BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 25116336)

  • 1. Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase.
    Yan W; Jung YS; Zhang Y; Chen X
    PLoS One; 2014; 9(8):e103497. PubMed ID: 25116336
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein.
    Yan W; Chen X; Zhang Y; Zhang J; Jung YS; Chen X
    J Biol Chem; 2013 Feb; 288(5):2907-13. PubMed ID: 23271742
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation.
    Jung YS; Qian Y; Chen X
    J Biol Chem; 2011 Oct; 286(41):35388-35395. PubMed ID: 21852228
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression.
    Yan W; Zhang Y; Zhang J; Liu S; Cho SJ; Chen X
    J Biol Chem; 2011 May; 286(20):17478-86. PubMed ID: 21454520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.
    Jung YS; Liu G; Chen X
    Mol Cell Biol; 2010 Feb; 30(4):1041-8. PubMed ID: 20008555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome inhibitors suppress the protein expression of mutant p53.
    Halasi M; Pandit B; Gartel AL
    Cell Cycle; 2014; 13(20):3202-6. PubMed ID: 25485499
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53.
    Zheng G; Ning J; Yang YC
    Biochem Biophys Res Commun; 2007 Dec; 364(2):344-50. PubMed ID: 17950244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.
    Li D; Marchenko ND; Moll UM
    Cell Death Differ; 2011 Dec; 18(12):1904-13. PubMed ID: 21637290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63.
    Jung YS; Qian Y; Yan W; Chen X
    J Invest Dermatol; 2013 May; 133(5):1178-87. PubMed ID: 23235527
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1.
    Bergiers I; Bridoux L; Nguyen N; Twizere JC; Rezsöhazy R
    PLoS One; 2013; 8(11):e80387. PubMed ID: 24244684
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms.
    Maroui MA; Kheddache-Atmane S; El Asmi F; Dianoux L; Aubry M; Chelbi-Alix MK
    PLoS One; 2012; 7(9):e44949. PubMed ID: 23028697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
    J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HIV-1 Nef promotes ubiquitination and proteasomal degradation of p53 tumor suppressor protein by using E6AP.
    Ali A; Farooqui SR; Rai J; Singh J; Kumar V; Mishra R; Banerjea AC
    Biochem Biophys Res Commun; 2020 Sep; 529(4):1038-1044. PubMed ID: 32819562
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation.
    Li Y; Qu X; Qu J; Zhang Y; Liu J; Teng Y; Hu X; Hou K; Liu Y
    Cancer Lett; 2009 Nov; 284(2):208-15. PubMed ID: 19457607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [TUMOR SUPPRESSOR p63 REGULATES EXPRESSION OF UBIQUITIN LIGASE Pirh2].
    Daks AA; Petukhov AV; Shuvalov OY; Vasilieva EA; Melino G; Barlev NA; Fedorova OA
    Tsitologiia; 2015; 57(12):876-9. PubMed ID: 26995965
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.
    Momeny M; Zakidizaji M; Ghasemi R; Dehpour AR; Rahimi-Balaei M; Abdolazimi Y; Ghavamzadeh A; Alimoghaddam K; Ghaffari SH
    Med Oncol; 2010 Sep; 27(3):833-42. PubMed ID: 19763917
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination.
    Wu H; Zeinab RA; Flores ER; Leng RP
    Mol Cancer Res; 2011 Dec; 9(12):1780-90. PubMed ID: 21994467
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNF125 is a ubiquitin-protein ligase that promotes p53 degradation.
    Yang L; Zhou B; Li X; Lu Z; Li W; Huo X; Miao Z
    Cell Physiol Biochem; 2015; 35(1):237-45. PubMed ID: 25591766
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells.
    Jo S; Lee YL; Kim S; Lee H; Chung H
    Biochim Biophys Acta; 2016 Jul; 1863(7 Pt A):1499-509. PubMed ID: 27030546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT.
    Yang-Hartwich Y; Tedja R; Roberts CM; Goodner-Bingham J; Cardenas C; Gurea M; Sumi NJ; Alvero AB; Glackin CA; Mor G
    Mol Cancer Res; 2019 Jan; 17(1):153-164. PubMed ID: 30131448
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.