BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 25105836)

  • 1. The Succinated Proteome of FH-Mutant Tumours.
    Yang M; Ternette N; Su H; Dabiri R; Kessler BM; Adam J; Teh BT; Pollard PJ
    Metabolites; 2014 Aug; 4(3):640-54. PubMed ID: 25105836
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
    Bardella C; El-Bahrawy M; Frizzell N; Adam J; Ternette N; Hatipoglu E; Howarth K; O'Flaherty L; Roberts I; Turner G; Taylor J; Giaslakiotis K; Macaulay VM; Harris AL; Chandra A; Lehtonen HJ; Launonen V; Aaltonen LA; Pugh CW; Mihai R; Trudgian D; Kessler B; Baynes JW; Ratcliffe PJ; Tomlinson IP; Pollard PJ
    J Pathol; 2011 Sep; 225(1):4-11. PubMed ID: 21630274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.
    Ternette N; Yang M; Laroyia M; Kitagawa M; O'Flaherty L; Wolhulter K; Igarashi K; Saito K; Kato K; Fischer R; Berquand A; Kessler BM; Lappin T; Frizzell N; Soga T; Adam J; Pollard PJ
    Cell Rep; 2013 Mar; 3(3):689-700. PubMed ID: 23499446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry.
    Chen YB; Brannon AR; Toubaji A; Dudas ME; Won HH; Al-Ahmadie HA; Fine SW; Gopalan A; Frizzell N; Voss MH; Russo P; Berger MF; Tickoo SK; Reuter VE
    Am J Surg Pathol; 2014 May; 38(5):627-37. PubMed ID: 24441663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The succinated proteome.
    Merkley ED; Metz TO; Smith RD; Baynes JW; Frizzell N
    Mass Spectrom Rev; 2014; 33(2):98-109. PubMed ID: 24115015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of protein S-(2-succino)-cysteine (2SC) succination as a biomarker for fumarate hydratase-deficient renal cell carcinoma.
    Mannan R; Wang X; Bawa PS; Chugh S; Chinnaiyan AK; Rangaswamy R; Zhang Y; Cao X; Smith SC; Trpkov K; Williamson SR; Sangoi AR; Mohanty S; McKenney JK; Gupta S; Magi-Galluzzi C; Argani P; Osunkoya AO; Chinnaiyan AM; Dhanasekaran SM; Mehra R
    Hum Pathol; 2023 Apr; 134():102-113. PubMed ID: 36581128
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.
    Llamas-Velasco M; Requena L; Adam J; Frizzell N; Hartmann A; Mentzel T
    Am J Dermatopathol; 2016 Dec; 38(12):887-891. PubMed ID: 27097334
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.
    Joseph NM; Solomon DA; Frizzell N; Rabban JT; Zaloudek C; Garg K
    Am J Surg Pathol; 2015 Nov; 39(11):1529-39. PubMed ID: 26457356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Incidence of succinate dehydrogenase and fumarate hydratase-deficient renal cell carcinoma based on immunohistochemical screening with SDHA/SDHB and FH/2SC.
    Gupta S; Swanson AA; Chen YB; Lopez T; Milosevic D; Kipp BR; Leibovich BC; Thompson RH; Herrera-Hernandez L; Cheville JC; Jimenez RE
    Hum Pathol; 2019 Sep; 91():114-122. PubMed ID: 31299266
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Immunohistochemistry for 2-Succinocysteine (2SC) and Fumarate Hydratase (FH) in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome).
    Buelow B; Cohen J; Nagymanyoki Z; Frizzell N; Joseph NM; McCalmont T; Garg K
    Am J Surg Pathol; 2016 Jul; 40(7):982-8. PubMed ID: 26945337
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.
    Perez M; Bak DW; Bergholtz SE; Crooks DR; Arimilli BS; Yang Y; Weerapana E; Linehan WM; Meier JL
    J Biol Chem; 2020 Sep; 295(39):13410-13418. PubMed ID: 32820045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas.
    Kämpjärvi K; Mäkinen N; Mehine M; Välipakka S; Uimari O; Pitkänen E; Heinonen HR; Heikkinen T; Tolvanen J; Ahtikoski A; Frizzell N; Sarvilinna N; Sjöberg J; Bützow R; Aaltonen LA; Vahteristo P
    Br J Cancer; 2016 Jun; 114(12):1405-11. PubMed ID: 27187686
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Succination of proteins in diabetes.
    Frizzell N; Lima M; Baynes JW
    Free Radic Res; 2011 Jan; 45(1):101-9. PubMed ID: 20964553
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Advances in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) research.
    Ooi A
    Semin Cancer Biol; 2020 Apr; 61():158-166. PubMed ID: 31689495
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Succination of Protein Thiols in Human Brain Aging.
    Jové M; Pradas I; Mota-Martorell N; Cabré R; Ayala V; Ferrer I; Pamplona R
    Front Aging Neurosci; 2020; 12():52. PubMed ID: 32210786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.
    Blatnik M; Frizzell N; Thorpe SR; Baynes JW
    Diabetes; 2008 Jan; 57(1):41-9. PubMed ID: 17934141
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.
    Blatnik M; Thorpe SR; Baynes JW
    Ann N Y Acad Sci; 2008 Apr; 1126():272-5. PubMed ID: 18448829
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.
    Piroli GG; Manuel AM; Clapper AC; Walla MD; Baatz JE; Palmiter RD; Quintana A; Frizzell N
    Mol Cell Proteomics; 2016 Feb; 15(2):445-61. PubMed ID: 26450614
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients.
    Bateman NW; Tarney CM; Abulez T; Soltis AR; Zhou M; Conrads K; Litzi T; Oliver J; Hood B; Driggers P; Viollet C; Dalgard C; Wilkerson M; Catherino W; Hamilton CA; Darcy KM; Casablanca Y; Al-Hendy A; Segars J; Conrads TP; Larry Maxwell G
    Sci Rep; 2021 Apr; 11(1):9371. PubMed ID: 33931688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The emerging role of fumarate as an oncometabolite.
    Yang M; Soga T; Pollard PJ; Adam J
    Front Oncol; 2012; 2():85. PubMed ID: 22866264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.