BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 25096297)

  • 1. Design, synthesis and in vitro evaluation of novel uni- and bivalent ligands for the cannabinoid receptor type 1 with variation of spacer length and structure.
    Huang G; Pemp D; Stadtmüller P; Nimczick M; Heilmann J; Decker M
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4209-14. PubMed ID: 25096297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.
    Espinosa-Bustos C; Lagos CF; Romero-Parra J; Zárate AM; Mella-Raipán J; Pessoa-Mahana H; Recabarren-Gajardo G; Iturriaga-Vásquez P; Tapia RA; Pessoa-Mahana CD
    Arch Pharm (Weinheim); 2015 Feb; 348(2):81-8. PubMed ID: 25641513
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of bivalent cannabinoid receptor ligands based on hCB₂R selective benzimidazoles reveal unexpected intrinsic properties.
    Nimczick M; Pemp D; Darras FH; Chen X; Heilmann J; Decker M
    Bioorg Med Chem; 2014 Aug; 22(15):3938-46. PubMed ID: 24984935
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease.
    González-Naranjo P; Pérez-Macias N; Campillo NE; Pérez C; Arán VJ; Girón R; Sánchez-Robles E; Martín MI; Gómez-Cañas M; García-Arencibia M; Fernández-Ruiz J; Páez JA
    Eur J Med Chem; 2014 Feb; 73():56-72. PubMed ID: 24378710
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New approaches in the design and development of cannabinoid receptor ligands: multifunctional and bivalent compounds.
    Nimczick M; Decker M
    ChemMedChem; 2015 May; 10(5):773-86. PubMed ID: 25820617
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Contrasting effects of different cannabinoid receptor ligands on mouse ingestive behaviour.
    Grey J; Terry P; Higgs S
    Behav Pharmacol; 2012 Sep; 23(5-6):551-9. PubMed ID: 22772336
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.
    Garai S; Schaffer PC; Laprairie RB; Janero DR; Pertwee RG; Straiker A; Thakur GA
    Bioorg Med Chem; 2021 Nov; 50():116421. PubMed ID: 34634617
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Description of a bivalent cannabinoid ligand with hypophagic properties.
    Fernández-Fernández C; Decara J; Bermúdez-Silva FJ; Sánchez E; Morales P; Gómez-Cañas M; Gómez-Ruíz M; Callado LF; Goya P; Rodríguez de Fonseca F; Martín MI; Fernández-Ruíz J; Meana JJ; Jagerovic N
    Arch Pharm (Weinheim); 2013 Mar; 346(3):171-9. PubMed ID: 23371794
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors.
    Pasquini S; De Rosa M; Ligresti A; Mugnaini C; Brizzi A; Caradonna NP; Cascio MG; Bolognini D; Pertwee RG; Di Marzo V; Corelli F
    Eur J Med Chem; 2012 Dec; 58():30-43. PubMed ID: 23085772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists.
    Rempel V; Volz N; Hinz S; Karcz T; Meliciani I; Nieger M; Wenzel W; Bräse S; Müller CE
    J Med Chem; 2012 Sep; 55(18):7967-77. PubMed ID: 22916707
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists.
    Kiyoi T; York M; Francis S; Edwards D; Walker G; Houghton AK; Cottney JE; Baker J; Adam JM
    Bioorg Med Chem Lett; 2010 Aug; 20(16):4918-21. PubMed ID: 20634067
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
    Janero DR; Yaddanapudi S; Zvonok N; Subramanian KV; Shukla VG; Stahl E; Zhou L; Hurst D; Wager-Miller J; Bohn LM; Reggio PH; Mackie K; Makriyannis A
    ACS Chem Neurosci; 2015 Aug; 6(8):1400-10. PubMed ID: 25978068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes.
    Taher AT; Kadry HH; Allarà M; Di Marzo V; Abadi AH; Abouzid KA
    J Enzyme Inhib Med Chem; 2013 Jun; 28(3):436-9. PubMed ID: 22214210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging.
    Donohue SR; Halldin C; Pike VW
    Bioorg Med Chem; 2006 Jun; 14(11):3712-20. PubMed ID: 16466922
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists.
    Aghazadeh Tabrizi M; Baraldi PG; Saponaro G; Moorman AR; Romagnoli R; Preti D; Baraldi S; Ruggiero E; Tintori C; Tuccinardi T; Vincenzi F; Borea PA; Varani K
    J Med Chem; 2013 Jun; 56(11):4482-96. PubMed ID: 23697626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.
    Song KS; Lee SH; Chun HJ; Kim JY; Jung ME; Ahn K; Kim SU; Kim J; Lee J
    Bioorg Med Chem; 2008 Apr; 16(7):4035-51. PubMed ID: 18243711
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel sterically hindered cannabinoid CB1 receptor ligands.
    Urbani P; Cascio MG; Ramunno A; Bisogno T; Saturnino C; Di Marzo V
    Bioorg Med Chem; 2008 Aug; 16(15):7510-5. PubMed ID: 18579386
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.
    Vasiljevik T; Franks LN; Ford BM; Douglas JT; Prather PL; Fantegrossi WE; Prisinzano TE
    J Med Chem; 2013 Jun; 56(11):4537-50. PubMed ID: 23631463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB
    Pike E; Grafinger KE; Cannaert A; Ametovski A; Luo JL; Sparkes E; Cairns EA; Ellison R; Gerona R; Stove CP; Auwärter V; Banister SD
    Drug Test Anal; 2021 Jul; 13(7):1383-1401. PubMed ID: 33787091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA.
    Banister SD; Adams A; Kevin RC; Macdonald C; Glass M; Boyd R; Connor M; McGregor IS; Havel CM; Bright SJ; Vilamala MV; Lladanosa CG; Barratt MJ; Gerona RR
    Drug Test Anal; 2019 Feb; 11(2):279-291. PubMed ID: 30151911
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.