344 related articles for article (PubMed ID: 25107887)
1. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
[TBL] [Abstract][Full Text] [Related]
2. KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.
Zhou D; Liu K; Sun CW; Pawlik KM; Townes TM
Nat Genet; 2010 Sep; 42(9):742-4. PubMed ID: 20676097
[TBL] [Abstract][Full Text] [Related]
3. Krüppel-Like Transcription Factor KLF1 Is Required for Optimal γ- and β-Globin Expression in Human Fetal Erythroblasts.
Vinjamur DS; Alhashem YN; Mohamad SF; Amin P; Williams DC; Lloyd JA
PLoS One; 2016; 11(2):e0146802. PubMed ID: 26840243
[TBL] [Abstract][Full Text] [Related]
4. Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells.
Amaya M; Desai M; Gnanapragasam MN; Wang SZ; Zu Zhu S; Williams DC; Ginder GD
Blood; 2013 Apr; 121(17):3493-501. PubMed ID: 23444401
[TBL] [Abstract][Full Text] [Related]
5. Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells.
Macari ER; Schaeffer EK; West RJ; Lowrey CH
Blood; 2013 Jan; 121(5):830-9. PubMed ID: 23223429
[TBL] [Abstract][Full Text] [Related]
6. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
7. Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells.
Ochi K; Takayama N; Hirose S; Nakahata T; Nakauchi H; Eto K
Stem Cells Transl Med; 2014 Jul; 3(7):792-800. PubMed ID: 24873860
[TBL] [Abstract][Full Text] [Related]
8. Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.
Esteghamat F; Gillemans N; Bilic I; van den Akker E; Cantù I; van Gent T; Klingmüller U; van Lom K; von Lindern M; Grosveld F; Bryn van Dijk T; Busslinger M; Philipsen S
Blood; 2013 Mar; 121(13):2553-62. PubMed ID: 23361909
[TBL] [Abstract][Full Text] [Related]
9. Flicking the switch: adult hemoglobin expression in erythroid cells derived from cord blood and human induced pluripotent stem cells.
Cantú I; Philipsen S
Haematologica; 2014 Nov; 99(11):1647-9. PubMed ID: 25420279
[No Abstract] [Full Text] [Related]
10. MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.
Lulli V; Romania P; Morsilli O; Cianciulli P; Gabbianelli M; Testa U; Giuliani A; Marziali G
PLoS One; 2013; 8(4):e60436. PubMed ID: 23593217
[TBL] [Abstract][Full Text] [Related]
11. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
12. Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny.
Chang KH; Huang A; Han H; Jiang Y; Fang X; Song CZ; Padilla S; Wang H; Qu H; Stamatoyannopoulos J; Li Q; Papayannopoulou T
Exp Hematol; 2013 Nov; 41(11):967-979.e6. PubMed ID: 23993951
[TBL] [Abstract][Full Text] [Related]
13. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
14. Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
Dulmovits BM; Appiah-Kubi AO; Papoin J; Hale J; He M; Al-Abed Y; Didier S; Gould M; Husain-Krautter S; Singh SA; Chan KW; Vlachos A; Allen SL; Taylor N; Marambaud P; An X; Gallagher PG; Mohandas N; Lipton JM; Liu JM; Blanc L
Blood; 2016 Mar; 127(11):1481-92. PubMed ID: 26679864
[TBL] [Abstract][Full Text] [Related]
15. Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B.
Papadopoulos P; Kafasi A; De Cuyper IM; Barroca V; Lewandowski D; Kadri Z; Veldthuis M; Berghuis J; Gillemans N; Benavente Cuesta CM; Grosveld FG; van Zwieten R; Philipsen S; Vernet M; Gutiérrez L; Patrinos GP
Hum Genomics; 2020 Oct; 14(1):39. PubMed ID: 33066815
[TBL] [Abstract][Full Text] [Related]
16. POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.
Gudmundsdottir B; Gudmundsson KO; Klarmann KD; Singh SK; Sun L; Singh S; Du Y; Coppola V; Stockwin L; Nguyen N; Tessarollo L; Thorsteinsson L; Sigurjonsson OE; Gudmundsson S; Rafnar T; Tisdale JF; Keller JR
Cell Rep; 2018 Jun; 23(11):3236-3248. PubMed ID: 29898395
[TBL] [Abstract][Full Text] [Related]
17. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
18. Genetic disruption of the KLF1 gene to overexpress the γ-globin gene using the CRISPR/Cas9 system.
Shariati L; Khanahmad H; Salehi M; Hejazi Z; Rahimmanesh I; Tabatabaiefar MA; Modarressi MH
J Gene Med; 2016 Oct; 18(10):294-301. PubMed ID: 27668420
[TBL] [Abstract][Full Text] [Related]
19. A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo.
McGrath KE; Frame JM; Fromm GJ; Koniski AD; Kingsley PD; Little J; Bulger M; Palis J
Blood; 2011 Apr; 117(17):4600-8. PubMed ID: 21378272
[TBL] [Abstract][Full Text] [Related]
20. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Rajendiran V; Devaraju N; Haddad M; Ravi NS; Panigrahi L; Paul J; Gopalakrishnan C; Wyman S; Ariudainambi K; Mahalingam G; Periyasami Y; Prasad K; George A; Sukumaran D; Gopinathan S; Pai AA; Nakamura Y; Balasubramanian P; Ramalingam R; Thangavel S; Velayudhan SR; Corn JE; Mackay JP; Marepally S; Srivastava A; Crossley M; Mohankumar KM
Mol Ther; 2024 Mar; 32(3):663-677. PubMed ID: 38273654
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
