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4. N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line. Parekh RB; Dwek RA; Rudd PM; Thomas JR; Rademacher TW; Warren T; Wun TC; Hebert B; Reitz B; Palmier M Biochemistry; 1989 Sep; 28(19):7670-9. PubMed ID: 2514793 [TBL] [Abstract][Full Text] [Related]
5. Construction and expression of hybrid plasminogen activators prepared from tissue-type plasminogen activator and urokinase-type plasminogen activator genes. Lee SG; Kalyan N; Wilhelm J; Hum WT; Rappaport R; Cheng SM; Dheer S; Urbano C; Hartzell RW; Ronchetti-Blume M J Biol Chem; 1988 Feb; 263(6):2917-24. PubMed ID: 3125172 [TBL] [Abstract][Full Text] [Related]
6. Characterization of domain deletion and/or duplication mutants of a recombinant chimera of tissue-type plasminogen activator and urokinase-type plasminogen activator (rt-PA/u-PA). Nelles L; Lijnen HR; Van Nuffelen A; Demarsin E; Collen D Thromb Haemost; 1990 Aug; 64(1):53-60. PubMed ID: 2148847 [TBL] [Abstract][Full Text] [Related]
7. Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture. Rijken DC; Collen D J Biol Chem; 1981 Jul; 256(13):7035-41. PubMed ID: 6787058 [TBL] [Abstract][Full Text] [Related]
8. Comparative thrombolytic properties of tissue-type plasminogen activator and of a plasminogen activator inhibitor-1-resistant glycosylation variant, in a combined arterial and venous thrombosis model in the dog. Collen D; Stassen JM; Yasuda T; Refino C; Paoni N; Keyt B; Roskams T; Guerrero JL; Lijnen HR; Gold HK Thromb Haemost; 1994 Jul; 72(1):98-104. PubMed ID: 7974384 [TBL] [Abstract][Full Text] [Related]
9. Characterization of a modified human tissue plasminogen activator comprising a kringle-2 and a protease domain. Burck PJ; Berg DH; Warrick MW; Berg DT; Walls JD; Jaskunas SR; Crisel RM; Weigel B; Vlahos CJ; McClure DB J Biol Chem; 1990 Mar; 265(9):5170-7. PubMed ID: 2108167 [TBL] [Abstract][Full Text] [Related]
10. On the molecular interactions between fibrin, tissue-type plasminogen activator and plasminogen. Lijnen HR; Van Hoef B; Collen D Thromb Res Suppl; 1990; 10():45-54. PubMed ID: 2107598 [TBL] [Abstract][Full Text] [Related]
11. Biological properties of hybrid plasminogen activators. Hung PP; Wilhelm J; Kalyan NK; Cheng SM; James HL; Nachowiak D; Weinheimer CJ; Sobel BE; Bergmann SR; Lee SG Adv Exp Med Biol; 1990; 281():201-8. PubMed ID: 2129369 [TBL] [Abstract][Full Text] [Related]
12. Biochemical, thrombolytic and pharmacokinetic properties of rt-PA P47G, K49N, a substitution variant of human tissue-type plasminogen activator. Nelles L; Li XK; Vanlinthout I; De Cock F; Lijnen HR; Collen D Thromb Haemost; 1992 Apr; 67(4):445-52. PubMed ID: 1631793 [TBL] [Abstract][Full Text] [Related]
13. Transgenic expression of a variant of human tissue-type plasminogen activator in goat milk: purification and characterization of the recombinant enzyme. Denman J; Hayes M; O'Day C; Edmunds T; Bartlett C; Hirani S; Ebert KM; Gordon K; McPherson JM Biotechnology (N Y); 1991 Sep; 9(9):839-43. PubMed ID: 1367545 [TBL] [Abstract][Full Text] [Related]
14. Stimulation by fibrinogen of the amidolytic activity of single-chain tissue plasminogen activator. Urano T; deSerrano VS; Urano S; Castellino FJ Arch Biochem Biophys; 1989 Apr; 270(1):356-62. PubMed ID: 2494944 [TBL] [Abstract][Full Text] [Related]
15. Biochemical and biological properties of a recombinant tissue-type plasminogen activator derived from the rat JMI-229 cell line. Lijnen HR; Webb PD; Van Hoef B; De Cock F; Stassen JM; Prior SD; Collen D Thromb Haemost; 1992 Feb; 67(2):239-47. PubMed ID: 1621244 [TBL] [Abstract][Full Text] [Related]
16. The effector roles of kringle 1 and kringle 2 in the enzymatic properties of recombinant tissue-type plasminogen activator as revealed by generation of recombinant molecules containing each kringle linked to the protease domain. Rydzewski A; Castellino FJ Arch Biochem Biophys; 1993 Jan; 300(1):472-82. PubMed ID: 8424682 [TBL] [Abstract][Full Text] [Related]
17. In vivo distribution of Tc-99m labeled recombinant tissue-type plasminogen activator in control and thrombus-bearing rats. Tsukamoto E Ann Nucl Med; 1992 Aug; 6(3):177-84. PubMed ID: 1389893 [TBL] [Abstract][Full Text] [Related]
20. Effect of retraction on the lysis of human clots with fibrin specific and non-fibrin specific plasminogen activators. Sabovic M; Lijnen HR; Keber D; Collen D Thromb Haemost; 1989 Dec; 62(4):1083-7. PubMed ID: 2515603 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]