188 related articles for article (PubMed ID: 25120187)
21. Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2).
Flagg SC; Giri N; Pektas S; Maroney MJ; Knapp MJ
Biochemistry; 2012 Aug; 51(33):6654-66. PubMed ID: 22747465
[TBL] [Abstract][Full Text] [Related]
22. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
23. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
Strowitzki MJ; Cummins EP; Taylor CT
Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
[TBL] [Abstract][Full Text] [Related]
24. Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
Ehrismann D; Flashman E; Genn DN; Mathioudakis N; Hewitson KS; Ratcliffe PJ; Schofield CJ
Biochem J; 2007 Jan; 401(1):227-34. PubMed ID: 16952279
[TBL] [Abstract][Full Text] [Related]
25. Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1).
Chowdhury R; Flashman E; Mecinović J; Kramer HB; Kessler BM; Frapart YM; Boucher JL; Clifton IJ; McDonough MA; Schofield CJ
J Mol Biol; 2011 Jul; 410(2):268-79. PubMed ID: 21601578
[TBL] [Abstract][Full Text] [Related]
26. The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.
Arsenault PR; Song D; Chung YJ; Khurana TS; Lee FS
Mol Cell Biol; 2016 Sep; 36(18):2328-43. PubMed ID: 27325674
[TBL] [Abstract][Full Text] [Related]
27. Development of a colorimetric α-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins.
Wong SJ; Ringel AE; Yuan W; Paulo JA; Yoon H; Currie MA; Haigis MC
J Biol Chem; 2021; 296():100397. PubMed ID: 33571527
[TBL] [Abstract][Full Text] [Related]
28. Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology.
Dao JH; Kurzeja RJ; Morachis JM; Veith H; Lewis J; Yu V; Tegley CM; Tagari P
Anal Biochem; 2009 Jan; 384(2):213-23. PubMed ID: 18952043
[TBL] [Abstract][Full Text] [Related]
29. Selective inhibition of the hypoxia-inducible factor prolyl hydroxylase PHD3 by Zn(II).
Na YR; Woo DJ; Choo H; Chung HS; Yang EG
Chem Commun (Camb); 2015 Jul; 51(53):10730-3. PubMed ID: 26051901
[TBL] [Abstract][Full Text] [Related]
30. Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2.
Hou P; Kuo CY; Cheng CT; Liou JP; Ann DK; Chen Q
PLoS One; 2014; 9(11):e113865. PubMed ID: 25420025
[TBL] [Abstract][Full Text] [Related]
31. Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate.
Grzyska PK; Ryle MJ; Monterosso GR; Liu J; Ballou DP; Hausinger RP
Biochemistry; 2005 Mar; 44(10):3845-55. PubMed ID: 15751960
[TBL] [Abstract][Full Text] [Related]
32. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
[TBL] [Abstract][Full Text] [Related]
33. Biochemistry of the hypoxia-inducible factor hydroxylases.
Fiorini G; Schofield CJ
Curr Opin Chem Biol; 2024 Apr; 79():102428. PubMed ID: 38330792
[TBL] [Abstract][Full Text] [Related]
34. Kinetic Analysis of HIF Prolyl Hydroxylases.
Koivunen P; Myllyharju J
Methods Mol Biol; 2018; 1742():15-25. PubMed ID: 29330786
[TBL] [Abstract][Full Text] [Related]
35. Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Chowdhury R; Leung IK; Tian YM; Abboud MI; Ge W; Domene C; Cantrelle FX; Landrieu I; Hardy AP; Pugh CW; Ratcliffe PJ; Claridge TD; Schofield CJ
Nat Commun; 2016 Aug; 7():12673. PubMed ID: 27561929
[TBL] [Abstract][Full Text] [Related]
36. Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases.
Chan MC; Ilott NE; Schödel J; Sims D; Tumber A; Lippl K; Mole DR; Pugh CW; Ratcliffe PJ; Ponting CP; Schofield CJ
J Biol Chem; 2016 Sep; 291(39):20661-73. PubMed ID: 27502280
[TBL] [Abstract][Full Text] [Related]
37. Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH).
Hewitson KS; Holmes SL; Ehrismann D; Hardy AP; Chowdhury R; Schofield CJ; McDonough MA
J Biol Chem; 2008 Sep; 283(38):25971-8. PubMed ID: 18611856
[TBL] [Abstract][Full Text] [Related]
38. Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.
Flashman E; Bagg EA; Chowdhury R; Mecinović J; Loenarz C; McDonough MA; Hewitson KS; Schofield CJ
J Biol Chem; 2008 Feb; 283(7):3808-15. PubMed ID: 18063574
[TBL] [Abstract][Full Text] [Related]
39. Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate.
McNeill LA; Flashman E; Buck MR; Hewitson KS; Clifton IJ; Jeschke G; Claridge TD; Ehrismann D; Oldham NJ; Schofield CJ
Mol Biosyst; 2005 Oct; 1(4):321-4. PubMed ID: 16880998
[TBL] [Abstract][Full Text] [Related]
40. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]