These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 25079510)

  • 1. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19.
    Elshahawi SI; Ramelot TA; Seetharaman J; Chen J; Singh S; Yang Y; Pederson K; Kharel MK; Xiao R; Lew S; Yennamalli RM; Miller MD; Wang F; Tong L; Montelione GT; Kennedy MA; Bingman CA; Zhu H; Phillips GN; Thorson JS
    ACS Chem Biol; 2014 Oct; 9(10):2347-58. PubMed ID: 25079510
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural insight into the self-sacrifice mechanism of enediyne resistance.
    Singh S; Hager MH; Zhang C; Griffith BR; Lee MS; Hallenga K; Markley JL; Thorson JS
    ACS Chem Biol; 2006 Aug; 1(7):451-60. PubMed ID: 17168523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The calicheamicin gene cluster and its iterative type I enediyne PKS.
    Ahlert J; Shepard E; Lomovskaya N; Zazopoulos E; Staffa A; Bachmann BO; Huang K; Fonstein L; Czisny A; Whitwam RE; Farnet CM; Thorson JS
    Science; 2002 Aug; 297(5584):1173-6. PubMed ID: 12183629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710.
    Gao Q; Thorson JS
    FEMS Microbiol Lett; 2008 May; 282(1):105-14. PubMed ID: 18328078
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resistance to Enediyne Antitumor Antibiotics by Sequestration.
    Chang CY; Yan X; Crnovcic I; Annaval T; Chang C; Nocek B; Rudolf JD; Yang D; Hindra ; Babnigg G; Joachimiak A; Phillips GN; Shen B
    Cell Chem Biol; 2018 Sep; 25(9):1075-1085.e4. PubMed ID: 29937405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance to enediyne antitumor antibiotics by CalC self-sacrifice.
    Biggins JB; Onwueme KC; Thorson JS
    Science; 2003 Sep; 301(5639):1537-41. PubMed ID: 12970566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conditions for protoplasting, regenerating, and transforming the calicheamicin producer, Micromonospora echinospora.
    Love SF; Maiese WM; Rothstein DM
    Appl Environ Microbiol; 1992 Apr; 58(4):1376-8. PubMed ID: 1599256
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina.
    Kosgei AJ; Miller MD; Bhardwaj M; Xu W; Thorson JS; Van Lanen SG; Phillips GN
    Acta Crystallogr F Struct Biol Commun; 2022 Jan; 78(Pt 1):1-7. PubMed ID: 34981769
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora.
    Song H; Xu R; Guo Z
    Chembiochem; 2015 Jan; 16(1):100-9. PubMed ID: 25404066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular cloning and characterization of a 2-deoxystreptamine biosynthetic gene cluster in gentamicin-producing Micromonospora echinospora ATCC15835.
    Kharel MK; Basnet DB; Lee HC; Liou K; Moon YH; Kim JJ; Woo JS; Sohng JK
    Mol Cells; 2004 Aug; 18(1):71-8. PubMed ID: 15359126
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the biosynthetic gene cluster for maklamicin, a spirotetronate-class antibiotic of the endophytic Micromonospora sp. NBRC 110955.
    Daduang R; Kitani S; Hashimoto J; Thamchaipenet A; Igarashi Y; Shin-ya K; Ikeda H; Nihira T
    Microbiol Res; 2015 Nov; 180():30-9. PubMed ID: 26505309
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes.
    Horsman GP; Chen Y; Thorson JS; Shen B
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11331-5. PubMed ID: 20534556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.
    Yan X; Chen JJ; Adhikari A; Yang D; Crnovcic I; Wang N; Chang CY; Rader C; Shen B
    Org Lett; 2017 Nov; 19(22):6192-6195. PubMed ID: 29086572
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties.
    Maiese WM; Lechevalier MP; Lechevalier HA; Korshalla J; Kuck N; Fantini A; Wildey MJ; Thomas J; Greenstein M
    J Antibiot (Tokyo); 1989 Apr; 42(4):558-63. PubMed ID: 2722671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
    Van Lanen SG; Oh TJ; Liu W; Wendt-Pienkowski E; Shen B
    J Am Chem Soc; 2007 Oct; 129(43):13082-94. PubMed ID: 17918933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.
    Savic M; Ilic-Tomic T; Macmaster R; Vasiljevic B; Conn GL
    J Bacteriol; 2008 Sep; 190(17):5855-61. PubMed ID: 18586937
    [TBL] [Abstract][Full Text] [Related]  

  • 17. C-N-Coupled Metabolites Yield Insights into Dynemicin A Biosynthesis.
    Cohen DR; Townsend CA
    Chembiochem; 2020 Aug; 21(15):2137-2142. PubMed ID: 32198800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the biosynthetic gene cluster for the oligosaccharide antibiotic, Evernimicin, in Micromonospora carbonacea var. africana ATCC39149.
    Hosted TJ; Wang TX; Alexander DC; Horan AC
    J Ind Microbiol Biotechnol; 2001 Dec; 27(6):386-92. PubMed ID: 11774004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research.
    Thorson JS; Sievers EL; Ahlert J; Shepard E; Whitwam RE; Onwueme KC; Ruppen M
    Curr Pharm Des; 2000 Dec; 6(18):1841-79. PubMed ID: 11102565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.
    Rudolf JD; Yan X; Shen B
    J Ind Microbiol Biotechnol; 2016 Mar; 43(2-3):261-76. PubMed ID: 26318027
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.