BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 25079698)

  • 1. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids.
    Vickers CJ; González-Páez GE; Litwin KM; Umotoy JC; Coutsias EA; Wolan DW
    ACS Chem Biol; 2014 Oct; 9(10):2194-8. PubMed ID: 25079698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective detection of caspase-3 versus caspase-7 using activity-based probes with key unnatural amino acids.
    Vickers CJ; González-Páez GE; Wolan DW
    ACS Chem Biol; 2013 Jul; 8(7):1558-66. PubMed ID: 23614665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In Vitro Use of Peptide Based Substrates and Inhibitors of Apoptotic Caspases.
    McStay GP
    Methods Mol Biol; 2016; 1419():57-67. PubMed ID: 27108431
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of a highly selective caspase-3 substrate for imaging live cells.
    Vickers CJ; González-Páez GE; Wolan DW
    ACS Chem Biol; 2014 Oct; 9(10):2199-203. PubMed ID: 25133295
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
    Vickers CJ; González-Páez GE; Wolan DW
    J Am Chem Soc; 2013 Aug; 135(34):12869-76. PubMed ID: 23915420
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.
    Kent CR; Bryja M; Gustafson HA; Kawarski MY; Lenti G; Pierce EN; Knopp RC; Ceja V; Pati B; Walters DE; Karver CE
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5476-5480. PubMed ID: 27777011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small Molecule Active Site Directed Tools for Studying Human Caspases.
    Poreba M; Szalek A; Kasperkiewicz P; Rut W; Salvesen GS; Drag M
    Chem Rev; 2015 Nov; 115(22):12546-629. PubMed ID: 26551511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates.
    Poreba M; Kasperkiewicz P; Snipas SJ; Fasci D; Salvesen GS; Drag M
    Cell Death Differ; 2014 Sep; 21(9):1482-92. PubMed ID: 24832467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.
    Chu W; Zhang J; Zeng C; Rothfuss J; Tu Z; Chu Y; Reichert DE; Welch MJ; Mach RH
    J Med Chem; 2005 Dec; 48(24):7637-47. PubMed ID: 16302804
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes.
    Berger AB; Witte MD; Denault JB; Sadaghiani AM; Sexton KM; Salvesen GS; Bogyo M
    Mol Cell; 2006 Aug; 23(4):509-21. PubMed ID: 16916639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.
    Schroeder T; Barandun J; Flütsch A; Briand C; Mittl PR; Grütter MG
    Structure; 2013 Feb; 21(2):277-89. PubMed ID: 23333429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A substrate-phage approach for investigating caspase specificity.
    Lien S; Pastor R; Sutherlin D; Lowman HB
    Protein J; 2004 Aug; 23(6):413-25. PubMed ID: 15517988
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score.
    Yoshimori A; Takasawa R; Tanuma S
    BMC Pharmacol; 2004 May; 4():7. PubMed ID: 15154972
    [TBL] [Abstract][Full Text] [Related]  

  • 14. General in vitro caspase assay procedures.
    Boucher D; Duclos C; Denault JB
    Methods Mol Biol; 2014; 1133():3-39. PubMed ID: 24567092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise.
    Flütsch A; Ackermann R; Schroeder T; Lukarska M; Hausammann GJ; Weinert C; Briand C; Grütter MG
    Biochem J; 2014 Jul; 461(2):279-90. PubMed ID: 24779913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Caspase-6 and neurodegeneration.
    Graham RK; Ehrnhoefer DE; Hayden MR
    Trends Neurosci; 2011 Dec; 34(12):646-56. PubMed ID: 22018804
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase selective reagents for diagnosing apoptotic mechanisms.
    Poreba M; Groborz K; Navarro M; Snipas SJ; Drag M; Salvesen GS
    Cell Death Differ; 2019 Feb; 26(2):229-244. PubMed ID: 29748600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the novel substrates for caspase-6 in apoptosis using proteomic approaches.
    Cho JH; Lee PY; Son WC; Chi SW; Park BC; Kim JH; Park SG
    BMB Rep; 2013 Dec; 46(12):588-93. PubMed ID: 24195789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases.
    Abhari BA; Davoodi J
    J Mol Biol; 2008 Sep; 381(3):645-54. PubMed ID: 18619610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells.
    Groborz K; Gonzalez Ramirez ML; Snipas SJ; Salvesen GS; Drąg M; Poręba M
    Cell Death Differ; 2020 Feb; 27(2):451-465. PubMed ID: 31209360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.