BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 25092689)

  • 1. Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives.
    Corona A; Di Leva FS; Thierry S; Pescatori L; Cuzzucoli Crucitti G; Subra F; Delelis O; Esposito F; Rigogliuso G; Costi R; Cosconati S; Novellino E; Di Santo R; Tramontano E
    Antimicrob Agents Chemother; 2014 Oct; 58(10):6101-10. PubMed ID: 25092689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
    Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
    Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H.
    Corona A; di Leva FS; Rigogliuso G; Pescatori L; Madia VN; Subra F; Delelis O; Esposito F; Cadeddu M; Costi R; Cosconati S; Novellino E; di Santo R; Tramontano E
    Antiviral Res; 2016 Oct; 134():236-243. PubMed ID: 27659398
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
    Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
    Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 RNase H inhibitors.
    Corona A; Schneider A; Schweimer K; Rösch P; Wöhrl BM; Tramontano E
    Antimicrob Agents Chemother; 2014 Jul; 58(7):4086-93. PubMed ID: 24798282
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase.
    Messore A; Corona A; Madia VN; Saccoliti F; Tudino V; De Leo A; Ialongo D; Scipione L; De Vita D; Amendola G; Novellino E; Cosconati S; Métifiot M; Andreola ML; Esposito F; Grandi N; Tramontano E; Costi R; Di Santo R
    J Med Chem; 2021 Jun; 64(12):8579-8598. PubMed ID: 34106711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach.
    Costi R; Métifiot M; Esposito F; Cuzzucoli Crucitti G; Pescatori L; Messore A; Scipione L; Tortorella S; Zinzula L; Novellino E; Pommier Y; Tramontano E; Marchand C; Di Santo R
    J Med Chem; 2013 Nov; 56(21):8588-98. PubMed ID: 24124919
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.
    Messore A; Corona A; Madia VN; Saccoliti F; Tudino V; De Leo A; Scipione L; De Vita D; Amendola G; Di Maro S; Novellino E; Cosconati S; Métifiot M; Andreola ML; Valenti P; Esposito F; Grandi N; Tramontano E; Costi R; Di Santo R
    ACS Med Chem Lett; 2020 May; 11(5):798-805. PubMed ID: 32435387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid.
    Shaw-Reid CA; Munshi V; Graham P; Wolfe A; Witmer M; Danzeisen R; Olsen DB; Carroll SS; Embrey M; Wai JS; Miller MD; Cole JL; Hazuda DJ
    J Biol Chem; 2003 Jan; 278(5):2777-80. PubMed ID: 12480948
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase.
    Pescatori L; Métifiot M; Chung S; Masoaka T; Cuzzucoli Crucitti G; Messore A; Pupo G; Madia VN; Saccoliti F; Scipione L; Tortorella S; Di Leva FS; Cosconati S; Marinelli L; Novellino E; Le Grice SF; Pommier Y; Marchand C; Costi R; Di Santo R
    J Med Chem; 2015 Jun; 58(11):4610-23. PubMed ID: 25961960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication.
    Corona A; Onnis V; Del Vecchio C; Esposito F; Cheng YC; Tramontano E
    Molecules; 2020 Mar; 25(6):. PubMed ID: 32183488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The nature of the N-terminal amino acid residue of HIV-1 RNase H is critical for the stability of reverse transcriptase in viral particles.
    Boso G; Örvell C; Somia NV
    J Virol; 2015 Jan; 89(2):1286-97. PubMed ID: 25392207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.
    Esposito F; Mandrone M; Del Vecchio C; Carli I; Distinto S; Corona A; Lianza M; Piano D; Tacchini M; Maccioni E; Cottiglia F; Saccon E; Poli F; Parolin C; Tramontano E
    Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28637198
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting HIV-1 RNase H:
    Corona A; Ballana E; Distinto S; Rogolino D; Del Vecchio C; Carcelli M; Badia R; Riveira-Muñoz E; Esposito F; Parolin C; Esté JA; Grandi N; Tramontano E
    Viruses; 2020 Jul; 12(7):. PubMed ID: 32640577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
    Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
    Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones.
    Arion D; Sluis-Cremer N; Min KL; Abram ME; Fletcher RS; Parniak MA
    J Biol Chem; 2002 Jan; 277(2):1370-4. PubMed ID: 11684697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
    Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
    Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
    Tang J; Vernekar SKV; Chen YL; Miller L; Huber AD; Myshakina N; Sarafianos SG; Parniak MA; Wang Z
    Eur J Med Chem; 2017 Jun; 133():85-96. PubMed ID: 28384548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Construction of an enzymatically active ribonuclease H domain of human immunodeficiency virus type 1 reverse transcriptase.
    Stahl SJ; Kaufman JD; Vikić-Topić S; Crouch RJ; Wingfield PT
    Protein Eng; 1994 Sep; 7(9):1103-8. PubMed ID: 7530360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance.
    Delviks-Frankenberry KA; Nikolenko GN; Barr R; Pathak VK
    J Virol; 2007 Jul; 81(13):6837-45. PubMed ID: 17428874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.