic paracetamol.
    Saglam G; Gunduz O; Ulugol A
    Acta Neurol Belg; 2014 Dec; 114(4):307-9. PubMed ID: 24399199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-emetic activity of the novel nonpeptide tachykinin NK1 receptor antagonist ezlopitant (CJ-11,974) against acute and delayed cisplatin-induced emesis in the ferret.
    Tsuchiya M; Fujiwara Y; Kanai Y; Mizutani M; Shimada K; Suga O; Ueda S; Watson JW; Nagahisa A
    Pharmacology; 2002 Nov; 66(3):144-52. PubMed ID: 12372904
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitric oxide enhances substance P-induced itch-associated responses in mice.
    Andoh T; Kuraishi Y
    Br J Pharmacol; 2003 Jan; 138(1):202-8. PubMed ID: 12522091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substance P and neurokinin 1 receptor are new targets for the treatment of chronic pruritus.
    Ständer S; Yosipovitch G
    Br J Dermatol; 2019 Nov; 181(5):932-938. PubMed ID: 31016733
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom.
    Costa SK; Starr A; Hyslop S; Gilmore D; Brain SD
    Vascul Pharmacol; 2006 Oct; 45(4):209-14. PubMed ID: 16914387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.
    Togashi Y; Umeuchi H; Okano K; Ando N; Yoshizawa Y; Honda T; Kawamura K; Endoh T; Utsumi J; Kamei J; Tanaka T; Nagase H
    Eur J Pharmacol; 2002 Jan; 435(2-3):259-64. PubMed ID: 11821035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycyrrhetinic acid prevents cutaneous scratching behavior in mice elicited by substance P or PAR-2 agonist.
    Akasaka Y; Yoshida T; Tsukahara M; Hatta A; Inoue H
    Eur J Pharmacol; 2011 Nov; 670(1):175-9. PubMed ID: 21925497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 5-HT3 receptors antagonists reduce serotonin-induced scratching in mice.
    Ostadhadi S; Kordjazy N; Haj-Mirzaian A; Mansouri P; Dehpour AR
    Fundam Clin Pharmacol; 2015 Jun; 29(3):310-5. PubMed ID: 25711853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the chloroquine-induced mouse model of pruritus using an automated behavioural system.
    Tarrasón G; Carcasona C; Eichhorn P; Pérez B; Gavaldà A; Godessart N
    Exp Dermatol; 2017 Nov; 26(11):1105-1111. PubMed ID: 28605064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils.
    Nordquist RE; Durkin S; Jacquet A; Spooren W
    Eur J Pharmacol; 2008 Dec; 600(1-3):87-92. PubMed ID: 18930726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-specific effects of the tachykinin NK1 receptor antagonist, CP-99,994, in antinociceptive tests in rat, mouse and gerbil.
    Smith G; Harrison S; Bowers J; Wiseman J; Birch P
    Eur J Pharmacol; 1994 Dec; 271(2-3):481-7. PubMed ID: 7705448
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.