BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 25100850)

  • 1. A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses.
    Deng X; Agnihothram S; Mielech AM; Nichols DB; Wilson MW; StJohn SE; Larsen SD; Mesecar AD; Lenschow DJ; Baric RS; Baker SC
    J Virol; 2014 Oct; 88(20):11825-33. PubMed ID: 25100850
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus.
    Báez-Santos YM; Mielech AM; Deng X; Baker S; Mesecar AD
    J Virol; 2014 Nov; 88(21):12511-27. PubMed ID: 25142582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
    Báez-Santos YM; St John SE; Mesecar AD
    Antiviral Res; 2015 Mar; 115():21-38. PubMed ID: 25554382
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme.
    Békés M; Rut W; Kasperkiewicz P; Mulder MP; Ovaa H; Drag M; Lima CD; Huang TT
    Biochem J; 2015 Jun; 468(2):215-26. PubMed ID: 25764917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
    Daczkowski CM; Goodwin OY; Dzimianski JV; Farhat JJ; Pegan SD
    J Virol; 2017 Dec; 91(23):. PubMed ID: 28931677
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV‑2 papain-like protease.
    Zou Z; Shan H; Sun D; Xia L; Shi Y; Wan J; Zhou A; Wu Y; Xu H; Lei H; Xu Z; Wu Y
    Acta Biochim Biophys Sin (Shanghai); 2022 Aug; 54(8):1133-1139. PubMed ID: 35866602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.
    van Huizen M; Bloeme-Ter Horst JR; de Gruyter HLM; Geurink PP; van der Heden van Noort GJ; Knaap RCM; Nelemans T; Ogando NS; Leijs AA; Urakova N; Mark BL; Snijder EJ; Myeni SK; Kikkert M
    PLoS Pathog; 2024 Mar; 20(3):e1012100. PubMed ID: 38527094
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease.
    Yang X; Chen X; Bian G; Tu J; Xing Y; Wang Y; Chen Z
    J Gen Virol; 2014 Mar; 95(Pt 3):614-626. PubMed ID: 24362959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.
    Srinivasan V; Brognaro H; Prabhu PR; de Souza EE; Günther S; Reinke PYA; Lane TJ; Ginn H; Han H; Ewert W; Sprenger J; Koua FHM; Falke S; Werner N; Andaleeb H; Ullah N; Franca BA; Wang M; Barra ALC; Perbandt M; Schwinzer M; Schmidt C; Brings L; Lorenzen K; Schubert R; Machado RRG; Candido ED; Oliveira DBL; Durigon EL; Niebling S; Garcia AS; Yefanov O; Lieske J; Gelisio L; Domaracky M; Middendorf P; Groessler M; Trost F; Galchenkova M; Mashhour AR; Saouane S; Hakanpää J; Wolf M; Alai MG; Turk D; Pearson AR; Chapman HN; Hinrichs W; Wrenger C; Meents A; Betzel C
    Commun Biol; 2022 Aug; 5(1):805. PubMed ID: 35953531
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity.
    Barretto N; Jukneliene D; Ratia K; Chen Z; Mesecar AD; Baker SC
    J Virol; 2005 Dec; 79(24):15189-98. PubMed ID: 16306590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MERS-CoV papain-like protease has deISGylating and deubiquitinating activities.
    Mielech AM; Kilianski A; Baez-Santos YM; Mesecar AD; Baker SC
    Virology; 2014 Feb; 450-451():64-70. PubMed ID: 24503068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme.
    Lindner HA; Fotouhi-Ardakani N; Lytvyn V; Lachance P; Sulea T; Ménard R
    J Virol; 2005 Dec; 79(24):15199-208. PubMed ID: 16306591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
    Clasman JR; Everett RK; Srinivasan K; Mesecar AD
    Antiviral Res; 2020 Feb; 174():104661. PubMed ID: 31765674
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activities.
    Mielech AM; Chen Y; Mesecar AD; Baker SC
    Virus Res; 2014 Dec; 194():184-90. PubMed ID: 24512893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors.
    Kilianski A; Mielech AM; Deng X; Baker SC
    J Virol; 2013 Nov; 87(21):11955-62. PubMed ID: 23986593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Therapeutic potential of metal ions for COVID-19: insights from the papain-like protease of SARS-CoV-2.
    Shetler CL; Ferreira JC; Cardoso THS; Silva EMA; Saksena NK; Rabeh WM
    Biochem J; 2022 Oct; 479(20):2175-2193. PubMed ID: 36205308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease.
    Freitas BT; Durie IA; Murray J; Longo JE; Miller HC; Crich D; Hogan RJ; Tripp RA; Pegan SD
    ACS Infect Dis; 2020 Aug; 6(8):2099-2109. PubMed ID: 32428392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease.
    Nayak D; Dos Santos Bury P; Drag M; Nijkerk AN; El Oualid F; Olsen SK
    Methods Mol Biol; 2023; 2591():171-188. PubMed ID: 36350549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15).
    Gold IM; Reis N; Glaser F; Glickman MH
    Semin Cell Dev Biol; 2022 Dec; 132():16-26. PubMed ID: 35764457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unraveling the Molecular Mechanism of Recognition of Human Interferon-Stimulated Gene Product 15 by Coronavirus Papain-Like Proteases: A Multiscale Simulation Study.
    Roy R; Jonniya NA; Poddar S; Sk MF; Kar P
    J Chem Inf Model; 2021 Dec; 61(12):6038-6052. PubMed ID: 34784198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.