These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
839 related articles for article (PubMed ID: 25101824)
1. The cellular thermal shift assay for evaluating drug target interactions in cells. Jafari R; Almqvist H; Axelsson H; Ignatushchenko M; Lundbäck T; Nordlund P; Martinez Molina D Nat Protoc; 2014 Sep; 9(9):2100-22. PubMed ID: 25101824 [TBL] [Abstract][Full Text] [Related]
2. Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay. Seashore-Ludlow B; Axelsson H; Almqvist H; Dahlgren B; Jonsson M; Lundbäck T Biochemistry; 2018 Dec; 57(48):6715-6725. PubMed ID: 30418016 [TBL] [Abstract][Full Text] [Related]
3. A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1. McNulty DE; Bonnette WG; Qi H; Wang L; Ho TF; Waszkiewicz A; Kallal LA; Nagarajan RP; Stern M; Quinn AM; Creasy CL; Su DS; Graves AP; Annan RS; Sweitzer SM; Holbert MA SLAS Discov; 2018 Jan; 23(1):34-46. PubMed ID: 28957646 [TBL] [Abstract][Full Text] [Related]
4. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Martinez Molina D; Jafari R; Ignatushchenko M; Seki T; Larsson EA; Dan C; Sreekumar L; Cao Y; Nordlund P Science; 2013 Jul; 341(6141):84-7. PubMed ID: 23828940 [TBL] [Abstract][Full Text] [Related]
5. CETSA and thermal proteome profiling strategies for target identification and drug discovery of natural products. Tu Y; Tan L; Tao H; Li Y; Liu H Phytomedicine; 2023 Jul; 116():154862. PubMed ID: 37216761 [TBL] [Abstract][Full Text] [Related]
6. CETSA: a target engagement assay with potential to transform drug discovery. Jensen AJ; Martinez Molina D; Lundbäck T Future Med Chem; 2015; 7(8):975-8. PubMed ID: 26062395 [No Abstract] [Full Text] [Related]
8. Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout. Al-Amin RA; Gallant CJ; Muthelo PM; Landegren U Anal Chem; 2021 Aug; 93(31):10999-11009. PubMed ID: 34319715 [TBL] [Abstract][Full Text] [Related]
9. Drug Target Engagement Using Coupled Cellular Thermal Shift Assay-Acoustic Reverse-Phase Protein Array. Herledan A; Andres M; Lejeune-Dodge A; Leroux F; Biela A; Piveteau C; Warenghem S; Couturier C; Deprez B; Deprez-Poulain R SLAS Discov; 2020 Feb; 25(2):207-214. PubMed ID: 31885312 [TBL] [Abstract][Full Text] [Related]
10. Target engagement in lead generation. Durham TB; Blanco MJ Bioorg Med Chem Lett; 2015 Mar; 25(5):998-1008. PubMed ID: 25630223 [TBL] [Abstract][Full Text] [Related]
11. In Situ Target Engagement Studies in Adherent Cells. Axelsson H; Almqvist H; Otrocka M; Vallin M; Lundqvist S; Hansson P; Karlsson U; Lundbäck T; Seashore-Ludlow B ACS Chem Biol; 2018 Apr; 13(4):942-950. PubMed ID: 29433316 [TBL] [Abstract][Full Text] [Related]
12. Indirect Detection of Ligand Binding by Thermal Melt Analysis. Shaw J; Stubbs C Methods Mol Biol; 2021; 2263():201-215. PubMed ID: 33877599 [TBL] [Abstract][Full Text] [Related]
13. High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery. Henderson MJ; Holbert MA; Simeonov A; Kallal LA SLAS Discov; 2020 Feb; 25(2):137-147. PubMed ID: 31566060 [TBL] [Abstract][Full Text] [Related]
14. The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies. Martinez Molina D; Nordlund P Annu Rev Pharmacol Toxicol; 2016; 56():141-61. PubMed ID: 26566155 [TBL] [Abstract][Full Text] [Related]