BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 25109331)

  • 1. Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity.
    Riemer P; Sreekumar A; Reinke S; Rad R; Schäfer R; Sers C; Bläker H; Herrmann BG; Morkel M
    Oncogene; 2015 Jun; 34(24):3164-75. PubMed ID: 25109331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
    Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
    Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
    Buchert M; Rohde F; Eissmann M; Tebbutt N; Williams B; Tan CW; Owen A; Hirokawa Y; Gnann A; Orend G; Orner G; Dashwood RH; Heath JK; Ernst M; Janssen KP
    Dis Model Mech; 2015 Nov; 8(11):1361-73. PubMed ID: 26398937
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.
    Nik AM; Reyahi A; Pontén F; Carlsson P
    Gastroenterology; 2013 May; 144(5):1001-11. PubMed ID: 23376422
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.
    Lee G; Goretsky T; Managlia E; Dirisina R; Singh AP; Brown JB; May R; Yang GY; Ragheb JW; Evers BM; Weber CR; Turner JR; He XC; Katzman RB; Li L; Barrett TA
    Gastroenterology; 2010 Sep; 139(3):869-81, 881.e1-9. PubMed ID: 20580720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diminished WNT -> β-catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumors.
    Juan J; Muraguchi T; Iezza G; Sears RC; McMahon M
    Genes Dev; 2014 Mar; 28(6):561-75. PubMed ID: 24589553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wnt and BMP signals control intestinal adenoma cell fates.
    Farrall AL; Riemer P; Leushacke M; Sreekumar A; Grimm C; Herrmann BG; Morkel M
    Int J Cancer; 2012 Nov; 131(10):2242-52. PubMed ID: 22344573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.
    Lemieux E; Cagnol S; Beaudry K; Carrier J; Rivard N
    Oncogene; 2015 Sep; 34(38):4914-27. PubMed ID: 25500543
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.
    Leach JDG; Vlahov N; Tsantoulis P; Ridgway RA; Flanagan DJ; Gilroy K; Sphyris N; Vázquez EG; Vincent DF; Faller WJ; Hodder MC; Raven A; Fey S; Najumudeen AK; Strathdee D; Nixon C; Hughes M; Clark W; Shaw R; ; van Hooff SR; Huels DJ; Medema JP; Barry ST; Frame MC; Unciti-Broceta A; Leedham SJ; Inman GJ; Jackstadt R; Thompson BJ; Campbell AD; Tejpar S; Sansom OJ
    Nat Commun; 2021 Jun; 12(1):3464. PubMed ID: 34103493
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
    Brandt R; Sell T; Lüthen M; Uhlitz F; Klinger B; Riemer P; Giesecke-Thiel C; Schulze S; El-Shimy IA; Kunkel D; Fauler B; Mielke T; Mages N; Herrmann BG; Sers C; Blüthgen N; Morkel M
    Nat Commun; 2019 Jul; 10(1):2919. PubMed ID: 31266962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after γ-irradiation through Wnt/β-catenin pathway.
    Sakamaki A; Katsuragi Y; Otsuka K; Tomita M; Obata M; Iwasaki T; Abe M; Sato T; Ochiai M; Sakuraba Y; Aoyagi Y; Gondo Y; Sakimura K; Nakagama H; Mishima Y; Kominami R
    Carcinogenesis; 2015 Jun; 36(6):622-31. PubMed ID: 25827435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wnt signaling suppresses MAPK-driven proliferation of intestinal stem cells.
    Kabiri Z; Greicius G; Zaribafzadeh H; Hemmerich A; Counter CM; Virshup DM
    J Clin Invest; 2018 Aug; 128(9):3806-3812. PubMed ID: 30059017
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alcohol Injury Damages Intestinal Stem Cells.
    Lu R; Voigt RM; Zhang Y; Kato I; Xia Y; Forsyth CB; Keshavarzian A; Sun J
    Alcohol Clin Exp Res; 2017 Apr; 41(4):727-734. PubMed ID: 28195397
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity.
    Janeckova L; Fafilek B; Krausova M; Horazna M; Vojtechova M; Alberich-Jorda M; Sloncova E; Galuskova K; Sedlacek R; Anderova M; Korinek V
    Genesis; 2016 Mar; 54(3):101-14. PubMed ID: 26864984
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.
    Bond CE; Liu C; Kawamata F; McKeone DM; Fernando W; Jamieson S; Pearson SA; Kane A; Woods SL; Lannagan TRM; Somashekar R; Lee Y; Dumenil T; Hartel G; Spring KJ; Borowsky J; Fennell L; Bettington M; Lee J; Worthley DL; Leggett BA; Whitehall VLJ
    Epigenetics; 2018; 13(1):40-48. PubMed ID: 29235923
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch.
    López-Arribillaga E; Rodilla V; Pellegrinet L; Guiu J; Iglesias M; Roman AC; Gutarra S; González S; Muñoz-Cánoves P; Fernández-Salguero P; Radtke F; Bigas A; Espinosa L
    Development; 2015 Jan; 142(1):41-50. PubMed ID: 25480918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.
    Tong K; Pellón-Cárdenas O; Sirihorachai VR; Warder BN; Kothari OA; Perekatt AO; Fokas EE; Fullem RL; Zhou A; Thackray JK; Tran H; Zhang L; Xing J; Verzi MP
    Cell Rep; 2017 Dec; 21(13):3833-3845. PubMed ID: 29281831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Olfactomedin 4 deletion induces colon adenocarcinoma in Apc
    Liu W; Li H; Hong SH; Piszczek GP; Chen W; Rodgers GP
    Oncogene; 2016 Oct; 35(40):5237-5247. PubMed ID: 26973250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
    Janssen KP; Alberici P; Fsihi H; Gaspar C; Breukel C; Franken P; Rosty C; Abal M; El Marjou F; Smits R; Louvard D; Fodde R; Robine S
    Gastroenterology; 2006 Oct; 131(4):1096-109. PubMed ID: 17030180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis.
    Fang L; Zhu Q; Neuenschwander M; Specker E; Wulf-Goldenberg A; Weis WI; von Kries JP; Birchmeier W
    Cancer Res; 2016 Feb; 76(4):891-901. PubMed ID: 26645562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.