240 related articles for article (PubMed ID: 25112975)
1. Epigenetic promoter silencing in Friedreich ataxia is dependent on repeat length.
Chutake YK; Lam C; Costello WN; Anderson M; Bidichandani SI
Ann Neurol; 2014 Oct; 76(4):522-8. PubMed ID: 25112975
[TBL] [Abstract][Full Text] [Related]
2. Altered nucleosome positioning at the transcription start site and deficient transcriptional initiation in Friedreich ataxia.
Chutake YK; Costello WN; Lam C; Bidichandani SI
J Biol Chem; 2014 May; 289(22):15194-202. PubMed ID: 24737321
[TBL] [Abstract][Full Text] [Related]
3. FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.
Chutake YK; Costello WN; Lam CC; Parikh AC; Hughes TT; Michalopulos MG; Pook MA; Bidichandani SI
PLoS One; 2015; 10(9):e0138437. PubMed ID: 26393353
[TBL] [Abstract][Full Text] [Related]
4. Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor.
Chutake YK; Lam CC; Costello WN; Anderson MP; Bidichandani SI
Nucleic Acids Res; 2016 Jun; 44(11):5095-104. PubMed ID: 26896803
[TBL] [Abstract][Full Text] [Related]
5. The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model.
Clark RM; De Biase I; Malykhina AP; Al-Mahdawi S; Pook M; Bidichandani SI
Hum Genet; 2007 Jan; 120(5):633-40. PubMed ID: 17024371
[TBL] [Abstract][Full Text] [Related]
6. Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia.
Rodden LN; Chutake YK; Gilliam K; Lam C; Soragni E; Hauser L; Gilliam M; Wiley G; Anderson MP; Gottesfeld JM; Lynch DR; Bidichandani SI
Hum Mol Genet; 2021 Feb; 29(23):3818-3829. PubMed ID: 33432325
[TBL] [Abstract][Full Text] [Related]
7. The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions.
Sharma R; Bhatti S; Gomez M; Clark RM; Murray C; Ashizawa T; Bidichandani SI
Hum Mol Genet; 2002 Sep; 11(18):2175-87. PubMed ID: 12189170
[TBL] [Abstract][Full Text] [Related]
8. The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues.
Al-Mahdawi S; Pinto RM; Ismail O; Varshney D; Lymperi S; Sandi C; Trabzuni D; Pook M
Hum Mol Genet; 2008 Mar; 17(5):735-46. PubMed ID: 18045775
[TBL] [Abstract][Full Text] [Related]
9. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.
Lufino MM; Silva AM; Németh AH; Alegre-Abarrategui J; Russell AJ; Wade-Martins R
Hum Mol Genet; 2013 Dec; 22(25):5173-87. PubMed ID: 23943791
[TBL] [Abstract][Full Text] [Related]
10. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming.
Polak U; Li Y; Butler JS; Napierala M
Stem Cells Dev; 2016 Dec; 25(23):1788-1800. PubMed ID: 27615158
[TBL] [Abstract][Full Text] [Related]
11. Compound heterozygosity for an expanded (GAA) and a (GAAGGA) repeat at FXN locus: from a diagnostic pitfall to potential clues to the pathogenesis of Friedreich ataxia.
Santoro M; Perna A; La Rosa P; Petrillo S; Piemonte F; Rossi S; Riso V; Nicoletti TF; Modoni A; Pomponi MG; Chiurazzi P; Silvestri G
Neurogenetics; 2020 Oct; 21(4):279-287. PubMed ID: 32638185
[TBL] [Abstract][Full Text] [Related]
12. Missense mutations linked to friedreich ataxia have different but synergistic effects on mitochondrial frataxin isoforms.
Li H; Gakh O; Smith DY; Ranatunga WK; Isaya G
J Biol Chem; 2013 Feb; 288(6):4116-27. PubMed ID: 23269675
[TBL] [Abstract][Full Text] [Related]
13. Complete FXN deletion in a patient with Friedreich's ataxia.
van den Ouweland AM; van Minkelen R; Bolman GM; Wouters CH; Becht-Noordermeer C; Deelen WH; Deelen-Manders JM; Ippel EP; Saris J; Halley DJ
Genet Test Mol Biomarkers; 2012 Sep; 16(9):1015-8. PubMed ID: 22691228
[TBL] [Abstract][Full Text] [Related]
14. Progressive GAA expansions in dorsal root ganglia of Friedreich's ataxia patients.
De Biase I; Rasmussen A; Endres D; Al-Mahdawi S; Monticelli A; Cocozza S; Pook M; Bidichandani SI
Ann Neurol; 2007 Jan; 61(1):55-60. PubMed ID: 17262846
[TBL] [Abstract][Full Text] [Related]
15. Epigenetic silencing in Friedreich ataxia is associated with depletion of CTCF (CCCTC-binding factor) and antisense transcription.
De Biase I; Chutake YK; Rindler PM; Bidichandani SI
PLoS One; 2009 Nov; 4(11):e7914. PubMed ID: 19956589
[TBL] [Abstract][Full Text] [Related]
16. DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.
Rodden LN; Gilliam KM; Lam C; Rojsajjakul T; Mesaros C; Dionisi C; Pook M; Pandolfo M; Lynch DR; Blair IA; Bidichandani SI
Sci Rep; 2022 Mar; 12(1):5031. PubMed ID: 35322126
[TBL] [Abstract][Full Text] [Related]
17. Exonic deletions of FXN and early-onset Friedreich ataxia.
Anheim M; Mariani LL; Calvas P; Cheuret E; Zagnoli F; Odent S; Seguela C; Marelli C; Fritsch M; Delaunoy JP; Brice A; Dürr A; Koenig M
Arch Neurol; 2012 Jul; 69(7):912-6. PubMed ID: 22409940
[TBL] [Abstract][Full Text] [Related]
18. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.
Du J; Campau E; Soragni E; Ku S; Puckett JW; Dervan PB; Gottesfeld JM
J Biol Chem; 2012 Aug; 287(35):29861-72. PubMed ID: 22798143
[TBL] [Abstract][Full Text] [Related]
19. FXN methylation predicts expression and clinical outcome in Friedreich ataxia.
Evans-Galea MV; Carrodus N; Rowley SM; Corben LA; Tai G; Saffery R; Galati JC; Wong NC; Craig JM; Lynch DR; Regner SR; Brocht AF; Perlman SL; Bushara KO; Gomez CM; Wilmot GR; Li L; Varley E; Delatycki MB; Sarsero JP
Ann Neurol; 2012 Apr; 71(4):487-97. PubMed ID: 22522441
[TBL] [Abstract][Full Text] [Related]
20. Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia.
Kim E; Napierala M; Dent SY
Nucleic Acids Res; 2011 Oct; 39(19):8366-77. PubMed ID: 21745819
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
