132 related articles for article (PubMed ID: 25109950)
1. Anticipating mechanisms of resistance to PI3K inhibition in breast cancer: a challenge in the era of precision medicine.
Leroy C; Amante RJ; Bentires-Alj M
Biochem Soc Trans; 2014 Aug; 42(4):733-41. PubMed ID: 25109950
[TBL] [Abstract][Full Text] [Related]
2. Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer.
Baselga J
Oncologist; 2011; 16 Suppl 1():12-9. PubMed ID: 21278436
[TBL] [Abstract][Full Text] [Related]
3. Approaches and limitations of phosphatidylinositol-3-kinase pathway activation status as a predictive biomarker in the clinical development of targeted therapy.
Coughlin CM; Johnston DS; Strahs A; Burczynski ME; Bacus S; Hill J; Feingold JM; Zacharchuk C; Berkenblit A
Breast Cancer Res Treat; 2010 Nov; 124(1):1-11. PubMed ID: 20803067
[TBL] [Abstract][Full Text] [Related]
4. Evolving strategies for overcoming resistance to HER2-directed therapy: targeting the PI3K/Akt/mTOR pathway.
Nahta R; O'Regan RM
Clin Breast Cancer; 2010 Nov; 10 Suppl 3():S72-8. PubMed ID: 21115425
[TBL] [Abstract][Full Text] [Related]
5. Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?
Zardavas D; Fumagalli D; Loi S
Curr Opin Oncol; 2012 Nov; 24(6):623-34. PubMed ID: 22960556
[TBL] [Abstract][Full Text] [Related]
6. mTOR inhibition in breast cancer: unraveling the complex mechanisms of mTOR signal transduction and its clinical implications in therapy.
O'Regan R; Hawk NN
Expert Opin Ther Targets; 2011 Jul; 15(7):859-72. PubMed ID: 21476875
[TBL] [Abstract][Full Text] [Related]
7. NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.
Serra V; Markman B; Scaltriti M; Eichhorn PJ; Valero V; Guzman M; Botero ML; Llonch E; Atzori F; Di Cosimo S; Maira M; Garcia-Echeverria C; Parra JL; Arribas J; Baselga J
Cancer Res; 2008 Oct; 68(19):8022-30. PubMed ID: 18829560
[TBL] [Abstract][Full Text] [Related]
8. PI3K-Akt pathway: its functions and alterations in human cancer.
Osaki M; Oshimura M; Ito H
Apoptosis; 2004 Nov; 9(6):667-76. PubMed ID: 15505410
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.
McCubrey JA; Steelman LS; Kempf CR; Chappell WH; Abrams SL; Stivala F; Malaponte G; Nicoletti F; Libra M; Bäsecke J; Maksimovic-Ivanic D; Mijatovic S; Montalto G; Cervello M; Cocco L; Martelli AM
J Cell Physiol; 2011 Nov; 226(11):2762-81. PubMed ID: 21302297
[TBL] [Abstract][Full Text] [Related]
10. Targeting phosphoinositide 3-kinase signalling in lung cancer.
Wojtalla A; Arcaro A
Crit Rev Oncol Hematol; 2011 Nov; 80(2):278-90. PubMed ID: 21316260
[TBL] [Abstract][Full Text] [Related]
11. Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer.
Saini KS; Loi S; de Azambuja E; Metzger-Filho O; Saini ML; Ignatiadis M; Dancey JE; Piccart-Gebhart MJ
Cancer Treat Rev; 2013 Dec; 39(8):935-46. PubMed ID: 23643661
[TBL] [Abstract][Full Text] [Related]
12. [Antihormonal therapy in breast cancer and mTOR inhibitors].
Heudel PÉ; Tredan O; Ray-Coquard I; Treilleux I; Guastalla JP; Bachelot T
Bull Cancer; 2011 Dec; 98(12):1431-7. PubMed ID: 22133994
[TBL] [Abstract][Full Text] [Related]
13. The role of the phosphatidylinositol 3-kinase (PI3K) pathway in the development and treatment of uterine cancer.
Naumann RW
Gynecol Oncol; 2011 Nov; 123(2):411-20. PubMed ID: 21903247
[TBL] [Abstract][Full Text] [Related]
14. Efficacy of PI3K inhibitors in advanced breast cancer.
Verret B; Cortes J; Bachelot T; Andre F; Arnedos M
Ann Oncol; 2019 Dec; 30 Suppl 10():x12-x20. PubMed ID: 31928690
[TBL] [Abstract][Full Text] [Related]
15. HER2 expression and PI3K-Akt pathway alterations in gastric cancer.
Sukawa Y; Yamamoto H; Nosho K; Ito M; Igarashi H; Naito T; Mitsuhashi K; Matsunaga Y; Takahashi T; Mikami M; Adachi Y; Suzuki H; Shinomura Y
Digestion; 2014; 89(1):12-7. PubMed ID: 24458107
[TBL] [Abstract][Full Text] [Related]
16. Targeting PI3K signaling as a therapeutic approach for colorectal cancer.
Zhang J; Roberts TM; Shivdasani RA
Gastroenterology; 2011 Jul; 141(1):50-61. PubMed ID: 21723986
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the PI3K pathway: hope we can believe in?
van der Heijden MS; Bernards R
Clin Cancer Res; 2010 Jun; 16(12):3094-9. PubMed ID: 20400520
[TBL] [Abstract][Full Text] [Related]
18. Phosphatidylinositol 3-kinase inhibitors: promising drug candidates for cancer therapy.
Kong D; Yamori T
Cancer Sci; 2008 Sep; 99(9):1734-40. PubMed ID: 18616528
[TBL] [Abstract][Full Text] [Related]
19. Emerging strategies for targeting PI3K in gynecologic cancer.
Bregar AJ; Growdon WB
Gynecol Oncol; 2016 Feb; 140(2):333-44. PubMed ID: 26432040
[TBL] [Abstract][Full Text] [Related]
20. PI3K inhibition to overcome endocrine resistance in breast cancer.
Keegan NM; Gleeson JP; Hennessy BT; Morris PG
Expert Opin Investig Drugs; 2018 Jan; 27(1):1-15. PubMed ID: 29252036
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]