BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 25125662)

  • 1. Translesion polymerase η is upregulated by cancer therapeutics and confers anticancer drug resistance.
    Tomicic MT; Aasland D; Naumann SC; Meise R; Barckhausen C; Kaina B; Christmann M
    Cancer Res; 2014 Oct; 74(19):5585-96. PubMed ID: 25125662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair.
    Barckhausen C; Roos WP; Naumann SC; Kaina B
    Oncogene; 2014 Apr; 33(15):1964-74. PubMed ID: 23604128
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis.
    Jung YS; Hakem A; Hakem R; Chen X
    Mol Cell Biol; 2011 Oct; 31(19):3997-4006. PubMed ID: 21791603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A PolH Transcript with a Short 3'UTR Enhances PolH Expression and Mediates Cisplatin Resistance.
    Zhang J; Sun W; Ren C; Kong X; Yan W; Chen X
    Cancer Res; 2019 Jul; 79(14):3714-3724. PubMed ID: 31064846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs.
    Tomicic MT; Aasland D; Nikolova T; Kaina B; Christmann M
    Biochim Biophys Acta; 2013 Aug; 1833(8):1832-43. PubMed ID: 23578789
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts.
    King NM; Nikolaishvili-Feinberg N; Bryant MF; Luche DD; Heffernan TP; Simpson DA; Hanaoka F; Kaufmann WK; Cordeiro-Stone M
    DNA Repair (Amst); 2005 Jun; 4(6):714-24. PubMed ID: 15886068
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of translesion synthesis DNA polymerases in DNA interstrand crosslink repair.
    Roy U; Schärer OD
    DNA Repair (Amst); 2016 Aug; 44():33-41. PubMed ID: 27311543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2.
    Anderson HJ; Vonarx EJ; Pastushok L; Nakagawa M; Katafuchi A; Gruz P; Di Rubbo A; Grice DM; Osmond MJ; Sakamoto AN; Nohmi T; Xiao W; Kunz BA
    Plant J; 2008 Sep; 55(6):895-908. PubMed ID: 18494853
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy.
    Clingen PH; Wu JY; Miller J; Mistry N; Chin F; Wynne P; Prise KM; Hartley JA
    Biochem Pharmacol; 2008 Jul; 76(1):19-27. PubMed ID: 18508035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability.
    Ren C; Cho SJ; Jung YS; Chen X
    Biochem J; 2014 Dec; 464(3):377-86. PubMed ID: 25268038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA polymerase eta, a key protein in translesion synthesis in human cells.
    Cruet-Hennequart S; Gallagher K; Sokòl AM; Villalan S; Prendergast AM; Carty MP
    Subcell Biochem; 2010; 50():189-209. PubMed ID: 20012583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.
    Jung YS; Liu G; Chen X
    Mol Cell Biol; 2010 Feb; 30(4):1041-8. PubMed ID: 20008555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells.
    Shen YH; Chen BR; Cherng SH; Chueh PJ; Tan X; Lin YW; Lin JC; Chuang SM
    Toxicol Lett; 2011 Sep; 205(3):341-50. PubMed ID: 21742020
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts.
    Bassett E; King NM; Bryant MF; Hector S; Pendyala L; Chaney SG; Cordeiro-Stone M
    Cancer Res; 2004 Sep; 64(18):6469-75. PubMed ID: 15374956
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of p53 protein in normal and in tumor cells by a novel anticancer agent CHS 828.
    Wojciechowski J; Lövborg H; Wesierska-Gadek J
    Drugs Exp Clin Res; 2003; 29(2):53-67. PubMed ID: 12951835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenovirus mediated transduction of the human DNA polymerase eta cDNA.
    Lima-Bessa KM; Chiganças V; Stary A; Kannouche P; Sarasin A; Armelini MG; de Fátima Jacysyn J; Amarante-Mendes GP; Cordeiro-Stone M; Cleaver JE; Menck CF
    DNA Repair (Amst); 2006 Aug; 5(8):925-34. PubMed ID: 16798111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.
    Flanagan AM; Rafferty G; O'Neill A; Rynne L; Kelly J; McCann J; Carty MP
    Int J Mol Med; 2007 Apr; 19(4):589-96. PubMed ID: 17334634
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH).
    Wilson DM; Duncton MAJ; Chang C; Lee Luo C; Georgiadis TM; Pellicena P; Deacon AM; Gao Y; Das D
    Front Oncol; 2021; 11():778925. PubMed ID: 34900730
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
    Li S; Zhao Y; Wang JY
    Mol Immunol; 2013 Mar; 53(3):214-7. PubMed ID: 22960197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation.
    Masuda K; Ouchida R; Yokoi M; Hanaoka F; Azuma T; Wang JY
    Eur J Immunol; 2008 Oct; 38(10):2796-805. PubMed ID: 18825746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.