238 related articles for article (PubMed ID: 25122770)
1. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism.
Alvarado JJ; Betts L; Moroco JA; Smithgall TE; Yeh JI
J Biol Chem; 2010 Nov; 285(46):35455-61. PubMed ID: 20810664
[TBL] [Abstract][Full Text] [Related]
3. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.
Moroco JA; Alvarado JJ; Staudt RP; Shi H; Wales TE; Smithgall TE; Engen JR
J Mol Biol; 2018 Feb; 430(3):310-321. PubMed ID: 29258818
[TBL] [Abstract][Full Text] [Related]
4. Activation of the Src family kinase Hck without SH3-linker release.
Lerner EC; Trible RP; Schiavone AP; Hochrein JM; Engen JR; Smithgall TE
J Biol Chem; 2005 Dec; 280(49):40832-7. PubMed ID: 16210316
[TBL] [Abstract][Full Text] [Related]
5. Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.
Jung J; Byeon IJ; Ahn J; Gronenborn AM
Proteins; 2011 May; 79(5):1609-22. PubMed ID: 21365684
[TBL] [Abstract][Full Text] [Related]
6. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
Dutartre H; Harris M; Olive D; Collette Y
Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
[TBL] [Abstract][Full Text] [Related]
7. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT
Nature; 1997 Feb; 385(6617):650-3. PubMed ID: 9024665
[TBL] [Abstract][Full Text] [Related]
8. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
Briggs SD; Sharkey M; Stevenson M; Smithgall TE
J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
[TBL] [Abstract][Full Text] [Related]
9. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
Wales TE; Hochrein JM; Morgan CR; Emert-Sedlak LA; Smithgall TE; Engen JR
Biochemistry; 2015 Oct; 54(41):6382-91. PubMed ID: 26440750
[TBL] [Abstract][Full Text] [Related]
10. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase.
Choi HJ; Smithgall TE
J Mol Biol; 2004 Nov; 343(5):1255-68. PubMed ID: 15491611
[TBL] [Abstract][Full Text] [Related]
11. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
Briggs SD; Lerner EC; Smithgall TE
Biochemistry; 2000 Jan; 39(3):489-95. PubMed ID: 10642173
[TBL] [Abstract][Full Text] [Related]
12. Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor.
Trible RP; Emert-Sedlak L; Wales TE; Ayyavoo V; Engen JR; Smithgall TE
J Mol Biol; 2007 Nov; 374(1):121-9. PubMed ID: 17920628
[TBL] [Abstract][Full Text] [Related]
13. Synergy and allostery in ligand binding by HIV-1 Nef.
Aldehaiman A; Momin AA; Restouin A; Wang L; Shi X; Aljedani S; Opi S; Lugari A; Shahul Hameed UF; Ponchon L; Morelli X; Huang M; Dumas C; Collette Y; Arold ST
Biochem J; 2021 Apr; 478(8):1525-1545. PubMed ID: 33787846
[TBL] [Abstract][Full Text] [Related]
14. HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.
Trible RP; Emert-Sedlak L; Smithgall TE
J Biol Chem; 2006 Sep; 281(37):27029-38. PubMed ID: 16849330
[TBL] [Abstract][Full Text] [Related]
15. The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.
Chutiwitoonchai N; Hiyoshi M; Mwimanzi P; Ueno T; Adachi A; Ode H; Sato H; Fackler OT; Okada S; Suzu S
PLoS One; 2011; 6(11):e27696. PubMed ID: 22110726
[TBL] [Abstract][Full Text] [Related]
16. SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.
Lerner EC; Smithgall TE
Nat Struct Biol; 2002 May; 9(5):365-9. PubMed ID: 11976726
[TBL] [Abstract][Full Text] [Related]
17. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.
Lee CH; Leung B; Lemmon MA; Zheng J; Cowburn D; Kuriyan J; Saksela K
EMBO J; 1995 Oct; 14(20):5006-15. PubMed ID: 7588629
[TBL] [Abstract][Full Text] [Related]
18. The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Arold S; Franken P; Strub MP; Hoh F; Benichou S; Benarous R; Dumas C
Structure; 1997 Oct; 5(10):1361-72. PubMed ID: 9351809
[TBL] [Abstract][Full Text] [Related]
19. HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon.
Cornall A; Mak J; Greenway A; Tachedjian G
Viruses; 2013 Sep; 5(9):2235-52. PubMed ID: 24051604
[TBL] [Abstract][Full Text] [Related]
20. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
Greenway AL; Dutartre H; Allen K; McPhee DA; Olive D; Collette Y
J Virol; 1999 Jul; 73(7):6152-8. PubMed ID: 10364375
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
