BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 25114223)

  • 1. Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.
    Sundberg TB; Choi HG; Song JH; Russell CN; Hussain MM; Graham DB; Khor B; Gagnon J; O'Connell DJ; Narayan K; Dančík V; Perez JR; Reinecker HC; Gray NS; Schreiber SL; Xavier RJ; Shamji AF
    Proc Natl Acad Sci U S A; 2014 Aug; 111(34):12468-73. PubMed ID: 25114223
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.
    Ozanne J; Prescott AR; Clark K
    Biochem J; 2015 Jan; 465(2):271-9. PubMed ID: 25351958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype.
    Lombardi MS; Gilliéron C; Dietrich D; Gabay C
    J Leukoc Biol; 2016 May; 99(5):711-21. PubMed ID: 26590148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HG-9-91-01 Attenuates Murine Experimental Colitis by Promoting Interleukin-10 Production in Colonic Macrophages Through the SIK/CRTC3 Pathway.
    Fu Y; Ma G; Zhang Y; Wang W; Shi T; Zhu J; Zhang J; Huang Z; Chen J
    Inflamm Bowel Dis; 2021 Oct; 27(11):1821-1831. PubMed ID: 33988718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis.
    Wölfl M; Schwinn S; Yoo YE; Reß ML; Braun M; Chopra M; Schreiber SC; Ayala VI; Ohlen C; Eyrich M; Beilhack A; Schlegel PG
    Blood; 2013 Aug; 122(7):1203-13. PubMed ID: 23836556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages.
    Clark K; MacKenzie KF; Petkevicius K; Kristariyanto Y; Zhang J; Choi HG; Peggie M; Plater L; Pedrioli PG; McIver E; Gray NS; Arthur JS; Cohen P
    Proc Natl Acad Sci U S A; 2012 Oct; 109(42):16986-91. PubMed ID: 23033494
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells.
    Remsing Rix LL; Rix U; Colinge J; Hantschel O; Bennett KL; Stranzl T; Müller A; Baumgartner C; Valent P; Augustin M; Till JH; Superti-Furga G
    Leukemia; 2009 Mar; 23(3):477-85. PubMed ID: 19039322
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bosutinib Attenuates Inflammation via Inhibiting Salt-Inducible Kinases in Experimental Model of Intracerebral Hemorrhage on Mice.
    Ma L; Manaenko A; Ou YB; Shao AW; Yang SX; Zhang JH
    Stroke; 2017 Nov; 48(11):3108-3116. PubMed ID: 29018127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
    Darling NJ; Toth R; Arthur JS; Clark K
    Biochem J; 2017 Feb; 474(4):521-537. PubMed ID: 27920213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells.
    Hirata N; Yanagawa Y; Ebihara T; Seya T; Uematsu S; Akira S; Hayashi F; Iwabuchi K; Onoé K
    Mol Immunol; 2008 May; 45(10):2734-42. PubMed ID: 18372043
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imperatorin exerts antiallergic effects in Th2-mediated allergic asthma via induction of IL-10-producing regulatory T cells by modulating the function of dendritic cells.
    Lin CL; Hsiao G; Wang CC; Lee YL
    Pharmacol Res; 2016 Aug; 110():111-121. PubMed ID: 27185659
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tyrosine kinase inhibitor dasatinib suppresses cytokine production by plasmacytoid dendritic cells by targeting endosomal transport of CpG DNA.
    Fujita H; Kitawaki T; Sato T; Maeda T; Kamihira S; Takaori-Kondo A; Kadowaki N
    Eur J Immunol; 2013 Jan; 43(1):93-103. PubMed ID: 23112129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis.
    Lombardi MS; Gilliéron C; Berkelaar M; Gabay C
    PLoS One; 2017; 12(10):e0185426. PubMed ID: 28973003
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment.
    Liang W; Kujawski M; Wu J; Lu J; Herrmann A; Loera S; Yen Y; Lee F; Yu H; Wen W; Jove R
    Clin Cancer Res; 2010 Feb; 16(3):924-35. PubMed ID: 20103658
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells.
    Kwon HK; Hwang JS; Lee CG; So JS; Sahoo A; Im CR; Jeon WK; Ko BS; Lee SH; Park ZY; Im SH
    World J Gastroenterol; 2011 Feb; 17(8):976-86. PubMed ID: 21451725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS.
    Turnquist HR; Cardinal J; Macedo C; Rosborough BR; Sumpter TL; Geller DA; Metes D; Thomson AW
    Blood; 2010 Jun; 115(23):4758-69. PubMed ID: 20335217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of tumor necrosis factor-α for interleukin-10 production by murine dendritic cells.
    Hirata N; Yanagawa Y; Ogura H; Satoh M; Noguchi M; Matsumoto M; Togashi H; Onoé K; Iwabuchi K
    Cell Immunol; 2011; 266(2):165-71. PubMed ID: 20979991
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).
    Wermuth PJ; Jimenez SA
    PLoS One; 2018; 13(5):e0196559. PubMed ID: 29718973
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.
    Dhawan G; Combs CK
    J Neuroinflammation; 2012 Jul; 9():117. PubMed ID: 22673542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo.
    Fraser CK; Lousberg EL; Kumar R; Hughes TP; Diener KR; Hayball JD
    Exp Hematol; 2009 Dec; 37(12):1435-44. PubMed ID: 19786067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.